Development of a cell death-based method for the screening of nuclear factor-κB inhibitors

Journal of Immunological Methods

Volumn 335, Issue 1-2, 2008, Pages 126-131

  Chopra, Puneet ^a   Bajpai, Malini ^a   Dastidar, Sunanda G ^a   Ray, Abhijit ^a  

^a RANBAXY RESEARCH LABORATORIES   (India)

Author keywords

Cell death assay; Electrophoretic mobility shift assay; High throughput screening; Nuclear factor kappa B

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 (2,6 DICHLOROPHENYL) 2 (2,4 DIFLUOROPHENYLTHIO)PYRIMIDO[1,6 B]PYRIDAZIN 6 ONE; GENISTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRROLIDINE DITHIOCARBAMATE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DNA BINDING; DNA FRAGMENTATION; DRUG EFFECT; DRUG INHIBITION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BIOLOGICAL ASSAY; CASPASES; CELL SURVIVAL; DNA FRAGMENTATION; DRUG EVALUATION, PRECLINICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENISTEIN; MACROPHAGES; MICE; NF-KAPPA B; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRROLIDINES; SULFONES; THIOCARBAMATES; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

MURINAE;

EID: 43049159562     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2008.02.016     Document Type: Article

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