Infrared laser light further improves bone healing when associated with bone morphogenetic proteins and guided bone regeneration: An in vivo study in a rodent model

Photomedicine and Laser Surgery

Volumn 26, Issue 2, 2008, Pages 167-174

  Pinheiro, Antonio Luiz B ^a,b   Gerbi, Marleny E Martinez ^c   Ponzi, Elizabeth Arruda Carneiro ^c   Ramalho, Luciana Maria Pedreira ^a   Marques, Aparecida M C ^a,b   Carvalho, Carolina Montagn ^a,b   Santos, Rafael De Carneiro ^a,b   Oliveira, Priscila Chagas ^a,b   Nóia, Manuela ^a,b  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b INSTITUTO DE PESQUISA E DESENVOLVIMENTO   (Brazil)

^c FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; GRAFTS; LIGHT MODULATION; OPTICAL MICROSCOPY; PROTEINS; SURGERY;

GUIDED BONE REGENERATION; MORPHOGENETIC PROTEINS; PHOTOBIOMODULATION;

LASER BEAMS;

BONE MORPHOGENETIC PROTEIN; COLLAGEN FIBER; EOSIN; HEMATOXYLIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GRAFT; BONE REGENERATION; BONE REMODELING; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FRACTURE HEALING; IN VIVO STUDY; INFRARED RADIATION; LASER SURGERY; MALE; MICROSCOPY; NONHUMAN; RAT; SURGICAL TECHNIQUE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; FEMALE; FEMUR; GUIDED TISSUE REGENERATION; LASER THERAPY; MALE; RATS; RATS, WISTAR;

EID: 43049144282     PISSN: 15495418     EISSN: None     Source Type: Journal    
DOI: 10.1089/pho.2007.2027     Document Type: Article

References (30)

1. Pinheiro, A.L.B., and Gerbi, M.E.M.M. (2006). Photobioenginnering of the bone repair process. Photomed. Laser Surg. 24,169-178.
2. Pinheiro, A.L.B., Limeira Júnior, F.A., Gerbi, M.E.M.M., et al. (2003). Effect of 830 nm laser light on the repair of bone defects grafted with inorganic bovine bone and decalcified cortical osseous membrane. J. Clin. Laser Med. Surg. 21, 383-388.
3. Limeira Junior, F.A. (2004). Estudo do Reparo ósseo após irradiação com laser 830nm associado a implante de hidroxiapatita e membrana de osso [Ph.D. thesis]. Universidade Federal da Bahia, Salvador-BA, Brazil.
4. Gerbi, M.E.M.M., Pinheiro, A.L.B., Marzola, C., et al. (2005). Assessment of bone repair associated with the use of organic bovine bone and membrane irradiated at 830 nm. Photomed. Laser Surg. 23, 382-388.
5. Gerbi, M.E.M.M. (2004). Avaliação da eficácia do laser de 830 nm no reparo ósseo de feridas cirúrgicas associadas ou não a implante de proteinas morfogenéticas ósseas e membrana biológica [Ph.D. thesis]. Universidade Federal da Bahia, Salvador-BA, Brazil.
6. Pinheiro, A.L.B., and Gerbi M.E.M.M. (2004). Laserterapia: Uma visão atual sobre as aplicações clínicas na prática implantodôntica, in: Implantes Osseointegrados - Inovando Soluções. M.R.M. Querido, Y.L. Fan, (eds.). São Paulo: Artes Médicas, pp. 283-303.
7. Pontual, M.A.B., and Magiani, R.S. (2004). Plasma Rico em Plaquetas PRP e Fatores de Crescimento das Pesquisas Científicas à Clínica Odontológica. São Paulo: Santos, p. 308.
8. Marzola, C., Toledo Filho, J.L., Zorzeto, D.L.G., and Pastori, C.M. (1996). Implantes de Bioapatita + Osseobond + Membrana Reabsorvível Dentoflex + Aglutinante Dentoflex. Apresentação de casos clínico-cirúrgicos. Rev. Bras. Ciênc. Estomatol. 1, 51-63.
9. Pinheiro, A.L.B., Oliveira, M.A.M., and Martins, P.P.M. (2001). Biomodulação da cicatrização óssea pós-implantar com o uso da laserterapia não-cirúrgica: Estudo por microscopia eletrônica de varredura. Rev FOUFBA. 22, 12-19.
10. Silva Júnior, A.N., Pinheiro, A.L.B., Oliveira, M.G., et al. (2002). Computerized morphometric assessment of the effect of low-level laser therapy on bone repair. J. Clin. Laser Med. Surg. 20, 83-87.
11. Pinheiro, A.L.B., Limeira Júnior, F.A., Gerbi, M.E.M.M., et al. (2003). Effect of low level laser therapy on the repair of bone defects grafted with inorganic bovine bone. Braz. Dent. J. 14, 177-181.
12. Lopes, C.B., Pinheiro, A.L.B., Sathaiah, S., et al. (2005). Infrared laser light reduces loading time of dental implants: A Raman spectroscopic study. Photomed. Laser Surg. 23, 27-31.
13. Weber, J.B.B., Pinheiro, A.L.B., Oliveira, M.G., Oliveira, F.A.M., and Ramalho, L.M.P. (2006). Laser therapy improves bone healing of bone defects submitted to autologous bone graft. Photomed. Laser Surg. 24, 38-44.
14. Tuner, J., and Hode, L. (2004). The Laser Therapy Handbook. Grängesberg, Sweden: Prima Books, p. 589.
15. Schultze-Mosgau, S., Lehner, B., Rodel, F., et al. (2005). Expression of bone morphogenic protein 2/4, transforming growth factor-beta1, and bone matrix protein expression in healing area between vascular tibia grafts and irradiated bone - experimental model of osteonecrosis. Int. J. Radiat. Oncol. Biol. Phys. 15, 1189-1196.
16. Si, X., Jin, Y., Yang, L., et al. (1997). Expression of BMP-2 and TGF-beta 1 mRNA during healing of the rabbit mandible. Eur. J. Oral Sci. 105, 325-330.
17. Paccione, M.F., Mehrara, B.J., and Warren, S.M. (2001). Rat mandibular distraction osteogenesis: Latency, rate, and rhythm determine the adaptive response. J. Craniofac. Surg. 12, 175-182.
18. Schultze-Mosgau, T., Blaese, M., and Grabenbauer, G.G. (2004). Smad-3 and Smad-7 expression following anti-transforming growth factor beta 1 (TGF-β1)-treatment in irradiated rat tissue. Radiother. Oncol. 70, 249-259.
19. Arnold, M., Stas, P., and Kummermehr, J., et al. (1998). Radiation-induced impairment of bone healing in the rat femur: Effects of radiation dose, sequence and interval between surgery and irradiation. Radiother. Oncol. 48, 259-265.
20. Roth, N.M., Sontag, M.R., and Kiani, M.F. (1999). Early effects of ionizing radiation on the microvascular networks in normal tissue. Radiat. Res. 151, 270-277.
21. Koelbl, A., Knaus, P., Pohl, F., et al. (2001). Radiation-induced reduction of BMP-induced proteoglycan synthesis in an embryonal mesenchymal tissue equivalent using the chicken "limb bud" test. Strahlenther Onkol. 177, 432-436.
22. Pohl, F., Hassel, S., and Nohe, A, et al. (2003). Radiation-induced suppression of the BMP2 signal transduction pathway in the pluripotent mesenchymal cell line C2C12: An in vitro model for prevention of heterotopic ossification by radiotherapy. Radiat. Res. 159, 345-350.
23. Zwijsen, A., Verschueren, K., and Huylebroeck, D. (2003). New intracellular components of bone morphogenetic protein/Smad signaling cascades. FEBS Lett. 546, 133-139.
24. Howard, B.K., Brown, K.R., Leach, J.L., et al. (1998). Osteoinduction using bone morphogenic protein in irradiated tissue. Arch. Otolaryngol. Head Neck Surg. 124, 985-988.
25. Chen, Y., Luk, K.D., Cheung, K.M., et al. (2003). Gene therapy for new bone formation using adeno-associated viral bone morphogenetic protein-2 vectors. Gene Ther. 10, 1345-1353.
26. Gugala, Z., Olmsted-Davis, E.A., Gannon, F.H., et al. (2003). Osteoinduction by ex vivo adenovirus-mediated BMP2 delivery is independent of cell type. Gene Ther. 10, 1289-1296.
27. Luk, K.D., Chen, Y., Cheung, K.M., et al. (2003). Adeno-associated virus-mediated bone morphogenetic protein-4 gene therapy for in vivo bone formation. Biochem. Biophys. Res. Commun. 308, 636-645.
28. Yuan, B., and Liu, Z. (2007). Treatment of osteonecrosis of the femoral head: Combination of operation and multiple cellular mediators. Med. Hypotheses. 68, 502-505.
29. Jones, A.L., Bucholz, R.W., Bosse, M.J., et al. (2006). Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J. Bone Joint Surg. Am. 88, 1431-1441.
30. Alexandrakis, M.G., Passam, F.H., Pappa, C.A. et al. (2005). Relation between bone marrow angiogenesis and serum levels of angiogenin in patients with myelodysplastic syndromes. Leuk. Res. 29, 41-46.