Facile synthesis of novel mutual derivatives of nucleosides and pyrimidines by regioselectively chemo-enzymatic protocol

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 9, 2008, Pages 5181-5188

  Qian, Xueqi ^a   Liu, Bokai ^a   Wu, Qi ^a   Lv, Deshui ^a   Lin, Xian Fu ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Chemo enzymatic; Cytarabine; Pyrimidine; Regioselectivity; Ribavirin; Transesterification

Indexed keywords

5' O [1 (1 THYMIDINE) ETHYL VINYL ADIPATE] CYTARABINE; 5' O [1 (1 THYMIDINE) ETHYL VINYL ADIPATE] RIBAVIRIN; 5' O [1 (1 THYMIDINE) ETHYL VINYL SEBACATE] CYTARABINE; 5' O [1 (1 THYMIDINE) ETHYL VINYL SEBACATE] RIBAVIRIN; 5' O [1 (1 URACIL) ETHYL VINYL ADIPATE] CYTARABINE; 5' O [1 (1 URACIL) ETHYL VINYL ADIPATE] RIBAVIRIN; 5' O [1 (1 URACIL) ETHYL VINYL SEBACATE] CYTARABINE; 5' O [1 (1 URACIL) ETHYL VINYL SEBACATE] RIBAVIRIN; 5' O [1 [1 (5 FLUOROURACIL)] ETHYL VINYL ADIPATE] CYTARABINE; 5' O [1 [1 (5 FLUOROURACIL)] ETHYL VINYL ADIPATE] RIBAVIRIN; 5' O [1 [1 (5 FLUOROURACIL)] ETHYL VINYL SEBACATE] CYTARABINE; 5' O [1 [1 (5 FLUOROURACIL)] ETHYL VINYL SEBACATE] RIBAVIRIN; ANTIVIRUS AGENT; DIMETHYL SULFOXIDE; NUCLEOSIDE DERIVATIVE; POTASSIUM CARBONATE; PYRIMIDINE DERIVATIVE;

ACYLATION; ADDITION REACTION; ARTICLE; CANDIDA ANTARCTICA; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; IMMOBILIZATION; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACYLATION; CANDIDA; CARBONATES; CATALYSIS; CYTARABINE; ENZYMES, IMMOBILIZED; LIPASE; MOLECULAR STRUCTURE; NUCLEOSIDES; POTASSIUM; PYRIMIDINES; RIBAVIRIN; STEREOISOMERISM;

CANDIDA ANTARCTICA;

EID: 43049150100     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.03.012     Document Type: Article

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