Mild hepatitis at recommended doses of acetaminophen in patients with evidence of constitutionally enhanced cytochrome P450 system activity

Journal of Clinical Pharmacy and Therapeutics

Volumn 33, Issue 3, 2008, Pages 315-320

  Grieco, A ^a,b   Miele, L ^a   Forgione, A ^a   Ragazzoni, E ^a   Vecchio, F M ^a   Gasbarrini, G ^a  

^a FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Acetaminophen; Adverse drug reaction; Antipyrine; Cytochrome P450; Danger hypothesis; Drug induced liver disease; Idiosyncratic drug reaction; Liver toxicity; Paracetamol

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450; GAMMA GLUTAMYLTRANSFERASE; NON PRESCRIPTION DRUG; PARACETAMOL;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ALKALINE PHOSPHATASE BLOOD LEVEL; ANALYTIC METHOD; ANTIPYRENE TEST; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE REPORT; DIET RESTRICTION; DISEASE SEVERITY; DRUG WITHDRAWAL; ENZYME ACTIVITY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEPATITIS; HUMAN; HUMAN TISSUE; LIVER INJURY; LIVER TOXICITY; MALE; MALNUTRITION; OXIDATION; PRESCRIPTION; SIDE EFFECT;

ACETAMINOPHEN; ADULT; ANALGESICS, NON-NARCOTIC; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HEPATITIS, CHRONIC, DRUG-INDUCED; HUMANS; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES;

EID: 43049106836     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2008.00918.x     Document Type: Article

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