메뉴 건너뛰기




Volumn 9, Issue 7, 2008, Pages 1197-1209

Experience with tenofovir disoproxil fumarate for antiretroviral therapy

Author keywords

Efficacy; Hepatitis B; Renal safety; Safety; Switch studies; Tenofovir; Viread

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE; ADEFOVIR; ADEFOVIR DIPIVOXIL; ALANINE AMINOTRANSFERASE; ANTIVIRUS AGENT; ASPARTATE AMINOTRANSFERASE; ATAZANAVIR; CIDOFOVIR; CREATININE; DIDANOSINE; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EFAVIRENZ PLUS LAMIVUDINE PLUS STAVUDINE; EFAVIRENZ PLUS LAMIVUDINE PLUS TENOFOVIR DISOPROXIL; EFAVIRENZ PLUS LAMIVUDINE PLUS ZIDOVUDINE; EMTRICITABINE; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; FORCAVIR; FOSCARNET; GANCICLOVIR; LAMIVUDINE; PLACEBO; RIBAVIRIN; RITONAVIR; STAVUDINE; TENOFOVIR DISOPROXIL; VALGANCICLOVIR; VIDEX EC; ZIDOVUDINE; ADENINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; DRUG DERIVATIVE; PHOSPHONIC ACID DERIVATIVE;

EID: 43049173642     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.9.7.1197     Document Type: Article
Times cited : (8)

References (70)
  • 1
    • 44249085627 scopus 로고    scopus 로고
    • Viread, 5 February 2002. Available from:, Last accessed 14 December 2007
    • European Medicines Evaluation Agency (EMEA). Tenofovir disoproxil (Viread). 5 February 2002. Available from: http://www.emea.europa.eu/ humandocs/PDFs/EPAR/viread/H-419-PI-en.pdf [Last accessed 14 December 2007]
    • Tenofovir disoproxil
  • 5
    • 27944511495 scopus 로고    scopus 로고
    • Dose-dependent influence of didanosine on immune recovery in HIV-inficced patients treated with tenofavir
    • Karrer U, Ledergerber B, Furrer H, et al. Dose-dependent influence of didanosine on immune recovery in HIV-inficced patients treated with tenofavir. AIDS 2005;19:1987-94
    • (2005) AIDS , vol.19 , pp. 1987-1994
    • Karrer, U.1    Ledergerber, B.2    Furrer, H.3
  • 6
    • 0141780963 scopus 로고    scopus 로고
    • Pancreatitis with didanosine and tenofovir disoproxil fumarate [corrected]
    • Blanchard JN, Wohlfeiler M, Canas A, et al. Pancreatitis with didanosine and tenofovir disoproxil fumarate [corrected]. Clin Infect Dis 2003;37:e57-62
    • (2003) Clin Infect Dis , vol.37
    • Blanchard, J.N.1    Wohlfeiler, M.2    Canas, A.3
  • 7
    • 33745792782 scopus 로고    scopus 로고
    • Virological responses to atazanavir-ritonavir-based regimens: Resistance-substitutions score and pharmacokinetic parameters (Reyaphar study)
    • Pellegrin I, Breilh D, Ragnaud JM, et al. Virological responses to atazanavir-ritonavir-based regimens: resistance-substitutions score and pharmacokinetic parameters (Reyaphar study). Antivir Ther 2006;11:421-9
    • (2006) Antivir Ther , vol.11 , pp. 421-429
    • Pellegrin, I.1    Breilh, D.2    Ragnaud, J.M.3
  • 8
    • 25144448034 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir
    • Le Tiec C, Barrail A, Goujard C, Taburet AM. Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir. Clin Pharmacokinet 2005;44:1035-50
    • (2005) Clin Pharmacokinet , vol.44 , pp. 1035-1050
    • Le Tiec, C.1    Barrail, A.2    Goujard, C.3    Taburet, A.M.4
  • 9
    • 17844387166 scopus 로고    scopus 로고
    • Arazanavit plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures
    • Johnson M, Grinsztejn B, Rodriguez C, et al. Arazanavit plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures. AIDS 2005;19:685-94
    • (2005) AIDS , vol.19 , pp. 685-694
    • Johnson, M.1    Grinsztejn, B.2    Rodriguez, C.3
  • 10
    • 2542502584 scopus 로고    scopus 로고
    • Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients
    • Taburet AM, Piketty C, Chazallon C, et al. Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2004;48(6):2091-6
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.6 , pp. 2091-2096
    • Taburet, A.M.1    Piketty, C.2    Chazallon, C.3
  • 11
    • 0344237452 scopus 로고    scopus 로고
    • Pharmacokinetic (PK) evaluation of the combination of atazanavir (ATV), enteric coated didanosine (ddI-EC), and tenofovir disoproxil fumarate (TDF) for a once-daily antiretroviral regimen. [abstrac A-1616]
    • Chicago;
    • Kaul S, Bassi K, Damle B, et al. Pharmacokinetic (PK) evaluation of the combination of atazanavir (ATV), enteric coated didanosine (ddI-EC), and tenofovir disoproxil fumarate (TDF) for a once-daily antiretroviral regimen. [abstrac A-1616]. 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy; Chicago; 2003
    • (2003) 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Kaul, S.1    Bassi, K.2    Damle, B.3
  • 12
    • 27944472569 scopus 로고    scopus 로고
    • ESS30009: Early virologic non-response to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive patients
    • Gallant JE, Rodriguez AE, Weinberg WG, et al. ESS30009: early virologic non-response to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive patients. J Infect Dis 2005;192:1921-30
    • (2005) J Infect Dis , vol.192 , pp. 1921-1930
    • Gallant, J.E.1    Rodriguez, A.E.2    Weinberg, W.G.3
  • 13
    • 23044486337 scopus 로고    scopus 로고
    • Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial
    • Maitland D, Moyle G, Hand J, et al. Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial. AIDS 2005;19:1183-8
    • (2005) AIDS , vol.19 , pp. 1183-1188
    • Maitland, D.1    Moyle, G.2    Hand, J.3
  • 14
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs. stavudine in combination therapy in antiretroviral-naive patents: A randomized trial
    • For the 903 Study Group
    • Gallant JE, Stasziewski S, Pozniak AL, et al. For the 903 Study Group. Efficacy and safety of tenofovir DF vs. stavudine in combination therapy in antiretroviral-naive patents: a randomized trial. JAMA 2004;292:191-201
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, J.E.1    Stasziewski, S.2    Pozniak, A.L.3
  • 15
    • 34547229756 scopus 로고    scopus 로고
    • The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naïve HIV-1-infected patients
    • Cassetti I, Madruga JV, Muhamed AH, et al. The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naïve HIV-1-infected patients. HIV Clin Trials 2007;8:164-72
    • (2007) HIV Clin Trials , vol.8 , pp. 164-172
    • Cassetti, I.1    Madruga, J.V.2    Muhamed, A.H.3
  • 16
    • 39049101609 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis
    • In press
    • Arribas J, Pozniak AI, Gallant JE, et al. Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis. J Acquit Immune Defic Syndr 2008; In press
    • (2008) J Acquit Immune Defic Syndr
    • Arribas, J.1    Pozniak, A.I.2    Gallant, J.E.3
  • 17
    • 1642453729 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate in nucleoside-resistant HIV-1 infection: A randomized trial
    • For the 907 study team
    • Squires K, Pozniak AL, Pierone G Jr, et al. For the 907 study team. Tenofovir disoproxil fumarate in nucleoside-resistant HIV-1 infection: a randomized trial. Ann Intern Med 2003;139:313-20
    • (2003) Ann Intern Med , vol.139 , pp. 313-320
    • Squires, K.1    Pozniak, A.L.2    Pierone Jr, G.3
  • 18
    • 34250854854 scopus 로고    scopus 로고
    • Tenofovir treatment is associated with a decrease in calculated glomendar filtration rates in a large observational cohort
    • abstract 834, Los Angeles;
    • Fux CA, Simcock M, Wolbers M, et al. Tenofovir treatment is associated with a decrease in calculated glomendar filtration rates in a large observational cohort. 14th Conference on Retroviruses and Opportunistic Infections [poster abstract 834]. Los Angeles; 2007
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections [poster
    • Fux, C.A.1    Simcock, M.2    Wolbers, M.3
  • 20
    • 0035822988 scopus 로고    scopus 로고
    • The safety and efficacy of adefovir dipivoxil in patients with advanced HIV disease: A randomized, placebo-controlled trial
    • Fisher EJ, Chaloner K, Cohn DL, et al. The safety and efficacy of adefovir dipivoxil in patients with advanced HIV disease: a randomized, placebo-controlled trial. AIDS 2001;15:1695-700
    • (2001) AIDS , vol.15 , pp. 1695-1700
    • Fisher, E.J.1    Chaloner, K.2    Cohn, D.L.3
  • 21
    • 0033511773 scopus 로고    scopus 로고
    • Cidofovir-induced end-stage renal failure
    • Vandercam B, Moreau M, Goffin E, et al. Cidofovir-induced end-stage renal failure. Clin Infect Dis 1999;29:948-9
    • (1999) Clin Infect Dis , vol.29 , pp. 948-949
    • Vandercam, B.1    Moreau, M.2    Goffin, E.3
  • 22
    • 44249120545 scopus 로고    scopus 로고
    • Ray AS, Vela JE, Robinson KL, et al. Efflux of tenofovir by the multidrug resistance-associated protein 4 (MRP4) is not affected by HIV protease inhibitors [abstract PE4.3/13]. In: Program and abstracts of the 10th European AIDS Conference; Dublin; 2005
    • Ray AS, Vela JE, Robinson KL, et al. Efflux of tenofovir by the multidrug resistance-associated protein 4 (MRP4) is not affected by HIV protease inhibitors [abstract PE4.3/13]. In: Program and abstracts of the 10th European AIDS Conference; Dublin; 2005
  • 23
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 24
    • 0033574249 scopus 로고    scopus 로고
    • A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group
    • Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-70
    • (1999) Ann Intern Med , vol.130 , pp. 461-470
    • Levey, A.S.1    Bosch, J.P.2    Lewis, J.B.3
  • 25
    • 2342639060 scopus 로고    scopus 로고
    • Renal safety of tenofovir in HIV treatment-experienced patients
    • Izzedine H, Isnard-Bagnis C, Hulot J-S, et al. Renal safety of tenofovir in HIV treatment-experienced patients. AIDS 2004;18:1074-6
    • (2004) AIDS , vol.18 , pp. 1074-1076
    • Izzedine, H.1    Isnard-Bagnis, C.2    Hulot, J.-S.3
  • 26
    • 13644255304 scopus 로고    scopus 로고
    • Changes in renal function in patients treated with tenofovir DF (TDF) vs. nucleoside reverse transcriptase inhibitors
    • abstract 751, San Francisco;
    • Parish MA, Gallant JE, Moore R. Changes in renal function in patients treated with tenofovir DF (TDF) vs. nucleoside reverse transcriptase inhibitors [abstract 751]. 11th Conference on Retroviruses and Opportunisitic Infections; San Francisco; 2004
    • (2004) 11th Conference on Retroviruses and Opportunisitic Infections
    • Parish, M.A.1    Gallant, J.E.2    Moore, R.3
  • 27
    • 44249108998 scopus 로고    scopus 로고
    • Renal safety profile of tenofovir DF (TDF)-containing compared to non-TDF-containing regimens through 144 weeks in antiretroviral-naive patients [abstract P9./7/05]
    • October 24-27; Madrid, Spain
    • Gallant JE, Staszewski S, Pozniak AL, et al. Renal safety profile of tenofovir DF (TDF)-containing compared to non-TDF-containing regimens through 144 weeks in antiretroviral-naive patients [abstract P9./7/05]. 11th European AIDS Conference; 2007 October 24-27; Madrid, Spain
    • (2007) 11th European AIDS Conference
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3
  • 28
    • 10044236429 scopus 로고    scopus 로고
    • Renal dysfunction with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy regimens is not observed more frequently: A cohort and case-control study
    • Jones R, Stebbing J, Nelson M, et al. Renal dysfunction with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy regimens is not observed more frequently: a cohort and case-control study. J Acquit Immune Defic Syndr Hum Retrovirol 2004;37:1489-95
    • (2004) J Acquit Immune Defic Syndr Hum Retrovirol , vol.37 , pp. 1489-1495
    • Jones, R.1    Stebbing, J.2    Nelson, M.3
  • 29
    • 16844370820 scopus 로고    scopus 로고
    • Changes in renal function associated with tenofovir disoproxil fumarate treatment compared with nucleoside reverse-transcriptase inhibitor treatment
    • Gallant JE, Parish KA, Keruly JC, Moore RD. Changes in renal function associated with tenofovir disoproxil fumarate treatment compared with nucleoside reverse-transcriptase inhibitor treatment. Clin Infect Dis 2005;40:1194-8
    • (2005) Clin Infect Dis , vol.40 , pp. 1194-1198
    • Gallant, J.E.1    Parish, K.A.2    Keruly, J.C.3    Moore, R.D.4
  • 30
    • 44249102986 scopus 로고    scopus 로고
    • Nelson M, Cooper D, Schooley R, et al. The safety of TDF for the treatment of HIV infection: the first 4 years [poster abstract 781]. 13th Conference on Retroviruses and Opportunistic Infections; Denver, 2006
    • Nelson M, Cooper D, Schooley R, et al. The safety of TDF for the treatment of HIV infection: the first 4 years [poster abstract 781]. 13th Conference on Retroviruses and Opportunistic Infections; Denver, 2006
  • 31
    • 44249104439 scopus 로고    scopus 로고
    • Assessment of drug-induced nephrotoxicity in HIV patients
    • July 19-21; Sydney. Plenary lecture. Available from:, Last accessed 14 December 2007
    • Bagnis C. Assessment of drug-induced nephrotoxicity in HIV patients. Ninth International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV; 2007 July 19-21; Sydney. Plenary lecture. Available from: http://www.intmedpress.com/lipodystrophy/ default.cfm?itemtypeid=15&title=Webcasts#Thursday_19_July_2007 [Last accessed 14 December 2007]
    • (2007) Ninth International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV
    • Bagnis, C.1
  • 32
    • 30944468562 scopus 로고    scopus 로고
    • Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV
    • Available from:, Last accessed 14 December 2007
    • Gallant JE, DeJesus E, Arribas JR, et al. Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. N Engl J Med 2006;354:251-60. Available from: http://content.nejm.org/cgi/ conten/abstract/354/3/251 [Last accessed 14 December 2007]
    • (2006) N Engl J Med , vol.354 , pp. 251-260
    • Gallant, J.E.1    DeJesus, E.2    Arribas, J.R.3
  • 33
    • 21144445218 scopus 로고    scopus 로고
    • Guidelines for the management of chronic kidney disease in HIV-infected patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America
    • Gupta SK, Eustace JA, Winston JA, et al. Guidelines for the management of chronic kidney disease in HIV-infected patients: recommendations of the HIV Medicine Association of the Infectious Diseases Society of America. Clin Infect Dis 2005;40:1559-85
    • (2005) Clin Infect Dis , vol.40 , pp. 1559-1585
    • Gupta, S.K.1    Eustace, J.A.2    Winston, J.A.3
  • 34
    • 33846971989 scopus 로고    scopus 로고
    • Renal safety of tenofovir disoproxil fumarate
    • Sax PE, Gallant JE, Klotman PE. Renal safety of tenofovir disoproxil fumarate. AIDS Reader 2007;17:90-2,99
    • (2007) AIDS Reader , vol.17 , Issue.90-92 , pp. 99
    • Sax, P.E.1    Gallant, J.E.2    Klotman, P.E.3
  • 36
    • 44249120544 scopus 로고    scopus 로고
    • Moyle G, Fisher M; the SWEET DEXA Sub-study Group. Factors associated with low limb fat in a cohort of zidovudine-treated subjects [poster abstract P12]. 9th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV; Sydney; 2007
    • Moyle G, Fisher M; the SWEET DEXA Sub-study Group. Factors associated with low limb fat in a cohort of zidovudine-treated subjects [poster abstract P12]. 9th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV; Sydney; 2007
  • 37
    • 38049173426 scopus 로고    scopus 로고
    • Efficacy and safety of NRTI's switch to tenofovir plus emtricitabine vs. abacavir plus lamivudine in patients with virologic suppression receiving lamivudine containing HAART: The BICOMBO study
    • abstract WESS102, Sydney;
    • Martinez E, Arranz JA, Podzamczer D, et al. Efficacy and safety of NRTI's switch to tenofovir plus emtricitabine vs. abacavir plus lamivudine in patients with virologic suppression receiving lamivudine containing HAART: the BICOMBO study [abstract WESS102]. 4th International AIDS Society Conference on HIV Treatment and Pathogenesis; Sydney; 2007
    • (2007) 4th International AIDS Society Conference on HIV Treatment and Pathogenesis
    • Martinez, E.1    Arranz, J.A.2    Podzamczer, D.3
  • 38
    • 0037006623 scopus 로고    scopus 로고
    • Association between presence of HLA-B 5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
    • Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B 5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002;359:722-3
    • (2002) Lancet , vol.359 , pp. 722-723
    • Mallal, S.1    Nolan, D.2    Witt, C.3
  • 39
    • 2342589533 scopus 로고    scopus 로고
    • Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: The MITOX Extension Study
    • for the Mitochondrial Toxicity (MITOX) Study Group
    • Martin A, Smith D, Carr A, et al. for the Mitochondrial Toxicity (MITOX) Study Group. Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study. AIDS 2004;18:1029-36
    • (2004) AIDS , vol.18 , pp. 1029-1036
    • Martin, A.1    Smith, D.2    Carr, A.3
  • 40
    • 33747646240 scopus 로고    scopus 로고
    • Resistance development over 144 weeks in treatment-naïve patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903
    • Margot NA, Lu B, Cheng A, et al. Resistance development over 144 weeks in treatment-naïve patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903. HIV Med 2006;7:442-50
    • (2006) HIV Med , vol.7 , pp. 442-450
    • Margot, N.A.1    Lu, B.2    Cheng, A.3
  • 41
    • 7244248649 scopus 로고    scopus 로고
    • Patterns of resistance emerging in HIV-1 from antiretroviral-experienced patients undergoing intensification therapy with tenofovir disoproxil fumarate
    • McColl DJ, Margot NA, Wulfsohn M, et al. Patterns of resistance emerging in HIV-1 from antiretroviral-experienced patients undergoing intensification therapy with tenofovir disoproxil fumarate. J Acquit Immune Defic Syndr 2004;37:1340-50
    • (2004) J Acquit Immune Defic Syndr , vol.37 , pp. 1340-1350
    • McColl, D.J.1    Margot, N.A.2    Wulfsohn, M.3
  • 42
    • 0037326980 scopus 로고    scopus 로고
    • The use of tenofovir disoproxil fumarate for the treatment of nucleoside-resistant HIV-1
    • McColl DJ, Miller MD. The use of tenofovir disoproxil fumarate for the treatment of nucleoside-resistant HIV-1. J Antimicrob Chemother 2003;51:219-23
    • (2003) J Antimicrob Chemother , vol.51 , pp. 219-223
    • McColl, D.J.1    Miller, M.D.2
  • 43
    • 33748052358 scopus 로고    scopus 로고
    • Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level
    • Parikh UM, Bamas DC, Faruki H, Mellors JW. Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level. J Infect Dis 2006;194:651-6
    • (2006) J Infect Dis , vol.194 , pp. 651-656
    • Parikh, U.M.1    Bamas, D.C.2    Faruki, H.3    Mellors, J.W.4
  • 44
    • 0038655202 scopus 로고    scopus 로고
    • Multivariate analyses of antiviral response to tenofovir DF therapy in antiretroviral-experienced patients
    • Miller M, Zhong L, Chen S, et al. Multivariate analyses of antiviral response to tenofovir DF therapy in antiretroviral-experienced patients. Antivir Ther 2002;7:16
    • (2002) Antivir Ther , vol.7 , pp. 16
    • Miller, M.1    Zhong, L.2    Chen, S.3
  • 45
    • 33645500469 scopus 로고    scopus 로고
    • The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations
    • White KL, Chen JM, Feng JY, et al. The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations. Antivir Ther 2006;11(2):155-63
    • (2006) Antivir Ther , vol.11 , Issue.2 , pp. 155-163
    • White, K.L.1    Chen, J.M.2    Feng, J.Y.3
  • 46
    • 44149128888 scopus 로고    scopus 로고
    • Staszewski S, Dauer B, Stuermer M, et al. Intensification of a failing regimen with AZT may cause sustained virologic suppression in the presence of the K65R mutation [abstract 89, poster 9.34]. Third European HIV Drug Resistance Workshop; Athens; 2005
    • Staszewski S, Dauer B, Stuermer M, et al. Intensification of a failing regimen with AZT may cause sustained virologic suppression in the presence of the K65R mutation [abstract 89, poster 9.34]. Third European HIV Drug Resistance Workshop; Athens; 2005
  • 47
    • 44249109685 scopus 로고    scopus 로고
    • Long-term safety and efficacy of tenofovir DF versus stavudine in combination with lamivudine and efavirenz in antiretroviral-naïve women: 144 week results
    • abstract MoOrB1083, Bangkok;
    • deRuiter A, Pozniak AL, Staszewski S, et al. Long-term safety and efficacy of tenofovir DF versus stavudine in combination with lamivudine and efavirenz in antiretroviral-naïve women: 144 week results [abstract MoOrB1083]. 15th International AIDS Conference; Bangkok; 2004
    • (2004) 15th International AIDS Conference
    • deRuiter, A.1    Pozniak, A.L.2    Staszewski, S.3
  • 48
    • 2542452668 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adult and Adolescents, Available from:, Last accessed 14 December 2007
    • Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Department of Health and Human Services. 2007:1-143. Available from: http://www.aidsinfo.nih.gov/ContentFiles/ AdultandAdolescentGL.pdf [Last accessed 14 December 2007]
    • (2007) Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents , pp. 1-143
  • 49
    • 44249111194 scopus 로고    scopus 로고
    • Effective MTCT-prophylaxis with AZT, TDF plus FTC or 3TC [poster abstract PE14.2/3]
    • Dublin;
    • Haberl A, Linde R, Faul-Burbes C, et al. Effective MTCT-prophylaxis with AZT, TDF plus FTC or 3TC [poster abstract PE14.2/3]. 10th European AIDS Conference; Dublin; 2005
    • (2005) 10th European AIDS Conference
    • Haberl, A.1    Linde, R.2    Faul-Burbes, C.3
  • 51
    • 44249098737 scopus 로고    scopus 로고
    • and, 25 June 2004. Available from:, Last accessed 14 December 2007
    • US Food and Drug Administration. Viread® US label. 25 June 2004. Available from: http://www.gileadhiv.com/320Viread.aspx [Last accessed 14 December 2007]
    • Viread® US label
    • Food, U.S.1
  • 52
    • 27944509974 scopus 로고    scopus 로고
    • Experience with tenofovir disoproxil fumarate (TDF) in heavily pretreated HIV-infected children
    • abstract TuPeB4465, Bangkok;
    • Ramos JT, Gonzales-Tme MI, Rojo P, et al. Experience with tenofovir disoproxil fumarate (TDF) in heavily pretreated HIV-infected children [abstract TuPeB4465]. 15th International AIDS Conference; Bangkok; 2004
    • (2004) 15th International AIDS Conference
    • Ramos, J.T.1    Gonzales-Tme, M.I.2    Rojo, P.3
  • 53
    • 3142697068 scopus 로고    scopus 로고
    • Efficacy and safety of emtricitabine vs. stavudine in combination therapy in antiretroviral-naïve patients: A randomized trial
    • For the FTC 301 A Study Team
    • Saag M, Cahn P, Raffi F, et al. For the FTC 301 A Study Team. Efficacy and safety of emtricitabine vs. stavudine in combination therapy in antiretroviral-naïve patients: a randomized trial. JAMA 2004;292:180-90
    • (2004) JAMA , vol.292 , pp. 180-190
    • Saag, M.1    Cahn, P.2    Raffi, F.3
  • 54
    • 41549122362 scopus 로고    scopus 로고
    • Available from:, Last accessed 14 December 2007
    • British HIV Association. Treatment of HIV-infected adults with antiretroviral therapy. 2006. Available from: http://www.bhiva.org/ cms1191541.asp [Last accessed 14 December 2007]
    • (2006) Treatment of HIV-infected adults with antiretroviral therapy
  • 55
    • 25844468887 scopus 로고    scopus 로고
    • Summary of positive opinion for Atripla. 18 October, Available from:, Last accessed 14 December 2007
    • European Medicines Evaluation Agency (EMEA). Committee for Medicinal Products for Human Use. Summary of positive opinion for Atripla. 18 October 2007. Available from: http://www.emea.europa.eu/pdfs/human/ opinion/atripla_25587607en.pdf [Last accessed 14 December 2007]
    • (2007) Committee for Medicinal Products for Human Use
  • 56
    • 85019092911 scopus 로고    scopus 로고
    • European Centre for Disease Prevention and Control, published in December, Available from:, last accessed 27 December 2007
    • European Centre for Disease Prevention and Control. Annual epidemiological report on communicable diseases in Europe 2005 (published in December 2007). Available from: http://www.ecdc.europa.eu/ pdf/ECDC_epi_report_2007.pdf [last accessed 27 December 2007]
    • (2005) Annual epidemiological report on communicable diseases in Europe
  • 58
    • 1842607685 scopus 로고    scopus 로고
    • Efficacy of tenofovir disoproxil fumarate in antiretroviral therapy-naive and-experienced patients coinfected with HIV-1 and hepatitis B virus
    • Dore GJ, Cooper DA, Pozniak AL, et al. Efficacy of tenofovir disoproxil fumarate in antiretroviral therapy-naive and-experienced patients coinfected with HIV-1 and hepatitis B virus. J Infect Dis 2004;189:1185-92
    • (2004) J Infect Dis , vol.189 , pp. 1185-1192
    • Dore, G.J.1    Cooper, D.A.2    Pozniak, A.L.3
  • 59
    • 33751002371 scopus 로고    scopus 로고
    • Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and HIV infection: ACTG A5127
    • Peters M, Andersen J, Lynch P, et al. Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and HIV infection: ACTG A5127. Hepatology 2006;44:1110-6
    • (2006) Hepatology , vol.44 , pp. 1110-1116
    • Peters, M.1    Andersen, J.2    Lynch, P.3
  • 60
    • 10644275213 scopus 로고    scopus 로고
    • Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection
    • van Bommel F, Wunsche T, Mauss S, et al. Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection. Hepatology 2004;40:1421-5
    • (2004) Hepatology , vol.40 , pp. 1421-1425
    • van Bommel, F.1    Wunsche, T.2    Mauss, S.3
  • 61
    • 20144389653 scopus 로고    scopus 로고
    • Alberti A, Clumeck N, Collins S, et al. Short statement of the first European Consensus Conference on the treatment of chrortic hepatitis B and C in HIV co-infected patients. J Hepatol 2005;42:615-24
    • Alberti A, Clumeck N, Collins S, et al. Short statement of the first European Consensus Conference on the treatment of chrortic hepatitis B and C in HIV co-infected patients. J Hepatol 2005;42:615-24
  • 62
    • 17844401338 scopus 로고    scopus 로고
    • Anti-hepatitis B virus activity in HBV/HIV coinfected patients treated with tenofovir DF and lamivudine versus lamivudine alone; 144 week follow-up [abstrac 3308]
    • Bangkok;
    • Dore G, Cooper D, Pozniak AL, et al. Anti-hepatitis B virus activity in HBV/HIV coinfected patients treated with tenofovir DF and lamivudine versus lamivudine alone; 144 week follow-up [abstrac 3308]. XV International AIDS Conference; Bangkok; 2004
    • (2004) XV International AIDS Conference
    • Dore, G.1    Cooper, D.2    Pozniak, A.L.3
  • 63
    • 29444435439 scopus 로고    scopus 로고
    • Impact of tenofovir-containing antiretroviral therapy on chronic hepatitis B in a cohort co-infected with human immunodeficiency virus
    • Stephan C, Berger A, Carlebach A, et al. Impact of tenofovir-containing antiretroviral therapy on chronic hepatitis B in a cohort co-infected with human immunodeficiency virus. J Antimicrob Chemother 2005;56:1087-93
    • (2005) J Antimicrob Chemother , vol.56 , pp. 1087-1093
    • Stephan, C.1    Berger, A.2    Carlebach, A.3
  • 64
    • 44249122797 scopus 로고    scopus 로고
    • Marcellin P, Buti M, Kraxtev Z, et al. A randomized, double-blind, comparison of tenofovir DF versus adefovir dipivoxil for the treatment of HBeAg-negative chronic hepatitis B: Study GS-US-174-0102. Hepatology 2007;46:A-LB2
    • Marcellin P, Buti M, Kraxtev Z, et al. A randomized, double-blind, comparison of tenofovir DF versus adefovir dipivoxil for the treatment of HBeAg-negative chronic hepatitis B: Study GS-US-174-0102. Hepatology 2007;46:A-LB2
  • 65
    • 44249119832 scopus 로고    scopus 로고
    • Heathcote E, Gane E, DeMan R, et al. A randomized, double-blind, comparison of tenofovir DF versus adefovir dipivoxil for the treatment of HBeAg positive chronic hepatitis B: Study GS-US-174-0103. Hepatology 2007;46:A-LB6
    • Heathcote E, Gane E, DeMan R, et al. A randomized, double-blind, comparison of tenofovir DF versus adefovir dipivoxil for the treatment of HBeAg positive chronic hepatitis B: Study GS-US-174-0103. Hepatology 2007;46:A-LB6
  • 66
    • 10344230440 scopus 로고    scopus 로고
    • Pegylated-interferon-alfa-2b plus ribavirin vs standard interferon-alfa-2b plus ribavirin for the initial treatment of chronic hepatitis C in HIV-infected patients
    • Carat F, Bani-Sadr F, Pol S, et al. Pegylated-interferon-alfa-2b plus ribavirin vs standard interferon-alfa-2b plus ribavirin for the initial treatment of chronic hepatitis C in HIV-infected patients. JAMA 2004;292:2839-48
    • (2004) JAMA , vol.292 , pp. 2839-2848
    • Carat, F.1    Bani-Sadr, F.2    Pol, S.3
  • 67
    • 3343012408 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients
    • Torriani F, Rodriguez-Torres M, Rockstroh J, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients. N Engl J Med 2004;351:438-50
    • (2004) N Engl J Med , vol.351 , pp. 438-450
    • Torriani, F.1    Rodriguez-Torres, M.2    Rockstroh, J.3
  • 68
    • 34248592912 scopus 로고    scopus 로고
    • Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV international panel
    • Soriano V, Puori M, Sulkowski M, et al. Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV international panel. AIDS 2007;21:1073-89
    • (2007) AIDS , vol.21 , pp. 1073-1089
    • Soriano, V.1    Puori, M.2    Sulkowski, M.3
  • 69
    • 44249105631 scopus 로고    scopus 로고
    • Liver transaminase changes in HCV/HIV co-infected patients treated with tenofovir DF versus stavudine in combination with lamivudine and efavirenz
    • abstract 3307, Bangkok;
    • Pozniak AI, Staszewski S, Gallant JE, et al. Liver transaminase changes in HCV/HIV co-infected patients treated with tenofovir DF versus stavudine in combination with lamivudine and efavirenz [abstract 3307]. XV International AIDS Conference; Bangkok; 2004
    • (2004) XV International AIDS Conference
    • Pozniak, A.I.1    Staszewski, S.2    Gallant, J.E.3
  • 70
    • 3242694930 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate: Clinical pharmacology and pharmacokinetics
    • Kearney BP, Flaherty JF, Shah J. Tenofovir disoproxil fumarate: clinical pharmacology and pharmacokinetics. Clin Pharmacokinet 2004;43:595-612
    • (2004) Clin Pharmacokinet , vol.43 , pp. 595-612
    • Kearney, B.P.1    Flaherty, J.F.2    Shah, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.