Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL

Biochemical Pharmacology

Volumn 75, Issue 11, 2008, Pages 2175-2182

  Park, Cheol Kyu ^a   Lee, Youngkyun ^a   Chang, Eun Ju ^a   Lee, Ming Hong ^b   Yoon, Jeong Hoon ^b   Ryu, Jae Ha ^b   Kim, Hong Hee ^a  

^a Seoul National University   (South Korea)

^b Sookmyung Women's University   (South Korea)

Author keywords

Bavachalcone; c Fos; NFATc1; Osteoclast differentiation; RANKL

Indexed keywords

BAVACHALCONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN KINASE B; PSORALEA CORYLIFOLIA EXTRACT; TRANSCRIPTION FACTOR NFAT;

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CELL ACTIVITY; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG ISOLATION; DRUG MECHANISM; IC 50; IN VITRO STUDY; MEDICINAL PLANT; MOUSE; NEWBORN; NONHUMAN; ONCOGENE C FOS; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PSORALEA; PSORALEA CORYLIFOLIA; STEM CELL;

ANIMALS; BONE RESORPTION; CELL DIFFERENTIATION; CHALCONES; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONES; GENE EXPRESSION REGULATION; GENES, FOS; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; OSTEOGENESIS; PROTO-ONCOGENE PROTEINS C-AKT; PSORALEA; RANK LIGAND;

EID: 43049128125     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.03.007     Document Type: Article

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