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1
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34147142378
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Kindling epileptogenesis in immature rats leads to persistent depressive behavior
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This is one of the few experimental research studies published in the literature that investigates the relation between depressive symptoms and epilepsy using animal models of epilepsy and of mood disorders
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Mazarati A, Shin D, Auvin S, et al. Kindling epileptogenesis in immature rats leads to persistent depressive behavior. Epilepsy Behav 2007; 10:377-383. This is one of the few experimental research studies published in the literature that investigates the relation between depressive symptoms and epilepsy using animal models of epilepsy and of mood disorders.
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(2007)
Epilepsy Behav
, vol.10
, pp. 377-383
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Mazarati, A.1
Shin, D.2
Auvin, S.3
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2
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36349023589
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Psychiatric comorbidity in epilepsy: A population-based analysis
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This is an important study as it portrays a representative prevalence of psychiatric comorbidities in the general population
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Tellez-Zenteno JF, Patten SB, Jetté N, et al. Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia 2007; 48:2336-2344. This is an important study as it portrays a representative prevalence of psychiatric comorbidities in the general population.
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(2007)
Epilepsia
, vol.48
, pp. 2336-2344
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Tellez-Zenteno, J.F.1
Patten, S.B.2
Jetté, N.3
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3
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34447307119
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Epilepsy and risk of suicide: A population-based case-control study
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This population-based study alerts clinicians to the higher suicidal risk of patients with epilepsy, and particularly to its occurrence in the early months after the diagnosis is made
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Christensen J, Vestergaard M, Mortensen PB, et al. Epilepsy and risk of suicide: a population-based case-control study. Lancet Neurol 2007; 6:666-667. This population-based study alerts clinicians to the higher suicidal risk of patients with epilepsy, and particularly to its occurrence in the early months after the diagnosis is made.
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(2007)
Lancet Neurol
, vol.6
, pp. 666-667
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Christensen, J.1
Vestergaard, M.2
Mortensen, P.B.3
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4
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0025311673
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An incident case referent study of epileptic seizures in adults
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Forsgren L, Nystrom L. An incident case referent study of epileptic seizures in adults. Epilepsy Res 1999; 6:66-81.
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(1999)
Epilepsy Res
, vol.6
, pp. 66-81
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Forsgren, L.1
Nystrom, L.2
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5
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0033950568
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Major depression is a risk factor for seizures in older adults
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Hesdorffer DC, Hauser WA, Annegers JF, et al. Major depression is a risk factor for seizures in older adults. Ann Neurol 2000; 47:246-249.
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(2000)
Ann Neurol
, vol.47
, pp. 246-249
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Hesdorffer, D.C.1
Hauser, W.A.2
Annegers, J.F.3
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6
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29944444922
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Depression and suicidal attempt as risk factor for incidental unprovoked seizures
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This important population-based study illustrates the bidirectional relation between mood disorder and epilepsy
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Hesdorffer DC, Hauser WA, Olafsson E, et al. Depression and suicidal attempt as risk factor for incidental unprovoked seizures. Ann Neurol 2006; 59:35-41. This important population-based study illustrates the bidirectional relation between mood disorder and epilepsy.
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(2006)
Ann Neurol
, vol.59
, pp. 35-41
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Hesdorffer, D.C.1
Hauser, W.A.2
Olafsson, E.3
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7
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34347378673
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Behavior and social competency in idiopathic and cryptogenic childhood epilepsy
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Berg AT, Vickrey BG, Testa FM, et al. Behavior and social competency in idiopathic and cryptogenic childhood epilepsy. Dev Med Child Neurol 2007; 49:487-492.
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(2007)
Dev Med Child Neurol
, vol.49
, pp. 487-492
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Berg, A.T.1
Vickrey, B.G.2
Testa, F.M.3
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8
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34347380557
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Psychiatric comorbidity in children with new onset epilepsy
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This study illustrates the relatively frequent existence of psychiatric pathology before the onset of any seizure in children with idiopathic or cryptogenic epilepsy
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Jones JE, Watson R, Sheth R, et al. Psychiatric comorbidity in children with new onset epilepsy. Dev Med Child Neurol 2007; 49:493-497. This study illustrates the relatively frequent existence of psychiatric pathology before the onset of any seizure in children with idiopathic or cryptogenic epilepsy.
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(2007)
Dev Med Child Neurol
, vol.49
, pp. 493-497
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Jones, J.E.1
Watson, R.2
Sheth, R.3
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9
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34249777255
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The incidence of first unprovoked seizure in pediatric patients with and without psychiatric diagnoses
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McAfee AT, Chilcott KE, Johannes CB, et al. The incidence of first unprovoked seizure in pediatric patients with and without psychiatric diagnoses. Epilepsia 2007; 48:1075-1082.
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(2007)
Epilepsia
, vol.48
, pp. 1075-1082
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McAfee, A.T.1
Chilcott, K.E.2
Johannes, C.B.3
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10
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34447268949
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Predictors of pharmacoresistant epilepsy
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This study demonstrates that a history of depression preceding or present at the onset of epilepsy is predictive of a pharmacoresistant seizure disorder
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Hitiris N, Mohanraj R, Norrie J, et al. Predictors of pharmacoresistant epilepsy. Epilepsy Res 2007; 75:192-196. This study demonstrates that a history of depression preceding or present at the onset of epilepsy is predictive of a pharmacoresistant seizure disorder.
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(2007)
Epilepsy Res
, vol.75
, pp. 192-196
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Hitiris, N.1
Mohanraj, R.2
Norrie, J.3
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12
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34447250921
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Does a lifetime history of depression predict a worse postsurgical seizure outcome following a temporal lobectomy? [abstract]
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Kanner AM, Byrne R, Smith MC, et al. Does a lifetime history of depression predict a worse postsurgical seizure outcome following a temporal lobectomy? [abstract]. Ann Neurol 2006; 60 (Suppl 10):19.
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(2006)
Ann Neurol
, vol.60
, Issue.SUPPL. 10
, pp. 19
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Kanner, A.M.1
Byrne, R.2
Smith, M.C.3
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13
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33646674597
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Current review in clinical science: Depression in epilepsy: a neurobiologic perspective
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Kanner AM. Current review in clinical science: depression in epilepsy: a neurobiologic perspective. Epilepsy Curr 2005; 5:21-27.
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(2005)
Epilepsy Curr
, vol.5
, pp. 21-27
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Kanner, A.M.1
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14
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35848942392
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5-HT(1A) receptor binding in temporal lobe epilepsy patients with and without major depression
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This study illustrates one of the common pathogenic mechanisms operant in primary depressive disorders and epilepsy
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Hasler G, Bonwetsch R, Giovacchini G, et al. 5-HT(1A) receptor binding in temporal lobe epilepsy patients with and without major depression. Biol Psychiatry 2007; 62:1258-1264. This study illustrates one of the common pathogenic mechanisms operant in primary depressive disorders and epilepsy.
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(2007)
Biol Psychiatry
, vol.62
, pp. 1258-1264
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Hasler, G.1
Bonwetsch, R.2
Giovacchini, G.3
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15
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33644809269
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The effect of antiepileptic drugs on 5-HT-receptor binding measured by positron emission tomography
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This study illustrates one of the common pathogenic mechanisms operant in primary depressive disorders and epilepsy
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Theodore WH, Giovacchini G, Bonwetsch R, et al. The effect of antiepileptic drugs on 5-HT-receptor binding measured by positron emission tomography. Epilepsia 2006; 47:499-503. This study illustrates one of the common pathogenic mechanisms operant in primary depressive disorders and epilepsy.
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(2006)
Epilepsia
, vol.47
, pp. 499-503
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Theodore, W.H.1
Giovacchini, G.2
Bonwetsch, R.3
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16
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0032731312
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PET imaging of serotonin 1A receptor binding in depression
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Drevets WC, Frank E, Price JC, et al. PET imaging of serotonin 1A receptor binding in depression. Biol Psychiatry 1999; 46:1375-1387.
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(1999)
Biol Psychiatry
, vol.46
, pp. 1375-1387
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Drevets, W.C.1
Frank, E.2
Price, J.C.3
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17
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33846601405
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1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy
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1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy. Neurology 2007; 68:364-368.
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(2007)
Neurology
, vol.68
, pp. 364-368
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Gilliam, F.G.1
Maton, B.M.2
Martin, R.C.3
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18
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0033303233
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A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders
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Jobe PC, Dailey JW, Wernicke JF. A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders. Crit Rev Neurobiol 1999; 13:317-356.
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(1999)
Crit Rev Neurobiol
, vol.13
, pp. 317-356
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Jobe, P.C.1
Dailey, J.W.2
Wernicke, J.F.3
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19
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34548846929
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Seizure incidence in psychopharmacological clinical trials: An analysis of Food and Drug Administration (FDA) summary basis of approval reports
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This is a pivotal study that demonstrates the safety of using antidepressant drugs of the families of SSRIs and serotonin-norepinephrine reuptake inhibitors with respect to the risk of seizure occurrence
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Alper K, Schwartz KA, Kolts RL, Khan A. Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports. Biol Psychiatry 2007; 62:345-354. This is a pivotal study that demonstrates the safety of using antidepressant drugs of the families of SSRIs and serotonin-norepinephrine reuptake inhibitors with respect to the risk of seizure occurrence.
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(2007)
Biol Psychiatry
, vol.62
, pp. 345-354
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Alper, K.1
Schwartz, K.A.2
Kolts, R.L.3
Khan, A.4
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20
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33646067133
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Rapid detection of major depression in epilepsy: A multicenter study
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This study provides a very practical and user-friendly screening instrument to identify major depressive episodes in epilepsy patients
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Gilliam FG, Barry JJ, Meador KJ, et al. Rapid detection of major depression in epilepsy: a multicenter study. Lancet Neurol 2006; 5:399-405. This study provides a very practical and user-friendly screening instrument to identify major depressive episodes in epilepsy patients.
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(2006)
Lancet Neurol
, vol.5
, pp. 399-405
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Gilliam, F.G.1
Barry, J.J.2
Meador, K.J.3
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