Controlled delivery of aspirin: Effect of aspirin on polymer degradation and in vitro release from PLGA based phase sensitive systems

International Journal of Pharmaceutics

Volumn 357, Issue 1-2, 2008, Pages 119-125

  Tang, Yu ^a   Singh, Jagdish ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Aspirin; Controlled delivery; Phase sensitive in situ gel forming drug delivery system; PLGA; Polymer degradation

Indexed keywords

1 METHYL 2 PYRROLIDINONE; ACETYLSALICYLIC ACID; MACROGOL 400; POLYGLACTIN;

ARTICLE; CONTROLLED RELEASE FORMULATION; DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG FORMULATION; DRUG RELEASE; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, GEL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; POLYGLYCOLIC ACID;

EID: 43049180016     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.01.053     Document Type: Article

References (26)

1. Bakar S.K., and Niazi S. Stability of aspirin in different media. J. Pharm. Sci. 72 (1983) 1024-1026
2. Cortizo M.S., Alessandrini J.L., Etcheverry S.B., and Cortizo A.M. A vanadium/aspirin complex controlled release using a poly(β-propiolactone) film. Effects on osteosarcoma cells. J. Biomater. Sci. Polym. Ed. 12 (2001) 945-959
3. Dong W.Y., KÖrber M., Esguerra V.L., and Bodmeier R. Stability of poly(d,l-lactide-co-glycolide) and leuprolide acetate in in-situ forming drug delivery systems. J. Controlled Release 115 (2006) 158-167
4. Dunn, R.L., English, J.P., Cowsar, D.R., Vanderbelt, D.P., 1990. Biodegradable in-situ forming implants and methods of producing the same. US Patent 4 938 763, 3 July.
5. Graham P.D., Brodbeck K.J., and McHugh A.J. Phase inversion dynamics of PLGA solutions related to drug delivery. J. Controlled Release 58 (1999) 233-245
6. Guslandi M. Gastric toxicity of antiplatelet therapy with low-dose aspirin. Drugs 53 (1997) 1-5
7. Hall J.D., Rittgers S.E., and Schemidt S.P. Effect of controlled local acetylsalicylic aid release on in vitro platelet adhesion to vascular grafts. J. Biomater. Appl. 8 (1994) 361-384
8. Hasirci V., Lewandrowski K., Gresser J.D., Wise D.L., and Trantolo D.J. Versatility of biodegradable biopolymers: degradability and in vivo application. J. Biotechnol. 86 (2001) 135-150
9. Huh K.M., Cho Y.W., and Park K. PLGA-PEG block copolymers for drug formulations. Drug Deliv. Technol. 3 (2003). http://www.drugdeliverytech.com/cgi-bin/articles.cgi%3FidArticle=152 http://www.drugdeliverytech.com/cgi-bin/articles.cgi?idArticle=152 (accessed 04/08/07)
10. Ikada Y., and Tsuji H. Biodegradable polyesters for medical and ecological applications. Macromol. Rapid Commun. 21 (2000) 117-132
11. Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide)) (PLGA) devices. Biomaterials 21 (2000) 2475-2490
12. Kiortosis S., Kachrimanis K., Broussali Th., and Malamataris S. Drug release from tableted wet granulations comprising cellulosic (HPMC or HPC) and hydrophobic component. Eur. J. Pharm. Biopharm. 59 (2005) 73-83
13. Lambert W.J., and Peck K.D. Development of an in situ forming biodegradable poly-lactide-co-glycolide system for the controlled release of proteins. J. Controlled Release 33 (1995) 189-195
14. Lee M., Cryer B., and Feldman M. Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury. Ann. Intern. Med. 130 (1994) 184-189
15. Leton J.C., and Tipton A.J. Synthetic biodegradable polymers as medical devices. Med. Plastics Biomater. 5 (1998) 30-39
16. Li S., Garreau H., and Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly-(α-hydroxy acids) in aqueous media. Part 1: Poly (dl-lactic acid). J. Mater. Sci.: Mater. Med. 1 (1990) 123-130
17. Li S., Garreau H., and Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly-(α-hydroxy acids) in aqueous media. Part 2. Degradation of lactide-glycolide copolymers: PLA 37.5 GA25 and PLA 75 GA 25. J. Mater. Sci.: Mater. Med. 1 (1990) 131-139
18. Pedersen A.K., and FitzGeral G.A. Dose-related kinetics of aspirin. N. Engl. J. Med. 311 (1984) 1206-1211
19. Ramchandani M., Pankaskie M., and Robinson D. The influence of manufacturing procedure on the degradation of poly(lactide-co-glycolide) 85:15 and 50:50 implants. J. Controlled Release 43 (1997) 161-173
20. Roberts M.S., Mcleod L.J., Cossum P.A., and Vial J.H. Inhibition of platelet function by a controlled release acetylsalicylic acid formulation-single and chronic dosing studies. Eur. J. Clin. Pharmacol. 27 (1984) 67-74
21. Siegel S.J., Kahn J.B., Metzger K., Winey K.I., Werner K., and Dan N. Effect of drug type on the degradation rate of PLGA matrices. Eur. J. Pharm. Biopharm. 64 (2006) 287-293
22. Sztriha L.K., Sas K., and Vecsei L. Aspirin resistance in stroke: 2004. J. Neurol. Sci. 229 (2005) 163-169
23. Tan L.P., Venkatraman S.S., Sung P.F., and Wang X.T. Effect of plasticization on heparin release from biodegradable matrices. Int. J. Pharm. 283 (2004) 89-96
24. Tsukagoshi T., Kondo Y., and Yoshino N. Preparation of thin polymer films with drug release and protein adsorption resistance. Colloids Surf. B Biointerfaces 55 (2007) 19-25
25. Vasudev S.V., Chandy T., and Sharma C.P. Development of chitosan/polyethylene vinyl acetate co-matrix: controlled release of aspirin-heparin for preventing cardiovascular thrombosis. Biomaterials 18 (1997) 375-381
26. Wang L.W., Venkatraman S., and Kleiner L. Drug release from injectable depots: two different in vitro mechanisms. J. Controlled Release 99 (2004) 207-216