Effect of platelet-rich plasma on the healing of intrabony defects treated with beta tricalcium phosphate and expanded polytetrafluoroethylene membranes

Journal of Periodontology

Volumn 79, Issue 4, 2008, Pages 660-669

  Döri, Ferenc ^a   Huszár, Tamás ^a   Nikolidakis, Dimitris ^b   Tihanyi, Dora ^a   Horváth, Attila ^a   Arweiler, Nicole B ^c   Gera, István ^a   Sculean, Anton ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Beta tricalcium phosphate; Defects; Platelet rich plasma; Polytetrafluoroethylene; Randomized controlled clinical trials; Therapy

Indexed keywords

BETA-TRICALCIUM PHOSPHATE; BIOMATERIAL; CALCIUM PHOSPHATE; POLITEF;

ADULT; ARTICLE; ARTIFICIAL MEMBRANE; BONE PROSTHESIS; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; GINGIVA DISEASE; HUMAN; JAW; MALE; METHODOLOGY; MIDDLE AGED; OSTEOLYSIS; PATHOLOGY; PERIODONTAL DISEASE; PERIODONTICS; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE RICH PLASMA; TOOTH CERVIX; TOOTH PLAQUE; TREATMENT OUTCOME; WOUND HEALING;

ADULT; ALVEOLAR BONE LOSS; ALVEOLAR PROCESS; BIOCOMPATIBLE MATERIALS; BONE SUBSTITUTES; CALCIUM PHOSPHATES; DENTAL PLAQUE INDEX; FEMALE; FOLLOW-UP STUDIES; GINGIVAL RECESSION; GUIDED TISSUE REGENERATION, PERIODONTAL; HUMANS; MALE; MEMBRANES, ARTIFICIAL; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PLATELET-RICH PLASMA; POLYTETRAFLUOROETHYLENE; TOOTH CERVIX; TREATMENT OUTCOME; WOUND HEALING;

EID: 42949178929     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.070473     Document Type: Article

References (56)

1. Karring T, Lindhe J, Cortellini P. Regenerative periodontal therapy. In: Lindhe J, Karring T, Lang NP, eds. Clinical Periodontology and Implant Dentistry. Copenhagen: Blackwell Munksgaard; 2003:650-704.
2. Caffesse RG, Quinones CR. Polypeptide growth factors and attachment proteins in periodontal wound healing and regeneration. Periodontol 2000 1993;1:69-79.
3. Giannobile WV, Finkelman RD, Lynch SE. Comparison of canine and non-human primate animal models for periodontal regenerative therapy. Results following a single administration of PDGF/IGF-I. J Periodontol 1994;65:1158-1168.
4. Lynch SE, Williams RC, Polson AM. A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol 1989;16:545-548.
5. Lynch SE, de Castilla GR, Williams RC, et al. The effects of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. J Periodontol 1991;62:458-467.
6. Rutherford RB, Niekrash CE, Kennedy JE, Charette MF. Platelet-derived and insulin-like growth factors stimulate regeneration of periodontal attachment in monkeys. J Periodontal Res 1992;27:285-290.
7. Rutherford RB, Ryan ME, Kennedy JE, Tucker MM, Charrette MF. Platelet-derived growth factor and dexamethasone combined with a collagen matrix induce regeneration of the periodontium in monkeys. J Clin Periodontol 1993;20:537-544.
8. Wang HL, Pappert TD, Castelli WA, Chiego DJ Jr., Shyr Y, Smith BA. The effect of platelet-derived growth factor on the cellular response of the periodontium: An autoradiographic study on dogs. J Periodontol 1994;65: 429-436.
9. Howell TH, Fiorellini JP, Paquette DW, Offenbacher S, Giannobile WV, Lynch SE. A phase I/II clinical trial to evaluate a combination of recombinant human insulin-like growth factor-I in patients with periodontal disease. J Periodontol 1997;68:1186-1193.
10. Nevins M, Giannobile WV, McGuire MK, et al. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: Results of a large multicenter randomized controlled trial. J Periodontol 2005;76: 2205-2215.
11. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma. Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:638-646.
12. Tözüm TF, Demiralp B. Platelet-rich plasma: A promising innovation in dentistry. J Can Dent Assoc 2003;69: 664-664h.
13. Sanchez AR, Sheridan PJ, Kupp LI. Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants 2003;18:93-103.
14. Marx RE. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg 2004;62:489-496.
15. de Obarrio JJ, Araúz-Dutari JI, Chamberlain TM, Croston A. The use of autologous growth factors in periodontal surgical therapy: Platelet gel biotechnology - Case reports. Int J Periodontics Restorative Dent 2000;20:486-497.
16. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. Platelet-rich plasma and bovine porous bone mineral combined with guided tissue regeneration in the treatment of intrabony defects in humans. J Periodontal Res 2002;37:300-306.
17. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. A reentry study on the use of bovine porous bone mineral, GTR, and platelet-rich plasma in the regenerative treatment of intrabony defects in humans. Int J Periodontics Restorative Dent 2005;25:49-59.
18. Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB. Comparison of platelet-rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet-rich plasma and bovine porous bone mineral in the treatment of intrabony defects: A reentry study. J Periodontol 2002;73:198-205.
19. Hanna R, Trejo PM, Weltman RL. Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: A randomized clinical trial. J Periodontol 2004;75:1668-1677.
20. Okuda K, Tai H, Tanabe K, et al. Platelet-rich plasma combined with a porous hydroxyapatite graft for the treatment of intrabony periodontal defects in humans: A comparative controlled clinical study. J Periodontol 2005;76:890-898.
21. Döri F, Huszár T, Nikolidakis D, et al. Effect of platelet-rich plasma on the healing of intrabony defects treated with a natural bone mineral and a collagen membrane. J Clin Periodontol 2007;34:254-261.
22. Döri F, Huszár T, Nikolidakis D, Arweiler NB, Gera I, Sculean A. Effect of platelet-rich plasma on the healing of intrabony defects treated with an anorganic bovine bone mineral and expanded polytetrafluoroethylene membranes. J Periodontol 2007;78:983-990.
23. Christgau M, Moder D, Wagner J, et al. Influence of autologous platelet concentrate on healing in intra-bony defects following guided tissue regeneration therapy: A randomized prospective clinical split-mouth study. J Clin Periodontol 2006;33:908-921.
24. Yassibag-Berkman Z, Tuncer O, Subasioglu T, Kantarci A. Combined use of platelet-rich plasma and bone grafting with or without guided tissue regeneration in the treatment of anterior interproximal defects. J Periodontol 2007;78:801-809.
25. Peters F, Reif D. Functional materials from beta-tricalcium phosphate (in German). Materwiss Werksttech 2004;35: 203-207.
26. Saffar JL, Colombier ML, Detienville R. Bone formation in tricalcium phosphate-filled periodontal intrabony lesions. Histologic observations in humans. J Periodontol 1990;61:209-216.
27. Gatti AM, Zaffe D, Poli GP. Behaviour of tricalcium phosphate and hydroxyapatite granules in sheep bone defects. Biomaterials 1990;11:513-517.
28. Buser D, Hoffmann B, Bernard JP, Lussi A, Mettler D, Schenk RK. Evaluation of filling materials in membrane-protected bone defects. A comparative histomorphometric study in the mandible of miniature pigs. Clin Oral Implants Res 1998;9:137-150.
29. Merten HA, Wiltfang J, Grohmann U, Hoenig JF. Intra-individual comparative animal study of alpha- and beta-tricalcium phosphate degradation. J Craniofac Surg 2001;12:59-68.
30. Wiltfang J, Merten HA, Schlegel KA, et al. Degradation characteristics of alpha and beta tri-calcium-phosphate (TCP) in minipigs. J Biomed Mater Res 2002;63: 115-121.
31. Stahl SS, Froum S. Histologic evaluation of human intraosseous healing responses to the placement of tricalcium phosphate ceramic implants. I. Three to eight months. J Periodontol 1986;57:211-217.
32. Froum S, Stahl SS. Human intraosseous healing response to the placement of tricalcium phosphate ceramic implants. II. 13 to 18 months. J Periodontol 1987;58:103-109.
33. Strub JR, Gaberthüel TW, Firestone AR. Comparison of tricalcium phosphate and frozen allogenic bone implants in man. J Periodontol 1979;50:624-629.
34. Snyder AJ, Levin MP, Cutright DE. Alloplastic implants of tricalcium phosphate ceramic in human periodontal osseous defects. J Periodontol 1984;55: 273-277.
35. Baldock WT, Hutchens LH Jr., McFall WT Jr., Simpson DM. An evaluation of tricalcium phosphate implants in human periodontal defects of two patients. J Periodontol 1985;56:1-7.
36. Gera I, Döri F, Keglevich T, Anton S, Szilágyi E, Windisch P. Experience with the clinical use of beta-tri-calcium phosphate (Cerasorb) as a bone replacement graft material in human periodontal osseous defects (in Hungarian). Fogorv Sz 2002;95:143-147.
37. Döri F, Arweiler NB, Gera I, Sculean A. Treatment of intrabony defects with an enamel matrix protein derivative and two different types of bone substitutes. J Periodontol 2005;76:2236-2243.
38. Polimeni G, Koo KT, Qahash M, Xiropaidis AV, Albandar JM, Wikesjö UME. Prognostic factors for alveolar regeneration: Effect of a space-providing bio-material on guided tissue regeneration. J Clin Periodontol 2004;31:725-729.
39. Polimeni G, Xiropaidis V, Wikesjö UME. Biology and principles of periodontal wound healing/regeneration. Periodontol 2000 2006;41:30-37.
40. Löe H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38:610-616.
41. Tonetti MS, Pini Prato GP, Cortellini P. Effect of cigarette smoking on periodontal health following GTR in infrabony defects. A preliminary retrospective study. J Clin Periodontol 1995;22:229-234.
42. Fleiss J. The Design and Analysis of Clinical Experiments. New York: John Wiley & Sons; 1986:120-148.
43. Appel TR, Potzsch B, Muller J, von Lindern JJ, Berge SJ, Reich RH. Comparison of three different preparations of platelet concentrates for growth factor enrichment. Clin Oral Implants Res 2002;13:522-528.
44. Tsitoura E, Tucker R, Suvan J, Laurell L, Cortellini P, Tonetti M. Baseline radiographic defect angle of the intrabony defect as a prognostic indicator in regenerative periodontal surgery with enamel matrix derivative. J Clin Periodontol 2004;31:643-647.
45. Cortellini P, Carnevale G, Sanz M, Tonetti MS. Treatment of deep intrabony and shallow intrabony defects. A multicenter randomized controlled clinical trial. J Clin Periodontol 1998;25:981-987.
46. Cortellini P, Tonetti MS. Clinical performance of a regenerative strategy for intrabony defects: Scientific evidence and clinical experience. J Periodontol 2005;76: 341-350.
47. Camelo M, Nevins ML, Schenk R, et al. Clinical, radiographic, and histologic evaluation of human periodontal defects treated with Bio-Oss and Bio-Gide. Int J Periodontics Restorative Dent 1998;18:321-331.
48. Mellonig J. Human histologic evaluation of a bovine-derived xenograft in the treatment of periodontal osseous defects. Int J Periodontics Restorative Dent 2000; 20:19-29.
49. Sculean A, Stavropoulos A, Windisch P, Keglevich T, Karring T, Gera I. Healing of human intrabony defects following regenerative periodontal therapy with a bovine-derived xenograft and guided tissue regeneration. Clin Oral Investig 2004;8:70-74.
50. Okuda K, Kawase T, Momose M, et al. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro. J Periodontol 2003;74:849-857.
51. Kawase T, Okuda K, Saito Y, Yoshie H. In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. J Periodontol 2005; 76:760-767.
52. Kassolis JD, Reynolds MA. Evaluation of the adjunctive benefits of platelet-rich plasma in subantral sinus augmentation. J Craniofac Surg 2005;16:280-287.
53. Rosling B, Nyman S, Lindhe J. The effect of systematic plaque control on bone regeneration in infrabony pockets. J Clin Periodontol 1976;3:38-53.
54. Nyman S, Lindhe J, Rosling B. Periodontal surgery in plaque-infected dentitions. J Clin Periodontol 1977;4: 240-249.
55. Westfelt E, Nyman S, Sokransky S, Lindhe J. Significance of frequency of professional tooth cleaning for healing following periodontal surgery. J Clin Periodontol 1983;10:148-156.
56. Gunsolley JC, Elswick RK, Davenport JM. Equivalence and superiority testing in regeneration clinical trials. J Periodontol 1998;69:521-527.