Aplicyanins A-F, new cytotoxic bromoindole derivatives from the marine tunicate Aplidium cyaneum

Tetrahedron

Volumn 64, Issue 22, 2008, Pages 5119-5123

  Reyes, Fernando ^a   Fernández, Rogelio ^a   Rodríguez, Alberto ^a   Francesch, Andrés ^a   Taboada, Sergi ^b   Ávila, Conxita ^b   Cuevas, Carmen ^a  

^a PHARMAMAR S A   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Antarctic tunicates; Antimitotic; Bromoindole; Cytotoxicity; Marine metabolites

Indexed keywords

ANTIMITOTIC AGENT; APLICYANIN A; APLICYANIN B; APLICYANIN C; APLICYANIN D; APLICYANIN E; APLICYANIN F; BROMOINDOLE DERIVATIVE; INDOLE DERIVATIVE;

ARTICLE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; MARINE SPECIES; PRIORITY JOURNAL;

APLIDIUM; UROCHORDATA;

EID: 43049140842     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.03.060     Document Type: Article

References (19)

1. Zubía E., Ortega M.J., and Salvá J. Mini-Rev. Org. Chem. 2 (2005) 389
2. Rinehart K. L. U.S. Patent 5,294,603, 1994;
3. Chem. Abstr. 121 (1994) 887
4. Jimeno J., Faircloth G., Fernández Sousa-Faro J.M., Scheuer P., and Rinehart K. Mar. Drugs 2 (2004) 14
5. Galinis D.L., McKee T.C., Pannell L.K., Cardellina II J.H., and Boyd M.R. J. Org. Chem. 62 (1997) 8968
6. McKee T.C., Galinis D.L., Pannell L.K., Cardellina II J.H., Laakso J., Ireland C.M., Murray L., Capon R.J., and Boyd M.R. J. Org. Chem. 63 (1998) 7805
7. Carroll A.R., Bowden B.F., and Coll J.C. Aust. J. Chem. 46 (1993) 825
8. Copp B.R., Blunt J.W., Kurz L., Schatzman R.C., and Munro M.H.G. Tetrahedron Lett. 28 (1989) 3703
9. Kim J., Pordesimo E.O., Toth S.I., Schmitz F.J., and van Altena I. J. Nat. Prod. 56 (1993) 1813
10. Garrido L., Zubía E., Ortega M.J., and Salvá J. J. Org. Chem. 68 (2003) 293
11. Aiello A., Fattorusso E., Luciano P., Menna M., Esposito G., Iuvone T., and Pala D. Eur. J. Org. Chem. (2003) 898
12. Aiello A., Fattorusso E., Luciano P., Macho A., Menna M., and Muñoz E. J. Med. Chem. 48 (2005) 3410
13. Franco L.H., Joffé E.B.K., Puricelli L., Tatian M., Seldes A.M., and Palermo J.A. J. Nat. Prod. 61 (1998) 1130
14. Seldes A.M., Brasco M.F.R., Franco L.H., and Palermo J.A. Nat. Prod. Res. 21 (2007) 555
15. Aiello A., Borrelli F., Capasso R., Fattorusso E., Luciano P., and Menna M. Bioorg. Med. Chem. Lett. 13 (2003) 4481
16. Gompel M., Leost M., Joffé E.B.K., Puricelli L., Franco L.H., Palermo J., and Meijer L. Bioorg. Med. Chem. Lett. 14 (2004) 1703
17. Narkowickz K.C., Blackman A.J., Lacey E., Gill J.H., and Heiland K. J. Nat. Prod. 65 (2002) 938
18. Makarieva T.N., Dimitrenok A.S., Dimitrenok P.S., Grebnev B.B., and Stonik V.A. J. Nat. Prod. 64 (2001) 1559
19. Skehan P., Storeng R., Scudiero D., Monks A., McMahon J., Vistica D., Warren J.T., Bokesch H., Kenney S., and Boyd M.R. J. Natl. Cancer Inst. 82 (1990) 1107