GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas

Epilepsia

Volumn 49, Issue 5, 2008, Pages 861-871

  Kim, Do Young ^a   Fenoglio, Kristina A ^a   Simeone, Timothy A ^a   Coons, Stephen W ^a   Wu, Jie ^a   Chang, Yongchang ^a   Kerrigan, John F ^a   Rho, Jong M ^a  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Cation chloride cotransporters; Depolarization; GABAA receptor; Hypothalamic hamartoma; L type calcium channel

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE METHIODIDE; BUMETANIDE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CHLORIDE; CHLORIDE TRANSPORT PROTEIN; CHLORIDE TRANSPORT PROTEIN KCC2; CHLORIDE TRANSPORT PROTEIN NKCC1; MUSCIMOL; NIFEDIPINE; CHLORIDE CHANNEL; COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM-CHLORIDE SYMPORTERS; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1 PROTEIN; SODIUM-POTASSIUM-CHLORIDE COTRANSPORTER 1 PROTEIN;

ADOLESCENT; ADULT; ARTICLE; CALCIUM TRANSPORT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EPILEPTOGENESIS; FEMALE; GABAERGIC SYSTEM; GELASTIC SEIZURE; HAMARTOMA; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; INFANT; MALE; NERVE CELL EXCITABILITY; PRIORITY JOURNAL; ACTION POTENTIAL; BIOLOGICAL MODEL; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; DRUG EFFECT; FOCAL EPILEPSY; HYPOTHALAMUS DISEASE; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVE CELL; PATCH CLAMP; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD;

ACTION POTENTIALS; ADOLESCENT; ADULT; CALCIUM CHANNELS, L-TYPE; CHILD, PRESCHOOL; CHLORIDE CHANNELS; EPILEPSIES, PARTIAL; FEMALE; HAMARTOMA; HUMANS; HYPOTHALAMIC DISEASES; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; MUSCIMOL; NEURONS; NIFEDIPINE; PATCH-CLAMP TECHNIQUES; RECEPTORS, GABA-A; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; SYMPORTERS;

EID: 43249120804     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.01455.x     Document Type: Article

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