Diversifying and purifying selection in the peptide binding region of DRB in mammals

Journal of Molecular Evolution

Volumn 66, Issue 4, 2008, Pages 384-394

  Furlong, Rebecca F ^a,b   Yang, Ziheng ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Darwinian selection; DRB; Major histocompatibility complex; Positive selection; Purifying selection

Indexed keywords

AMINO ACID; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLELE; ANTHROPOIDEA; ANTIGEN PRESENTATION; ARTICLE; BINDING SITE; CHIMPANZEE; CODON; COW; DIMERIZATION; DOG; DRB GENE; EVOLUTION; GENE; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; HABITAT; HUMAN; MACACA; MAJOR HISTOCOMPATIBILITY COMPLEX; MAMMAL; MAXIMUM LIKELIHOOD METHOD; NATURAL SELECTION; NONHUMAN; T LYMPHOCYTE;

ALLELES; AMINO ACIDS; ANIMALS; BINDING SITES; CATTLE; DOGS; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MAMMALS; MODELS, MOLECULAR; PEPTIDES; RECOMBINATION, GENETIC; SELECTION (GENETICS);

CANIS FAMILIARIS; MAMMALIA; PAN; SAGUINUS IMPERATOR;

EID: 43149093122     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-008-9092-6     Document Type: Article

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