Synthesis, anti-bacterial, anti-asthmatic and anti-diabetic activities of novel N-substituted-2-(4-phenylethynyl-phenyl)-1H-benzimidazoles and N-substituted 2[4-(4,4-dimethyl-thiochroman-6-yl-ethynyl)-phenyl)-1H-benzimidazoles

European Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2008, Pages 986-995

  Vinodkumar, Ramanatham ^a   Vaidya, Sanjay Dashrath ^a,b   Siva Kumar, Bobba Venkata ^a   Bhise, Umesh Nanasaheb ^a   Bhirud, Shekhar Bhaskar ^a   Mashelkar, Uday Chandrakant ^b  

^a Glenmark Pharmaceuticals Limited   (India)

^b Patkar College   (India)

Author keywords

Acylations; Alkylations; Anti asthmatic; Anti bacterial; Anti diabetic; Benzimidazole; Sonogashira coupling

Indexed keywords

ANTIASTHMATIC AGENT; ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT; BENZIMIDAZOLE DERIVATIVE; THIOCHROMAN DERIVATIVE;

ALKYLATION; ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; SONOGASHIRA REACTION;

ALKYNES; ANTI-ASTHMATIC AGENTS; ANTI-BACTERIAL AGENTS; ANTIGENS, CD26; BENZIMIDAZOLES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; HETEROCYCLIC COMPOUNDS, 2-RING; HUMANS; HYPOGLYCEMIC AGENTS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 43249115967     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.06.013     Document Type: Article

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