Adaptive changes in the expression of central opioid receptors in mice lacking the dopamine D2 receptor gene

Neuroscience

Volumn 153, Issue 3, 2008, Pages 773-788

  Lena I ^a   Bradshaw, S ^b   Pintar, J ^b   Kitchen, I ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

autoradiography; basal ganglia; dopaminergic system; knockout mice; opioidergic system

Indexed keywords

DELTA OPIATE RECEPTOR; DOPAMINE 2 RECEPTOR; DYNORPHIN; ENKEPHALIN; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NOCICEPTIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BASAL GANGLION; BRAIN; CONTROLLED STUDY; CORPUS STRIATUM; GENE DELETION; GENOTYPE; GLOBUS PALLIDUS; HETEROZYGOTE; HOMOZYGOTE; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SPINAL CORD;

EID: 43049096365     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.02.070     Document Type: Article

References (67)

1. O. Aizman H. Brismar P. Uhlen E. Zettergren A.I. Levey H. Forssberg P. Greengard A. Aperia Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons Nat Neurosci 3 2000 226 230
2. L.M. Ambrose E.M. Unterwald E.J. Van Bockstaele Ultrastructural evidence for co-localization of dopamine D2 and mu-opioid receptors in the rat dorsolateral striatum Anat Rec A Discov Mol Cell Evol Biol 279 2004 583 591
3. J.A. Angulo B.S. McEwen Molecular aspects of neuropeptide regulation and function in the corpus striatum and nucleus accumbens Brain Res Rev 19 1994 1 28
4. J.H. Baik R. Picetti A. Saiardi G. Thiriet A. Dierich A. Depaulis M. Le Meur E. Borrelli Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors Nature 377 1995 424 428
5. A. Bailey C. Ledent M. Kelly S.M. Hourani I. Kitchen Changes in spinal delta and kappa opioid systems in mice deficient in the A2A receptor gene J Neurosci 22 2002 9210 9220
6. A. Boom C. Mollereau J.C. Meunier G. Vassart M. Parmentier J.J. Vanderhaeghen S.N. Schiffmann Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system Neuroscience 91 1999 991 1007
7. M.L. Bouthenet M.P. Martres N. Sales J.C. Schwartz A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride Neuroscience 20 1987 117 155
8. J.J. Bouyer R.J. Miller V.M. Pickel Ultrastructural relation between cortical efferents and terminals containing enkephalin-like immunoreactivity in rat neostriatum Regul Pept 8 1984 105 115
9. C.M. Bower T.M. Hyde M. Zaka E.H. Hamid S.M. Baca M.F. Egan Decreased mu-opioid receptor binding in the globus pallidus of rats treated with chronic haloperidol Psychopharmacology (Berl) 150 2000 260 263
10. V.I. Chefer T.S. Shippenberg Paradoxical effects of prodynorphin gene deletion on basal and cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens Eur J Neurosci 23 2006 229 238
11. J.F. Chen V.J. Aloyo Z.H. Qin B. Weiss Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases D2 dopamine receptor mRNA and proenkephalin mRNA and decreases D1 dopamine receptor mRNA and mu and delta opioid receptors in rat striatum Neurochem Int 25 1994 355 366
12. S. Clarke A. Zimmer A.M. Zimmer R.G. Hill I. Kitchen Region selective up-regulation of mu-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice Neuroscience 122 2003 479 489
13. S. Dasgupta S. Ferré B. Kull P.B. Hedlund U.B. Finnman S. Ahlberg E. Arenas B.B. Fredholm K. Fuxe Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells Eur J Pharmacol 316 1996 325 331
14. V. Daugé P.W. Kalivas T. Duffy B.P. Roques Effect of inhibiting enkephalin catabolism in the VTA on motor activity and extracellular dopamine Brain Res 599 1992 209 214
15. J.B. Daunais J.F. McGinty The effects of D1 or D2 dopamine receptor blockade on zif/268 and preprodynorphin gene expression in rat forebrain following a short-term cocaine binge Brain Res Mol 35 1996 237 248
16. J.M. Delfs L. Yu G.D. Ellison T. Reisine M.F. Chesselet Regulation of mu-opioid receptor mRNA in rat globus pallidus: effects of enkephalin increases induced by short- and long-term haloperidol administration J Neurochem 63 1994 777 780
17. G. Di Chiara A. Imperato Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rat J Pharmacol Exp Ther 244 1988 1067 1080
18. S.D. Dickinson J. Sabeti G.A. Larson K. Giardina M. Rubinstein M.A. Kelly D.K. Grandy M.J. Low G.A. Gerhardt N.R. Zahniser Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum J Neurochem 72 1999 148 156
19. A. Di Giannuario S. Pieretti A. Catalani A. Loizzo Orphanin FQ reduces morphine-induced dopamine release in the nucleus accumbens: a microdialysis study in rats Neurosci Lett 272 1999 183 186
20. C.L. Dockstader M. Rubinstein D.K. Grandy M.J. Low D. van der Kooy The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice Eur J Neurosci 13 2001 995 1001
21. G.I. Elmer J.O. Pieper M. Rubinstein M.J. Low D.K. Grandy R.A. Wise Failure of intravenous morphine to serve as an effective instrumental reinforcer in dopamine D2 receptor knock-out mice J Neurosci 22 2002 RC224
22. C.A. Fox A. Mansour S.J. Watson The effects of haloperidol on dopamine receptor gene expression Exp Neurol 130 1994 288 303
23. M. Funada T. Suzuki M. Narita M. Misawa H. Nagase Blockade of morphine reward through the activation of kappa-opioid receptors in mice Neuropharmacology 32 1993 1315 1323
24. C.R. Gerfen T.M. Engber L.C. Mahan Z. Susel T.N. Chase F.J. Monsma Jr D.R. Sibley D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons Science 250 1990 1429 1432
25. C.R. Gerfen The neostriatal mosaic: multiple levels of compartmental organization Trends Neurosci 15 1992 133 139
26. C. Gouarderes J. Cros R. Quirion Autoradiographic localization of mu, delta and kappa opioid receptor binding sites in rat and guinea pig spinal cord Neuropeptides 6 1985 331 342
27. M.D. Hayward M.J. Low Naloxone's suppression of spontaneous and food-conditioned locomotor activity is diminished in mice lacking either the dopamine D(2) receptor or enkephalin Brain Res Mol 140 2005 91 98
28. H.K. Jiang J.F. McGinty J. Hong Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes Brain Res 507 1990 57 64
29. M.O. Job V. Ramachandra S. Anders M.J. Low R.A. Gonzales Reduced basal and ethanol stimulation of striatal extracellular dopamine concentrations in dopamine D2 receptor knockout mice Synapse 60 2006 158 164
30. M.Y. Jung B.V. Skryabin M. Arai S. Abbondanzo D. Fu J. Brosius N.K. Robakis H.G. Polites J.E. Pintar C. Schmauss Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors Neuroscience 91 1999 911 924
31. P.W. Kalivas E. Widerlov D. Stanley G. Breese A.J. Prange Jr Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity J Pharmacol Exp Ther 227 1983 229 237
32. M.A. Kelly M. Rubinstein T.J. Phillips C.N. Lessov S. Burkhart-Kasch G. Zhang J.R. Bunzow Y. Fang G.A. Gerhardt D.K. Grandy M.J. Low Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations J Neurosci 18 1998 3470 3479
33. M.A. King S. Bradshaw A.H. Chang J.E. Pintar G.W. Pasternak Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system J Neurosci 21 2001 7788 7792
34. I. Kitchen S.J. Slowe H.W. Matthes B.L. Kieffer Quantitative autoradiographic mapping of mu-, delta- and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene Brain Res 778 1997 73 88
35. M. Koizumi N. Midorikawa H. Takeshima N.P. Murphy Exogenous, but not endogenous nociceptin modulates mesolimbic dopamine release in mice J Neurochem 89 2004 257 263
36. S.R. Laviolette R.A. Gallegos S.J. Henriksen D. van der Kooy Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area Nat Neurosci 7 2004 160 169
37. C. Le Moine B. Bloch D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum J Comp Neurol 355 1995 418 426
38. I. Léna H. Matthes B. Kieffer I. Kitchen Quantitative autoradiography of dopamine receptors in the brains of mu-opioid receptor knockout mice Neurosci Lett 356 2004 220 224
39. B. Levant K.E. McCarson D(3) dopamine receptors in rat spinal cord: implications for sensory and motor function Neurosci Lett 303 2001 9 12
40. D. Levesque J. Diaz C. Pilon M.P. Martres B. Giros E. Souil D. Schott J.L. Morgat J.C. Schwartz P. Sokoloff Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin Proc Natl Acad Sci U S A 89 1992 8155 8159
41. K. Lutfy T. Do N.T. Maidment Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats Psychopharmacology (Berl) 154 2001 1 7
42. R. Maldonado A. Saiardi O. Valverde T.A. Samad B.P. Roques E. Borrelli Absence of opiate rewarding effects in mice lacking dopamine D2 receptors Nature 388 1997 586 589
43. C. Manzanedo M.A. Aguilar M. Rodriguez-Arias J. Minarro Effects of dopamine antagonists with different receptor blockade profiles on morphine-induced place preference in male mice Behav Brain Res 121 2001 189 197
44. M. Mavridis M.J. Besson Dopamine-opiate interaction in the regulation of neostriatal and pallidal neuronal activity as assessed by opioid precursor peptides and glutamate decarboxylase messenger RNA expression Neuroscience 92 1999 945 966
45. J.C. Meunier C. Mollereau L. Toll C. Suaudeau C. Moisand P. Alvinerie J.L. Butour J.C. Guillemot P. Ferrara B. Monsarrat Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor Nature 377 1995 532 535
46. T. Mori M. Nomura H. Nagase M. Narita T. Suzuki Effects of a newly synthesized kappa-opioid receptor agonist, TRK-820, on the discriminative stimulus and rewarding effects of cocaine in rats Psychopharmacology (Berl) 161 2002 17 22
47. B.J. Morris V. Höllt A. Herz Dopaminergic regulation of striatal proenkephalin mRNA and prodynorphin mRNA: contrasting effects of D1 and D2 antagonists Neuroscience 25 1988 525 532
48. M.G. Murer G. Dziewczapolski P. Salin M. Vila K.Y. Tseng M. Ruberg M. Rubinstein M.A. Kelly D.K. Grandy M.J. Low E. Hirsch R. Raisman-Vozari O. Gershanik The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice Neuroscience 99 2000 643 650
49. N.P. Murphy H.T. Ly N.T. Maidment Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats Neuroscience 75 1996 1 4
50. S. Narayanan H. Lam L. Christian M.S. Levine D. Grandy M. Rubinstein N.T. Maidment Endogenous opioids mediate basal hedonic tone independent of dopamine D-1 or D-2 receptor activation Neuroscience 124 2004 241 246
51. R.K. Reinscheid H.P. Nothacker A. Bourson A. Ardati R.A. Henningsen J.R. Bunzow D.K. Grandy H. Langen F.J. Monsma Jr Civelli Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor Science 270 1995 792 794
52. F. Rouge-Pont A. Usiello M. Benoit-Marand F. Gonon P.V. Piazza E. Borrelli Changes in extracellular dopamine induced by morphine and cocaine: crucial control by D2 receptors J Neurosci 22 2002 3293 3301
53. K. Sakoori N.P. Murphy Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice Psychopharmacology (Berl) 172 2004 129 136
54. T. Sasaki J.L. Kennedy J.N. Nobrega Autoradiographic mapping of mu opioid receptor changes in rat brain after long-term haloperidol treatment: relationship to the development of vacuous chewing movements Psychopharmacology (Berl) 128 1996 97 104
55. S.P. Sivam Dopaminergic regulation of striatonigral tachykinin and dynorphin gene expression: a study with the dopamine uptake inhibitor GBR-12909 Brain Res Mol 35 1996 197 210
56. S.J. Slowe S. Clarke I. Léna R.J. Goody R. Lattanzi L. Negri F. Simonin H.W. Matthes D. Filliol B.L. Kieffer I. Kitchen Autoradiographic mapping of the opioid receptor-like 1 (ORL1) receptor in the brains of mu-, delta- or kappa-opioid receptor knockout mice Neuroscience 106 2001 469 480
57. R. Spanagel A. Herz T. Shippenberg Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway Proc Natl Acad Sci U S A 89 1992 2046 2050
58. R. Spanagel F. Weiss The dopamine hypothesis of reward: past and current status Trends Neurosci 22 1999 521 527
59. A.L. Svingos A. Moriwaki J.B. Wang G.R. Uhl V.M. Pickel Ultrastructural immunocytochemical localization of mu-opioid receptors in rat nucleus accumbens: extrasynaptic plasmalemmal distribution and association with Leu5-enkephalin J Neurosci 16 1996 4162 4173
60. A.L. Svingos A. Moriwaki J.B. Wang G.R. Uhl V.M. Pickel Mu-opioid receptors are localized to extrasynaptic plasma membranes of GABAergic neurons and their targets in the rat nucleus accumbens J Neurosci 17 1997 2585 2594
61. A.L. Svingos C.L. Clarke V.M. Pickel Cellular sites for activation of delta-opioid receptors in the rat nucleus accumbens shell: relationship with Met5-enkephalin J Neurosci 18 1998 1923 1933
62. A.L. Svingos E.E. Colago V.M. Pickel Cellular sites for dynorphin activation of kappa-opioid receptors in the rat nucleus accumbens shell J Neurosci 19 1999 1804 1813
63. K.A. Trujillo R. Day H. Akil Regulation of striatonigral prodynorphin peptides by dopaminergic agents Brain Res 518 1990 244 256
64. H. Wang A. Moriwaki J.B. Wang G.R. Uhl V.M. Pickel Ultrastructural immunocytochemical localization of mu opioid receptors and Leu5-enkephalin in the patch compartment of the rat caudate-putamen nucleus J Comp Neurol 375 1996 659 674
65. J.Q. Wang J.F. McGinty D1 and D2 receptor regulation of preproenkephalin and preprodynorphin mRNA in rat striatum following acute injection of amphetamine or methamphetamine Synapse 22 1996 114 122
66. C.J. Wilson P.M. Groves Fine structure and synaptic connections of the common spiny neuron of the rat neostriatum: a study employing intracellular inject of horseradish peroxidase J Comp Neurol 194 1980 599 615
67. A. Zapata T.S. Shippenberg Lack of functional D2 receptors prevents the effects of the D3-preferring agonist (+)-PD 128907 on dialysate dopamine levels Neuropharmacology 48 2005 43 50