Angiotensinogen gene polymorphism predicts hypertension, and iridological constitutional classification enhances the risk for hypertension in Koreans

International Journal of Neuroscience

Volumn 118, Issue 5, 2008, Pages 635-645

  Cho, Joo Jang ^a   Hwang, Woo Jun ^a   Hong, Seung Heon ^b   Jeong, Hyun Ja ^c   Lee, Hye Jung ^d   Kim, Hyung Min ^d   Um, Jae Young ^d  

^a Wonkwang University   (South Korea)

^b Wonkwang University   (South Korea)

^c Biochys Research Center   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

Angiotensinogen; Gene; Hypertension; Iris constitution

Indexed keywords

ANGIOTENSINOGEN;

ADULT; ALLELE; ALTERNATIVE MEDICINE; ANGIOTENSIN CONVERTING ENZYME GENE; ANGIOTENSINOGEN GENE; ARTICLE; BRAIN INFARCTION; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DISEASE CLASSIFICATION; DNA POLYMORPHISM; EYE COLOR; FAMILY HISTORY; GENE; GENE FREQUENCY; GENETIC MARKER; GENOTYPE; HEREDITY; HUMAN; HYPERTENSION; IRIDOLOGY; IRIS; MAJOR CLINICAL STUDY; PIGMENTATION; PREDICTION; RISK ASSESSMENT; RISK FACTOR;

ADULT; ANGIOTENSINOGEN; CHI-SQUARE DISTRIBUTION; CONNECTIVE TISSUE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERTENSION; IRIS; KOREA; MALE; MEDICINE, ORIENTAL TRADITIONAL; MIDDLE AGED; PIGMENTATION; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT;

EID: 43049130057     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.1080/00207450701242628     Document Type: Article

References (25)

1. Agachan, B., Isbir, T., Yilmaz, H., & Akoglu, E. (2003). Angiotensin converting enzyme I/D, angiotensinogen T174M-M235T and angiotensin II type 1 receptor A1166C gene polymorphisms in Turkish hypertensive patients. Experimental Molecular Medicine, 35, 545-549.
2. Barley, J., Markus, H., Brown, M., & Carter, N. (1995). Lack of association between angiotensinogen polymorphism (M235T) and cerebrovascular disease and carotid atheroma. Journal of Human Hypertension, 9, 681-683.
3. Borecki, I. B., Province, M. A., Ludwig, E. H., Ellison, R. C., Folsom, A. R., Heiss, G., Lalouel, J. M., Higgins, M., & Rao, D. C. (1997). Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI Family Heart Study. Annals of Epidemiology, 7, 13-21.
4. Caulfield, M., Lavender, P., Farrall, M., Munroe, P., Lawson, M., Turner, P., & Clark, A. J. (1994). Linkage of the angiotensinogen gene to essential hypertension. New England Journal of Medicine, 330, 1629-1633.
5. Caulfield, M., Lavender, P., Newell-Price, J., Kamdar, S., Farrall, M., & Clark, A. J. (1996). Angiotensinogen in human essential hypertension. Hypertension, 28, 1123-1125.
6. Costerousse, O., Allegrini, J., Lopez, M., & Alhenc-Gelas, F. (1993). Angiotensin I-converting enzyme in human circulating mononuclear cells: Genetic polymorphism of expression in T-lymphocytes. Biochemical Journal, 290, 33-40.
7. Danser, A. H., Schalekamp, M. A., Bax, W. A., Van Den Brink, A. M., Saxena, P. R., Riegger, G. A., & Schunkert, H. (1995). Angiotensin- converting enzyme in human heart. Effect of the deletion/insertion polymorphism. Circulation, 92, 1387-1388.
8. Dzau, V., & Pratt, R. (1991). The heart and cardiovascular system. In H. A. Fozzard, H. E. Harber, R. B. Jennings, A. M. Katz, & H. E. Morgan (Eds.), Renin-angiotensin system. (pp. 1817-1850). New York: Raven Press.
9. Fernandez-Arcas, N., Dieguez-Lucena, J. L., Munoz-Moran, E., Ruiz-Galdon, M., Espinosa-Caliani, S., Aranda-Lara, P., Rius-Diaz, F., Gaitan-Arroyo, M. J., De Teresa-Galvan, E., & Reyes-Engel, A. (2001). Both alleles of the M235T polymorphism of the angiotensinogen gene can be a risk factor for myocardial infarction. Clinical Genetics, 60, 52-57.
10. Goldenberg, I., Moss, A. J., Ryan, D., McNitt, S., Eberly, S. W., & Zareba, W. (2006). Polymorphism in the angiotensinogen gene, hypertension, and ethnic differences in the risk of recurrent coronary events. Hypertension, 48, 693-639.
11. Hooper, W. C., Dowling, N. F., Wenger, N. K., Dilley, A., Ellingsen, D., & Evatt, B. L. (2002). Relationship of venous thromboembolism and myocardial infarction with the renin-angiotensin system in African-Americans. American Journal of Hematology, 70, 1-8.
12. Jeunemaitre, X., Charru, A., Chatellier, G., Dumont, C., Sassano, P., Soubrier, F., Menard, J., & Corvol, P. (1993). M235T variant of the human angiotensinogen gene in unselected hypertensive patients. Journal of Hypertension, 11, S80-S81.
13. Jeunemaitre, X., Inoue, I., Williams, C., Charru, A., Tichet, J., Powers, M., Sharma, A. M., Gimenez-Roqueplo, A. P., Hata, A., Corvol, P., & Lalouel, J. M. (1997). Haplotypes of angiotensinogen in essential hypertension. American Journal of Human Genetics, 60, 1448-1460.
14. Jeunemaitre, X., Soubrier, F., Kotelevtsev, Y. V., Lifton, R. P., Williams, C. S., Charru, A., Hunt, S. C., Hopkins, P. N., Williams, R. R., & Lalouel, J. M. (1992). Molecular basis of human hypertension: role of angiotensinogen. Cell, 71, 169-180.
15. Kamitani, A., Rakugi, H., Higaki, J., Yi, Z., Mikami, H., Miki, T., & Ogihara, T. (1994). Association analysis of a polymorphism of the angiotensinogen genewith essential hypertension in Japanese. Journal of Human Hypertension, 8, 521-524.
16. Katsuya, T., Koike, G., Yee, T. W., Sharpe, N., Jackson, R., Norton, R., Horiuchi, M., Pratt, R. E., Dzau, V. J., & MacMahon, S. (1995). Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. Lancet, 345, 1600-1603.
17. Kiema, T. R., Kauma, H., Rantala, A. O., Lilja, M., Reunanen, A., Kesaniemi, Y. A., & Savolainen, M. J. (1996). Variation at the angiotensin-converting enzyme gene and angiotensinogen gene loci in relation to blood pressure. Hypertension, 28, 1070-1075.
18. Kim, H. S., Krege, J. H., Kluckman, K. D., Hagaman, J. R., Hodgin, J. B., Best, C. F., Jennette, J. C., Coffman, T. M., Maeda, N., & Smithies, O. (1995). Genetic control of blood pressure and the angiotensinogen locus. Proceedings of the National Academy Sciences of the United States of America, 92, 2735-2739.
19. Nakata, Y., Katsuya, T., Rakugi, H., Takami, S., Sato, N., Kamide, K., Ohishi, M., Miki, T., Higaki, J., & Ogihara, T. (1997). Polymorphism of angiotensin converting enzyme, angiotensinogen, and apolipoprotein E genes in a Japanese population with cerebrovascular disease. American Journal of Hypertension, 10, 1391-1395.
20. Russ, A. P., Maerz, W., Ruzicka, V., Stein, U., & Gross, W. (1993). Rapid detection of the hypertension-associated Met235 - >Thr allele of the human angiotensinogen gene. Human Molecular Genetics, 2, 609-610.
21. Sharan, F. (1989). Iridology: A complete guide to diagnosing through the iris and to related forms of treatment. Wellingborough, England: Thorsons Publications Ltd.
22. Solari, V., & Puri, P. (2004). Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension. Journal of Pediatric Surgery, 39, 302-306.
23. Staessen, J. A., Kuznetsova, T., Wang, J. G., Emelianov, D., Vlietinck, R., & Fagard, R. (1999). M235T angiotensinogen gene polymorphism and cardiovascular renal risk. Journal of Hypertension, 17, 9-17.
24. Thomas, G. N., Young, R. P., Tomlinson, B., Woo, K. S., Sanderson, J. E., & Critchley, J. A. (2000). Renin-angiotensin-aldosterone system gene polymorphisms and hypertension in Hong Kong Chinese. Clinical and Experimental Hypertension, 22, 87-97.
25. Um, J. Y., An, N. H., Yang, G. B., Lee, G. M., Cho, J. J., Cho, J. W., Hwang, W. J., Chae, H. J., Kim, H. R., Hong, S. H., & Kim, H. M. (2005). Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism. American Journal of Chinese Medicine, 33, 501-505.