Cholinergic submandibular effects and muscarinic receptor expression in blood vessels of the rat

Archives of Oral Biology

Volumn 53, Issue 7, 2008, Pages 605-616

  Ryberg, Anders T ^a   Selberg, Hanna ^a   Soukup, Ondrej ^a   Gradin, Kathryn ^a   Tobin, Gunnar ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Carotid artery; Jugular vein; Muscarinic receptor; Rat; Submandibular artery; Submandibular vein

Indexed keywords

CHOLINERGIC RECEPTOR STIMULATING AGENT; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR; VASODILATOR AGENT;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BLOOD VESSEL; DRUG EFFECT; MALE; METABOLISM; MUSCLE CONTRACTION; MUSCLE RELAXATION; RAT; SALIVA; SECRETION; SPRAGUE DAWLEY RAT; SUBMANDIBULAR GLAND; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASCULARIZATION;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD VESSELS; CHOLINERGIC AGONISTS; ENDOTHELIUM, VASCULAR; MALE; MUSCARINIC AGONISTS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M3; RECEPTORS, MUSCARINIC; SALIVA; SECRETORY PATHWAY; SUBMANDIBULAR GLAND; VASODILATOR AGENTS;

RATTUS;

EID: 43049172263     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2008.01.016     Document Type: Article

References (45)

1. Lundberg J.M. Pharmacology of cotransmission in the autonomic nervous system: integrative aspects on amines, neuropeptides, adenosine triphosphate, amino acids and nitric oxide. Pharmacol Rev 48 1 (1996) 113-178
2. Edwards A.V. Autonomic control of salivary blood flow. In: Garrett J., Ekström J., and Anderson L. (Eds). Glandular mechanisms of salivary secretion (1998), Karger, Basel 101-117
3. Izumi H. Nervous control of blood flow in the orofacial region. Pharmacol Ther 81 2 (1999) 141-161
4. Andersson P.O., Bloom S.R., Edwards A.V., and Jarhult J. Effects of stimulation of the chorda tympani in bursts on submaxillary responses in the cat. J Physiol 322 (1982) 469-483
5. Emmelin N., Garrett J.R., and Ohlin P. Neural control of salivary myoepithelial cells. J Physiol 196 2 (1968) 381-396
6. Edwards C.M., Corkery P.P., and Edwards A.V. Submandibular responses to stimulation of the parasympathetic innervation in anesthetized sheep. J Appl Physiol 95 4 (2003) 1598-1605
7. Lundberg J.M., Anggard A., and Fahrenkrug J. Complementary role of vasoactive intestinal polypeptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion. II. Effects of cholinergic antagonists and VIP antiserum. Acta Physiol Scand 113 3 (1981) 329-336
8. Kummer W., and Haberberger R. Extrinsic and intrinsic cholinergic systems of the vascular wall. Eur J Morphol 37 4/5 (1999) 223-226
9. Lundberg J.M., Anggard A., and Fahrenkrug J. Complementary role of vasoactive intestinal polypeptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion. Acta Physiol Scand 114 3 (1982) 329-337
10. Lundberg J.M., Anggard A., Fahrenkrug J., Hokfelt T., and Mutt V. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proc Natl Acad Sci USA 77 3 (1980) 1651-1655
11. Edwards A.V., Tobin G., Ekstrom J., and Bloom S.R. Nitric oxide and release of the peptide VIP from parasympathetic terminals in the submandibular gland of the anaesthetized cat. Exp Physiol 81 3 (1996) 349-359
12. Tobin G., Asztely A., Edwards A.V., Ekstrom J., Hakanson R., and Sundler F. Presence and effects of pituitary adenylate cyclase activating peptide in the submandibular gland of the ferret. Neuroscience 66 1 (1995) 227-235
13. Furchgott R.F. Endothelium-derived relaxing factor: discovery, early studies, and identification as nitric oxide. Biosci Rep 19 4 (1999) 235-251
14. Tobin G., Edwards A.V., Bloom S.R., and Ekstrom J. Nitric oxide in the control of submandibular gland function in the anaesthetized ferret. Exp Physiol 82 5 (1997) 825-836
15. Edwards A.V., and Garrett J.R. Nitric oxide-related vasodilator responses to parasympathetic stimulation of the submandibular gland in the cat. J Physiol 464 (1993) 379-392
16. Hanna S.J., and Edwards A.V. The role of nitric oxide in the control of protein secretion in the parotid gland of anaesthetized sheep. Exp Physiol 83 4 (1998) 533-544
17. Anderson L.C., and Garrett J.R. Neural regulation of blood flow in the rat submandibular gland. Eur J Morphol 36 Suppl. (1998) 213-218
18. Tobin G., Giglio D., and Gotrick B. Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats. Auton Neurosci 100 1/2 (2002) 1-9
19. van Zwieten P.A., Hendriks M.G., Pfaffendorf M., Bruning T.A., and Chang P.C. The parasympathetic system and its muscarinic receptors in hypertensive disease. J Hypertens 13 10 (1995) 1079-1090
20. Ayer A., Antic V., Dulloo A.G., Van Vliet B.N., and Montani J.P. Hemodynamic consequences of chronic parasympathetic blockade with a peripheral muscarinic antagonist. Am J Physiol Heart Circ Physiol 293 (2007) H1265-H1272
21. Eglen R.M., and Watson N. Selective muscarinic receptor agonists and antagonists. Pharmacol Toxicol 78 2 (1996) 59-68
22. Rabe K.F., Dent G., and Magnussen H. Hydrogen peroxide contracts human airways in vitro: role of epithelium. Am J Physiol 269 3 Pt 1 (1995) L332-L338
23. Arevalo-Leon L.E., Gallardo-Ortiz I.A., Urquiza-Marin H., and Villalobos-Molina R. Evidence for the role of alpha1D- and alpha1A-adrenoceptors in contraction of the rat mesenteric artery. Vascul Pharmacol 40 2 (2003) 91-96
24. Tobin G., Ryberg A.T., Gentle S., and Edwards A.V. Distribution and function of muscarinic receptor subtypes in the ovine submandibular gland. J Appl Physiol 100 4 (2006) 1215-1223
25. Stojic D., Pesic S., Radenkovic M., Popovic-Roganovic J., Pesic Z., and Grbovic L. Responses of the human submandibular artery to ACh and VIP. J Dent Res 86 6 (2007) 565-570
26. Sendao Oliveira A.P., and Bendhack L.M. Relaxation induced by acetylcholine involves endothelium-derived hyperpolarizing factor in 2-kidney 1-clip hypertensive rat carotid arteries. Pharmacology 72 4 (2004) 231-239
27. Cohen M.L., and Wiley K.S. Rat jugular vein relaxes to norepinephrine, phenylephrine and histamine. J Pharmacol Exp Ther 205 2 (1978) 400-409
28. Deighan C., Methven L., Naghadeh M.M., Wokoma A., Macmillan J., Daly C.J., et al. Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice. Br J Pharmacol 144 4 (2005) 558-565
29. Furchgott R.F., and Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288 5789 (1980) 373-376
30. Eglen R.M., and Nahorski S.R. The muscarinic M(5) receptor: a silent or emerging subtype?. Br J Pharmacol 130 1 (2000) 13-21
31. Anderson L.C., Martin D.J., Phillips D.L., Killpack K.J., Bone S.E., and Rahimian R. The influence of gender on parasympathetic vasodilatation in the submandibular gland of the rat. Exp Physiol 91 2 (2006) 435-444
32. Lung M.A. Autonomic nervous control of venous pressure and secretion in submandibular gland of anesthetized dogs. Am J Physiol 275 2 Pt 1 (1998) G331-G341
33. Walch L., Brink C., and Norel X. The muscarinic receptor subtypes in human blood vessels. Therapie 56 3 (2001) 223-226
34. Pujol Lereis V.A., Hita F.J., Gobbi M.D., Verdi M.G., Rodriguez M.C., and Rothlin R.P. Pharmacological characterization of muscarinic receptor subtypes mediating vasoconstriction of human umbilical vein. Br J Pharmacol 147 5 (2006) 516-523
35. Berggreen E., Wiig H., and Heyeraas K.J. Blood flow and interstitial fluid pressure in the rat submandibular gland during changes in perfusion. J Dent Res 82 11 (2003) 899-902
36. Tonder K.J., and Kvinnsland I. Micropuncture measurements of interstitial fluid pressure in normal and inflamed dental pulp in cats. J Endod 9 3 (1983) 105-109
37. Berggreen E., and Wiig H. Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion. Am J Physiol Heart Circ Physiol 290 4 (2006) H1460-H1468
38. Asztely A., Havel G., and Ekstrom J. Vascular protein leakage in the rat parotid gland elicited by reflex stimulation, parasympathetic nerve stimulation and administration of neuropeptides. Regul Pept 77 1-3 (1998) 113-120
39. Ryberg A.T., Warfvinge G., Axelsson L., Soukup O., Gotrick B., and Tobin G. Expression of muscarinic receptor subtypes in salivary glands of rats, sheep and man. Arch Oral Biol 53 1 (2008) 66-74
40. Ohtani O., Ohtsuka A., Lipsett J., and Gannon B. The microvasculature of rat salivary glands. A scanning electron microscopic study. Acta Anat (Basel) 115 4 (1983) 345-356
41. Kawashima K., and Fujii T. Extraneuronal cholinergic system in lymphocytes. Pharmacol Ther 86 1 (2000) 29-48
42. Kawashima K., Watanabe N., Oohata H., Fujimoto K., Suzuki T., Ishizaki Y., et al. Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells. Neurosci Lett 119 2 (1990) 156-158
43. Ekstrom J., and Tobin G. Protein secretion in salivary glands of cats in vivo and in vitro in response to vasoactive intestinal peptide. Acta Physiol Scand 140 1 (1990) 95-103
44. Ekstrom J., and Tobin G. Secretion of protein from salivary glands in the ferret in response to vasoactive intestinal peptide. J Physiol 415 (1989) 131-141
45. Tobin G. Presynaptic muscarinic M1 and M2 receptor modulation of auriculotemporal nerve transmission in the rat. J Auton Nerv Syst 72 1 (1998) 61-71