Severe course of rat bite-associated Weil's disease in a patient diagnosed with a new Leptospira-specific real-time quantitative LUX-PCR

Journal of Medical Microbiology

Volumn 57, Issue 5, 2008, Pages 658-663

  Roczek, Alexandra ^a   Forster, Christian ^b   Raschel, Heribert ^a   Hörmansdorfer, Stefan ^a   Bogner, Karl Heinz ^a   Hafner Marx, Angela ^a   Lepper, Hans ^a   Dobler, Gerhard ^c   Büttner, Mathias ^a   Sing, Andreas ^a  

^a BAVARIAN HEALTH AND FOOD SAFETY AUTHORITY   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c Inst of Microbiol of the Bw   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENEM; PENICILLIN G;

ADULT; ARTICLE; BITE; CASE REPORT; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DISEASE COURSE; FEMALE; HUMAN; LEPTOSPIRA; LEPTOSPIROSIS; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; ANIMALS; ANTIBODIES, BACTERIAL; BITES AND STINGS; DIAGNOSIS, DIFFERENTIAL; DNA, BACTERIAL; FEMALE; HUMANS; LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE; POLYMERASE CHAIN REACTION; RATS; WEIL DISEASE; ZOONOSES;

EID: 43049120336     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.47677-0     Document Type: Article

References (17)

1. Baranton, G. & Postic, D. (2006). Trends in leptospirosis epidemiology in France. Sixty-six years of passive serological surveillance from 1920 to 2003. Int J Infect Dis 10, 162-170.
2. Bharti, A. R., Nally, J. E., Ricaldi, J. N., Matthias, M. A., Diaz, M. M., Lovett, M. A., Levett, P. N., Gilman, R. H., Willig, M. R. & other authors (2003). Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis 3, 757-771.
3. Brem, S., Staak, C., Schönberg, A., Kopp, H. & Meyer, P. (1999). Beitrag zur Leptospirenserologie des Hundes: Vergleich von MAR-und ELISA-Ergebnissen. Tierarztl Umsch 54, 83-87.
4. Cerny, A., Ettlin, D., Betschen, K., Berchtold, E., Hottinger, S. & Neftel, K. A. (1992). Weil's disease after a rat bite. Eur J Med 1, 315-316.
5. Elliott, S. P. (2007). Rat bite fever and Streptobacillus moniliformis. Clin Microbiol Rev 20, 13-22.
6. Gollop, J. H., Katz, A. R., Rudoy, R. C. & Sasaki, D. M. (1993). Rat-bite leptospirosis. West J Med 159, 76-77.
7. Hanson, L. E. (1982). Leptospirosis in domestic animals: the public health perspective. J Am Vet Med Assoc 181, 1505-1509.
8. Hoik, K., Nielsen, S. V. & Renne, T. (2000). Human leptospirosis in Denmark 1970-1996: an epidemiological and clinical study. Scand J Infect Dis 32, 533-538.
9. Jansen, A., Schöneberg, I., Frank, C., Alpers, K., Schneider, T. & Stark, K. (2005). Leptospirosis in Germany, 1962-2003. Emerg Infect Dis 11, 1048-1054.
10. Jauréguiberry, S., Roussel, M., Brinchault-Rabin, G., Gacouin, A., Le Meur, A., Arvieux, C., Michelet, C. & Tattevin, P. (2005). Clinical presentation of leptospirosis: a retrospective study of 34 patients admitted to a single institution in metropolitan France. Clin Microbiol Infect 11, 391-394.
11. Levett, P. N., Morey, R. E., Galloway, R. L., Turner, D. E., Steigerwalt, A. G. & Mayer, L. W. (2005). Detection of pathogenic leptospires by real-time quantitative PCR. J Med Microbiol 54, 45-49.
12. Luzzi, G. A., Milne, L. M. & Waitkins, S. A. (1987). Rat-bite acquired leptospirosis. J Infect 15, 57-60.
13. Panaphut, T., Domrongkitchaiporn, S., Vibhagool, A., Thinkamrop, B. & Susaengrat, W. (2003). Ceftriaxone compared with sodium penicillin G for treatment of severe leptospirosis. Clin Infect Dis 36, 1507-1513.
14. Segura, E. R., Ganoza, C. A., Campos, K., Ricaldi, J. N., Torres, S., Silva, H., Céspedes, M. J., Matthias, M. A., Swancutt, M. A. & other authors (2005). Clinical spectrum of pulmonary involvement in leptospirosis in a region of endemicity, with quantification of leptospiral burden. Clin Infect Dis 40, 343-351.
15. Smythe, L. D., Smith, I. L., Smith, G. A., Dohnt, M. F., Symonds, M. L., Barnett, L. J. & McKay, D. B. (2002). A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp. BMC Infect Dis 2, 13.
16. Viriyakosol, S., Matthias, M. A., Swancutt, M. A., Kirkland, T. N. & Vinetz, J. M. (2006). Toll-like receptor 4 protects against lethal Leptospira interrogans serovar Icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden. Infect Immun 74, 887-895.
17. WHO & ILS (2003). Human Leptospirosis: Guidance for Diagnosis, Surveillance and Control. Geneva: World Health Organization & International Leptospirosis Society.