Blockade of group II, but not group I, mGluRs in the rat nucleus accumbens inhibits the expression of conditioned hyperactivity in an amphetamine-associated environment

Behavioural Brain Research

Volumn 191, Issue 1, 2008, Pages 62-66

  Kim, Wha Young ^a   Vezina, Paul ^b   Kim, Jeong Hoon ^a  

^a Brain Research Institute   (South Korea)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Amphetamine; Conditioned locomotion; mGluR; Nucleus accumbens

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; ALPHA ETHYLGLUTAMIC ACID; AMPHETAMINE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; METABOTROPIC GLUTAMATE RECEPTOR 1 ANTAGONIST; METABOTROPIC GLUTAMATE RECEPTOR 2 ANTAGONIST; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERACTIVITY; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

AMPHETAMINE; ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMATES; HYPERKINESIS; INDANS; MALE; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 43249099978     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.03.010     Document Type: Article

References (48)

1. Anagnostaras S.G., Schallert T., and Robinson T.E. Memory processes governing amphetamine-induced psychomotor sensitization. Neuropsychopharmacology 26 (2002) 703-715
2. Attarian S., and Amalric M. Microinfusion of the metabotropic glutamate receptor agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid into the nucleus accumbens induces dopamine-dependent locomotor activation in the rat. Eur J Neurosci 9 (1997) 809-816
3. Baptista M.A., Martin-Fardon R., and Weiss F. Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer. J Neurosci 24 (2004) 4723-4727
4. Bell K., Duffy P., and Kalivas P.W. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology 23 (2000) 335-344
5. 2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking. NeuroReport 16 (2005) 1013-1016
6. Bossert J.M., Gray S.M., Lu L., and Shaham Y. Activation of group II mGluRs in the nucleus accumbens shell attenuates context-induced relapse of heroin seeking. Neuropsychopharmacology 31 (2006) 2197-2209
7. Childress A.R., McLellan A.T., and O'Brien C.P. Abstinent opiate abusers exhibit conditioned craving, conditioned withdrawal and reductions in both through extinction. Br J Addict 81 (1986) 655-660
8. DiChiara G., and Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85 (1988) 274-5278
9. DiCiano P., Blaha C.D., and Phillips A.G. The relation between dopamine oxidation currents in the nucleus accumbens and conditioned increases in motor activity in rats following repeated administration of d-amphetamine or cocaine. Eur J Neurosci 10 (1988) 1113-1120
10. Domjan M. Pavlovian conditioning: a functional perspective. Ann Rev Psychol 56 (2005) 179-206
11. Fontana D.J., Post R.M., and Pert A. Conditioned increases in mesolimbic dopamine overflow by stimuli associated with cocaine. Brain Res 629 (1993) 31-39
12. Franklin T.R., and Druhan J.P. Involvement of the nucleus accumbens and medial prefrontal cortex in the expression of conditioned hyperactivity to a cocaine-associated environment in rats. Neuropsychopharmacology 23 (2000) 633-644
13. Franklin T.R., and Druhan J.P. Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment. Eur J Neurosci 12 (2000) 2097-2106
14. Fuchs R.A., Evans K.A., Parker M.C., and See R.E. Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology 176 (2004) 459-465
15. Gerber U., Gee C.E., and Benquet P. Metabotropic glutamate receptors: intracellular signaling pathways. Curr Opin Pharmacol 7 (2007) 56-61
16. Gerdjikov T.V., and Beninger R.J. Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of group II mGluRs in rats. BMC Neurosci 7 (2006) 43
17. Gold L.H., Swerdlow N.R., and Koob G.F. The role of mesolimbic dopamine in conditioned locomotion produced by amphetamine. Behav Neurosci 102 (1988) 544-552
18. Hall J., Parkinson J.A., Connor T.M., Dickinson A., and Everitt B.J. Involvement of the central nucleus of the amygdala and nucleus accumbens core in mediating Pavlovian influences on instrumental behaviour. Eur J Neurosci 13 (2001) 1984-1992
19. Hotsenpiller G., Giorgetti M., and Wolf M.E. Alterations in behavior and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. Eur J Neurosci 14 (2001) 1843-1855
20. Ito R., Dalley J.W., Howes S.R., Robbins T.W., and Everitt B.J. Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats. J Neurosci 20 (2000) 7480-7495
21. Jongen-Relo A.L., Groenewegen H.J., and Voorn P. Evidence for a multicompartmental histochemical organization of the nucleus accumbens in the rat. J Comp Neurol 337 (1993) 267-276
22. Kim J.-H., and Vezina P. Activation of metabotropic glutamate receptors in the rat nucleus accumbens increases locomotor activity in a dopamine-dependent manner. J Pharmacol Exp Ther 283 (1997) 962-968
23. Kim J.-H., and Vezina P. Metabotropic glutamate receptors in the rat nucleus accumbens contribute to amphetamine-induced locomotion. J Pharmacol Exp Ther 284 (1998) 317-322
24. Kim J.-H., and Vezina P. Metabotropic glutamate receptors are necessary for sensitization by amphetamine. NeuroReport 9 (1998) 403-406
25. Kim J.-H., Beeler J.A., and Vezina P. Group II, but not group I, mGluRs in rat nucleus accumbens contribute to amphetamine-induced locomotion. Neuropharmacology 39 (2000) 1692-1699
26. Kim J.-H., Austin J.D., Tanabe L., Creekmore E., and Vezina P. Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine. Eur J Neurosci 21 (2005) 295-300
27. Neisewander J.L., Baker D.A., Fuchs R.A., Tran-Nguyen L.T.L., Palmer A., and Marshall J.F. Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. J Neurosci 20 (2000) 798-805
28. Nicola S.M., Taha S.A., Kim S.W., and Fields H.L. Nucleus accumbens dopamine release is necessary and sufficient to promote the behavioral response to reward-predictive cues. Neuroscience 135 (2005) 1025-1033
29. O'Brien C.P., Childress A.R., McLellan A.T., and Ehrman R. Classical conditioning in drug-dependent humans. Ann N Y Acad Sci 654 (1992) 400-415
30. Parkinson J.A., Olmstead M.C., Burns L.H., Robbins T.W., and Everitt B.J. Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive Pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by d-amphetamine. J Neurosci 19 (1999) 2401-2411
31. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. third ed. (1997), Academic Press, New York
32. Pellegrino L.J., Pellegrino A.S., and Cushman A.J. A stereotaxic atlas of the rat brain. second ed. (1979), Plenum, New York
33. Pin J.-P., and Duvoisin R. The metabotropic glutamate receptors: structures and functions. Neuropharmacology 34 (1995) 1-26
34. Riedel G., Harrington N.R., Kozikowski A.P., Sandager-Nielsen K., and Macphail E.M. Variation of CS salience reveals group II mGluR-dependent and -independent forms of conditioning in the rat. Neuropharmacology 43 (2002) 205-214
35. Robledo P., Maldonado-Lopez R., and Koob G.F. Role of dopamine receptors in the nucleus accumbens in the rewarding properties of cocaine. Ann N Y Acad Sci 654 (1992) 509-512
36. Schachtman T.R., Bills C., Ghinescu R., Murch K., Serfozo P., and Simonyi A. MPEP, a selective mGluR 5 antagonist, attenuates conditioned taste aversion in rats. Behav Brain Res 141 (2003) 177-182
37. Schoepp D.D., and Conn P.J. Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol Sci 14 (1993) 13-20
38. Schroeder B.E., Holahan M.R., Landry C.F., and Kelley A.E. Morphine-associated environmental cues elicit conditioned gene expression. Synapse 37 (2000) 146-158
39. Sellings L.H.L., and Clarke P.B.S. 6-Hydroxydopamine lesions of nucleus accumbens core abolish amphetamine-induced conditioned activity. Synapse 59 (2006) 374-377
40. Sesack S.R., and Pickel V.M. In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spiny neurons and are in apposition to each other. Brain Res 527 (1990) 266-279
41. Sesack S.R., and Pickel V.M. Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J Comp Neurol 320 (1992) 145-160
42. Stewart J., de Wit H., and Eikelboom R. Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants. Psychol Rev 91 (1984) 251-268
43. Stewart J., and Vezina P. Conditioning and behavioral sensitization. In: Kalivas P.W., and Barnes C.D. (Eds). Sensitization in the nervous system (1988), Telford Press, Caldwell, NJ 207-224
44. Sutton M.A., McGibney K., and Beninger R.J. Conditioned locomotion in rats following amphetamine infusion into the nucleus accumbens: blockade by coincident inhibition of protein kinase A. Behav Pharmacol 11 (2000) 365-376
45. Swanson C.J., and Kalivas P.W. Regulation of locomotor activity by metabotropic glutamate receptors in the nucleus accumbens and ventral tegmental area. J Pharmacol Exp Ther 292 (2000) 406-414
46. Testa C.M., Standaert D.G., Young A.B., and Penney Jr. J.B. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J Neurosci 14 (1994) 3005-3018
47. Vezina P., and Kim J.-H. Metabotropic glutamate receptors and the generation of locomotor activity: interactions with midbrain dopamine. Neurosci Biobehav Rev 23 (1999) 577-589
48. Zahm D. An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbens. Neurosci Biobehav Rev 24 (2000) 85-105