메뉴 건너뛰기




Volumn 51, Issue 6, 2008, Pages 1018-1024

Evidence that autonomic mechanisms contribute to the adaptive increase in insulin secretion during dexamethasone-induced insulin resistance in humans

Author keywords

Autonomic nerves; Dexamethasone; Humans; Insulin secretion; Parasympathetic nerves; Trimethaphan

Indexed keywords

ARGININE; DEXAMETHASONE; GLUCOSE; INSULIN; TRIMETAPHAN;

EID: 43049135469     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-0995-y     Document Type: Article
Times cited : (24)

References (37)
  • 1
    • 0019810028 scopus 로고
    • Physiologic evaluation of factors controlling glucose tolerance in man. Measurements of insulin sensitivity and B-cell glucose sensitivity from the response to intravenous glucose
    • Bergman RN, Phillips LS, Cobelli C (1981) Physiologic evaluation of factors controlling glucose tolerance in man. Measurements of insulin sensitivity and B-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68:1456-1467
    • (1981) J Clin Invest , vol.68 , pp. 1456-1467
    • Bergman, R.N.1    Phillips, L.S.2    Cobelli, C.3
  • 2
    • 0027375768 scopus 로고
    • Quantification of the relationship between insulin sensitivity and b-cell function in human subjects. Evidence for a hyperbolic function
    • Kahn SE, Prigeon RL, McCulloch DK et al (1993) Quantification of the relationship between insulin sensitivity and b-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42:1663-1672
    • (1993) Diabetes , vol.42 , pp. 1663-1672
    • Kahn, S.E.1    Prigeon, R.L.2    McCulloch, D.K.3
  • 3
    • 12744263199 scopus 로고    scopus 로고
    • Islet adaptation to insulin resistance: Mechanisms and implications for intervention
    • Ahrén B, Pacini G (2005) Islet adaptation to insulin resistance: mechanisms and implications for intervention. Diabetes Obes Metab 7:2-8
    • (2005) Diabetes Obes Metab , vol.7 , pp. 2-8
    • Ahrén, B.1    Pacini, G.2
  • 4
    • 0029816099 scopus 로고    scopus 로고
    • Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance
    • Larsson H, Ahrén B (1996) Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance. Diabetologia 39:1099-1107
    • (1996) Diabetologia , vol.39 , pp. 1099-1107
    • Larsson, H.1    Ahrén, B.2
  • 5
    • 0030716888 scopus 로고    scopus 로고
    • Impaired adaptation of first-phase insulin secretion in postmenopausal women with glucose intolerance
    • Ahrén B, Pacini G (1997) Impaired adaptation of first-phase insulin secretion in postmenopausal women with glucose intolerance. Am J Physiol 273:E701-E707
    • (1997) Am J Physiol , vol.273
    • Ahrén, B.1    Pacini, G.2
  • 6
    • 0032742992 scopus 로고    scopus 로고
    • The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
    • Weyer C, Bogardus C, Mott DM, Pratley RE (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104:787-794
    • (1999) J Clin Invest , vol.104 , pp. 787-794
    • Weyer, C.1    Bogardus, C.2    Mott, D.M.3    Pratley, R.E.4
  • 7
    • 0024538602 scopus 로고
    • Increased β-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance
    • Kahn SE, Beard JC, Schwartz MW et al (1989) Increased β-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes 38:562-568
    • (1989) Diabetes , vol.38 , pp. 562-568
    • Kahn, S.E.1    Beard, J.C.2    Schwartz, M.W.3
  • 8
    • 0032786955 scopus 로고    scopus 로고
    • Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity
    • Larsson H, Ahrén B (1999) Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity. Diabetologia 42:936-943
    • (1999) Diabetologia , vol.42 , pp. 936-943
    • Larsson, H.1    Ahrén, B.2
  • 9
    • 0031683543 scopus 로고    scopus 로고
    • Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
    • Dobbins RI, Chester MW, Daniels MB et al (1998) Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans. Diabetes 47:1613-1618
    • (1998) Diabetes , vol.47 , pp. 1613-1618
    • Dobbins, R.I.1    Chester, M.W.2    Daniels, M.B.3
  • 10
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou VP, Grill VE (1994) Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870-876
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, V.P.1    Grill, V.E.2
  • 11
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion-implications for health and disease
    • Ahrén B (2000) Autonomic regulation of islet hormone secretion-implications for health and disease. Diabetologia 43:393-410
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahrén, B.1
  • 12
    • 33845543747 scopus 로고    scopus 로고
    • Neuropeptides and the regulation of islet function
    • Suppl 2
    • Ahrén B, Wierup N, Sundler F (2006) Neuropeptides and the regulation of islet function. Diabetes 55(Suppl 2):S98-S107
    • (2006) Diabetes , vol.55
    • Ahrén, B.1    Wierup, N.2    Sundler, F.3
  • 13
    • 0020057920 scopus 로고
    • Modulation of basal insulin secretion in the obese, hyperglycemic, mouse
    • Ahrén B, Lundquist I (1982) Modulation of basal insulin secretion in the obese, hyperglycemic, mouse. Metabolism 31:172-179
    • (1982) Metabolism , vol.31 , pp. 172-179
    • Ahrén, B.1    Lundquist, I.2
  • 14
    • 0020742043 scopus 로고
    • Hyperinsulinemia of preobese and obese fa/fa rats is partly vagus nerve mediated
    • Rohner-Jeanrenaud F, Hochstrasser AC, Jeanrenaud B (1983) Hyperinsulinemia of preobese and obese fa/fa rats is partly vagus nerve mediated. Am J Physiol 244:E317-E322
    • (1983) Am J Physiol , vol.244
    • Rohner-Jeanrenaud, F.1    Hochstrasser, A.C.2    Jeanrenaud, B.3
  • 15
    • 0032768774 scopus 로고    scopus 로고
    • Increased insulin secretion and normalisation of glucose tolerance by cholinergic agonism in high-fat fed C57BL/6J mice
    • Ahrén B, Sauerberg P, Thomsen C (1999) Increased insulin secretion and normalisation of glucose tolerance by cholinergic agonism in high-fat fed C57BL/6J mice. Am J Phyisol 277:E93-E102
    • (1999) Am J Phyisol , vol.277
    • Ahrén, B.1    Sauerberg, P.2    Thomsen, C.3
  • 16
    • 0017948650 scopus 로고
    • Vagal, cholinergic regulation of pancreatic polypeptide secretion
    • Schwartz TW, Holst JJ, Fahrenkrug J (1978) Vagal, cholinergic regulation of pancreatic polypeptide secretion. J Clin Invest 61:781-789
    • (1978) J Clin Invest , vol.61 , pp. 781-789
    • Schwartz, T.W.1    Holst, J.J.2    Fahrenkrug, J.3
  • 17
    • 0024437744 scopus 로고
    • The contribution of the autonomic nervous system to changes of glucagon and insulin secretion during hypoglycaemic stress
    • Havel PJ, Taborsky GJ Jr (1989) The contribution of the autonomic nervous system to changes of glucagon and insulin secretion during hypoglycaemic stress. Endocr Rev 10:332-350
    • (1989) Endocr Rev , vol.10 , pp. 332-350
    • Havel, P.J.1    Taborsky Jr., G.J.2
  • 18
    • 0035116921 scopus 로고    scopus 로고
    • Exaggerated pancreatic polypeptide secretion in Pima Indians: Can an increased parasympathetic drive to the pancreas contribute to hyperinsulinemia, obesity, and diabetes in humans?
    • Weyer C, Salbe AD, Lindsay RS (2001) Exaggerated pancreatic polypeptide secretion in Pima Indians: can an increased parasympathetic drive to the pancreas contribute to hyperinsulinemia, obesity, and diabetes in humans? Metabolism 50:223-230
    • (2001) Metabolism , vol.50 , pp. 223-230
    • Weyer, C.1    Salbe, A.D.2    Lindsay, R.S.3
  • 19
    • 34648832021 scopus 로고    scopus 로고
    • Plasma pancreatic polypeptide levels are associated with differences in body fat distribution in human subjects
    • Tong J, Utzschneider KM, Carr DB (2007) Plasma pancreatic polypeptide levels are associated with differences in body fat distribution in human subjects. Diabetologia 50:439-442
    • (2007) Diabetologia , vol.50 , pp. 439-442
    • Tong, J.1    Utzschneider, K.M.2    Carr, D.B.3
  • 21
    • 0030936890 scopus 로고    scopus 로고
    • Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycaemia in women
    • Havel PJ, Ahrén B (1997) Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycaemia in women. Diabetes 46:801-807
    • (1997) Diabetes , vol.46 , pp. 801-807
    • Havel, P.J.1    Ahrén, B.2
  • 22
    • 0035029806 scopus 로고    scopus 로고
    • The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia
    • Ahrén B, Holst JJ (2001) The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. Diabetes 50:1030-1038
    • (2001) Diabetes , vol.50 , pp. 1030-1038
    • Ahrén, B.1    Holst, J.J.2
  • 23
    • 0021751981 scopus 로고
    • Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
    • Ward WK, Bolgiano DC, McKnight B (1984) Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 74:1318-1328
    • (1984) J Clin Invest , vol.74 , pp. 1318-1328
    • Ward, W.K.1    Bolgiano, D.C.2    McKnight, B.3
  • 24
    • 0031863755 scopus 로고    scopus 로고
    • Glucose-dependent arginine stimulation test for characterization of islet function: Studies on reproducibility and priming effect of arginine
    • Larsson H, Ahrén B (1998) Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine. Diabetologia 41:1772-1777
    • (1998) Diabetologia , vol.41 , pp. 1772-1777
    • Larsson, H.1    Ahrén, B.2
  • 25
    • 0021522787 scopus 로고
    • Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men
    • Beard JC, Halter JB, Best JD et al (1984) Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men. Am J Physiol 247:E592-E596
    • (1984) Am J Physiol , vol.247
    • Beard, J.C.1    Halter, J.B.2    Best, J.D.3
  • 26
    • 0023926066 scopus 로고
    • The parasympathetic nervous system and glucocorticoid-mediated hyperinsulinaemia in the genetically obese/fa/fa) obese rodents
    • Fletcher JM, McKenzie N (1988) The parasympathetic nervous system and glucocorticoid-mediated hyperinsulinaemia in the genetically obese/fa/fa) obese rodents. J Endocrinol 118:87-92
    • (1988) J Endocrinol , vol.118 , pp. 87-92
    • Fletcher, J.M.1    McKenzie, N.2
  • 27
    • 0030831040 scopus 로고
    • Chronic central neuropeptide Y infusion in normal rats: Status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia
    • Sainsbury A, Rohner-Jeanrenaud F, Cusin I (1977) Chronic central neuropeptide Y infusion in normal rats: status of the hypothalamo-pituitary- adrenal axis, and vagal mediation of hyperinsulinaemia. Diabetologia 40:1269-1277
    • (1977) Diabetologia , vol.40 , pp. 1269-1277
    • Sainsbury, A.1    Rohner-Jeanrenaud, F.2    Cusin, I.3
  • 28
    • 0018959206 scopus 로고
    • Effect of dexamethasone and cortisone on insulin receptors in normal human male
    • DePirro R, Bertolli A, Fusco A (1980) Effect of dexamethasone and cortisone on insulin receptors in normal human male. J Clin Endocrinol Metab 51:503-507
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 503-507
    • Depirro, R.1    Bertolli, A.2    Fusco, A.3
  • 30
    • 0027398256 scopus 로고
    • Effect of dexamethasone on insulin sensitivity, islet amyloid polypeptide and insulin secretion in humans
    • Ludvik B, Clodi M, Kautzki-Willer A et al (1993) Effect of dexamethasone on insulin sensitivity, islet amyloid polypeptide and insulin secretion in humans. Diabetologia 36:84-87
    • (1993) Diabetologia , vol.36 , pp. 84-87
    • Ludvik, B.1    Clodi, M.2    Kautzki-Willer, A.3
  • 31
    • 0034078505 scopus 로고    scopus 로고
    • Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance
    • Larsson H, Ahrén B (2000) Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance. Diabetes Care 23:650-657
    • (2000) Diabetes Care , vol.23 , pp. 650-657
    • Larsson, H.1    Ahrén, B.2
  • 32
    • 0036314331 scopus 로고    scopus 로고
    • Quantification of insulin secretion in relation to insulin sensitivity in non-diabetic post-menopausal women
    • Suppl 1
    • Ahrén B, Larsson H (2002) Quantification of insulin secretion in relation to insulin sensitivity in non-diabetic post-menopausal women. Diabetes 52(Suppl 1):S202-S211
    • (2002) Diabetes , vol.52
    • Ahrén, B.1    Larsson, H.2
  • 33
    • 0030866606 scopus 로고    scopus 로고
    • Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets
    • Lambillotte C, Gilon P, Henquin JC (1997) Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets. J Clin Invest 99:414-423
    • (1997) J Clin Invest , vol.99 , pp. 414-423
    • Lambillotte, C.1    Gilon, P.2    Henquin, J.C.3
  • 34
    • 0031839468 scopus 로고    scopus 로고
    • Increased glucocorticoid sensitivity in islet beta-cells: Effects on glucose-6-phosphatase, glucose cycling and insulin release
    • Ling ZC, Khan A, Delauyny F et al (1998) Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose-6-phosphatase, glucose cycling and insulin release. Diabetologia 41:634-639
    • (1998) Diabetologia , vol.41 , pp. 634-639
    • Ling, Z.C.1    Khan, A.2    Delauyny, F.3
  • 35
    • 1442276959 scopus 로고    scopus 로고
    • Parasympathetic blockade attenuates augmented pancreatic polypeptide but not insulin secretion in Pima Indians
    • Vozarova de Courten B, Weyer C et al (2004) Parasympathetic blockade attenuates augmented pancreatic polypeptide but not insulin secretion in Pima Indians. Diabetes 53:663-671
    • (2004) Diabetes , vol.53 , pp. 663-671
    • Vozarova De Courten, B.1    Weyer, C.2
  • 36
    • 0036839976 scopus 로고    scopus 로고
    • Selective parasympathetic innervation of subcutaneous and intraabdominal fat-functional implications
    • Kreier F, Fliers E, Voshol PJ et al (2002) Selective parasympathetic innervation of subcutaneous and intraabdominal fat-functional implications. J Clin Invest 110:1243-1250
    • (2002) J Clin Invest , vol.110 , pp. 1243-1250
    • Kreier, F.1    Fliers, E.2    Voshol, P.J.3
  • 37
    • 0023912682 scopus 로고
    • Body fat and the activity of the autonomic nervous system
    • Peterson HR, Rotschild M, Weinberg CR et al (1988) Body fat and the activity of the autonomic nervous system. N Engl J Med 318:1077-1083
    • (1988) N Engl J Med , vol.318 , pp. 1077-1083
    • Peterson, H.R.1    Rotschild, M.2    Weinberg, C.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.