The role of nitric oxide in the control of protein secretion in the parotid gland of anaesthetized sheep

Experimental Physiology

Volumn 83, Issue 4, 1998, Pages 533-544

  Hanna, S J ^a   Edwards, A V ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROLYTE; N(G) NITRO DEXTRO ARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; SODIUM;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROLYTE TRANSPORT; GENERAL ANESTHESIA; NERVE STIMULATION; NONHUMAN; PARASYMPATHETIC INNERVATION; PAROTID GLAND; PROTEIN SECRETION; SALIVATION; SHEEP; SYMPATHETIC INNERVATION;

EID: 0031927085     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.1998.sp004136     Document Type: Article

References (29)

1. ANDERSSON, P.-O., BLOOM, S. R., EDWARDS, A. V. & JÄRHULT, J. (1982). Effects of stimulation of the chorda tympani in bursts on submaxillary responses in the cat. Journal of Physiology 322, 469-483.
2. BLOOM, S. R. & EDWARDS, A. V. (1980). Vasoactive intestinal peptide in relation to atropine resistant vasodilatation in the submaxillary gland of the cat. Journal of Physiology 300, 41-53.
3. BUCKLE, A. D., PARKER, S. J., BLOOM, S. R. & EDWARDS, A. V. (1995). The role of nitric oxide in the control of protein secretion in the submandibular gland of the cat. Experimental Physiology 80, 1019-1030.
4. DUNÉR-ENGSTRÖM, M., LARSSON, O., FREDHOLM, B. B., LUNDBLAD, L., FAHRENKRUG, J. & LUNDBERG, J. M. (1992). Effects of acute and long-term atropine treatment on levels, release and response to VIP and PHI in the submandibular gland of cat and rat. Acta Physiologica Scandinavica 146, 357-367.
5. EDWARDS, A. V. & GARRETT, J. R. (1993). Nitric oxide-related vasodilator responses to parasympathetic stimulation of the submandibular gland in the cat. Journal of Physiology 464, 379-392.
6. EDWARDS, A. V. & TITCHEN, D. A. (1991). Synergism in the autonomic control of secretion of protein from the parotid gland in anaesthetized sheep. Journal of Physiology 438, 248P.
7. EDWARDS, A. V. & TITCHEN, D. A. (1992). Synergism in the autonomie regulation of parotid secretion of protein in the sheep. Journal of Physiology 451, 1-15.
8. EDWARDS, A. V., TOBIN, G., EKSTRÖM, J. & BLOOM, S. R. (1996). Nitric oxide and release of the peptide VIP from parasympathetic nerve terminals in the submandibular gland of the anaesthetized cat. Experimental Physiology 81, 349-359.
9. EKSTRÖM, J., MÅNSSON, B. & TOBIN, G. (1983). Vasoactive intestinal peptide evoked secretion of fluid and protein from rat salivary glands and the development of supersensitivity. Acta Physiologica Scandinavica 119, 169-175.
10. EKSTRÖM, J. & TOBIN, G. (1989). Secretion of protein from salivary glands in the ferret in response to vasoactive intestinal peptide. Journal of Physiology 415, 131-141.
11. EKSTRÖM, J. & TOBIN, G. (1990). Protein secretion in salivary glands of cats in vivo and in vitro in response to vasoactive intestinal peptide. Acta Physiologica Scandinavica 140, 95-103.
12. FAZEKAS, A., GAZELIUS, B., EDWALL, B., THEODORSSON-NORHEIM, E., BLOMQUIST, L. & LUNDBERG, J. M. (1987). VIP and noncholinergic vasodilation in rabbit submandibular gland. Peptides 8, 13-20.
13. GRIDER, J. R. (1993). Interplay of VIP and nitric oxide in regulation of the descending relaxation phases of peristalsis. American Journal of Physiology 264, G334-340.
14. GRIDER, J. R., MURTHY, K. S., JIN, J.-G. & MAHKLOUF, G. M. (1992). Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release. American Journal of Physiology 262, G774-778.
15. ITOH, N. OBATA, K., YANAIHARA, N. & OKAMOTO, H. (1983). Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27. Nature 304, 547-549.
16. LUNDBERG, J. M. ÄNGGÅRD, A., FAHRENKRUG, J., HÖKFELT, T. & MUTT, V. (1980). Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the USA 77, 1651-1655.
17. LUNDBERG, J. M., FAHRENKRUG, J., HÖKFELT, T., MARTLING, C.-R., LARSSON, O., TATEMOTO, K. & ÄNGGÅRD, A. (1984a). Co-existence of peptide HI (PHI) and VIP in nerves regulating bloodflow and bronchial smooth muscle tone in various mammals including man. Peptides 5, 593-606.
18. LUNDBERG, J. M., FAHRENKRUG, J., LARSSON, O. & ÄNGGÅRD, A. (1984b). Corelease of vasoactive intestinal polypeptide and peptide histidine isoleucine in relation to atropine resistant vasodilatation in cat submandibular salivary gland. Neuroscience Letters 52, 27-42.
19. MIRFENDERESKI, S., TOBIN, G., HÅKANSON, R. & EKSTRÖM, J. (1997). Pituitary adenylate cyclase activating peptide (PACAP) in salivary glands of the rat: Origin, and secretory and vascular effects. Acta Physiologica Scandinavica 160, 15-22.
20. MODIN, A., WEITZBERG, E. & LUNDBERG, J. M. (1994). Nitric oxide regulates peptide release from parasympathetic nerve terminals and vascular reactivity to vasoactive intestinal polypeptide in vivo. European Journal of Pharmacology 261, 185-197.
21. REID, A. M. & TITCHEN, D. A. (1985). Effects of vasoactive intestinal polypeptide on ovine parotid and submandibular saliva. Proceedings of The Australian Physiological and Pharmacological Society 16, 27P.
22. REID, A. M. & TITCHEN, D. A. (1988). Atropine-resistant secretory responses of the ovine parotid gland to reflex and direct parasympathetic stimulation. Quarterly Journal of Experimental Physiology 73, 413-424.
23. TOBIN, G., ASZTÉLY, A., EDWARDS, A. V., EKSTRÖM, J., HÅKANSON, R. & SUNDLER, F. (1995). Presence and effects of pituitary adenylate cyclase activating peptide in the submandibular gland of the ferret. Neuroscience 66, 227-235.
24. TOBIN, G., EDWARDS, A. V., BLOOM, S. R. & EKSTRÖM, J. (1997). Nitric oxide in the control of submandibular function in the anaesthetized ferret. Experimental Physiology 82, 825-836.
25. TOBIN, G., EKSTRÖM, J., BLOOM, S. R. & EDWARDS, A. V. (1991a). Atropine-resistant submandibular responses to stimulation of the parasympathetic innervation in the anaesthetized ferret. Journal of Physiology 437, 327-339.
26. TOBIN, G., EKSTRÖM, J. & EDWARDS, A. V. (1991b). Submandibular responses to stimulation of the parasympathetic innervation in the anaesthetized ferret. Journal of Physiology 431, 417-425.
27. TOBIN, G., LUTS, A., SUNDLER, F. & EKSTRÖM, J. (1990). VIP-containing nerve fibres in the submandibular gland of the dog and protein secretion in vitro in response to VIP. Regulatory Peptides 29, 173-177.
28. WATHUTA, E. M. (1986). The distribution of vasoactivc intestinal polypeptide-like, substance P-like and bombesin-like immunoreactivity in the digestive system of the sheep. Quarterly Journal of Experimental Physiology 71, 615-631.
29. WRIGHT, R. D., BLAIR WEST, J. R., GIBSON, A. P. & SHULKES, A. (1991). Evidence against the involvement of vasoactive intestinal peptide in ovine parotid secretion and blood flow. Clinical and Experimental Pharmacology and Physiology 18, 469-474.