Famotidine versus pantoprazole for preventing bleeding in the upper gastrointestinal tract of critically ill patients receiving mechanical ventilation

American Journal of Critical Care

Volumn 17, Issue 2, 2008, Pages 142-147

  Ojiako, Kizito ^a   Shingala, Hiren ^a   Schorr, Christa ^b,c   Gerber, David R ^b,c  

^a Critical care medicine ^*

^b Department of Anesthesiology   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[(2 PYRIDYL)METHYL]SULFINYL]BENZIMIDAZOLE DERIVATIVE; FAMOTIDINE; HISTAMINE H2 RECEPTOR ANTAGONIST; PANTOPRAZOLE; PROTON PUMP INHIBITOR;

AGED; ARTICLE; ARTIFICIAL VENTILATION; COMPARATIVE STUDY; HUMAN; MIDDLE AGED; PEPTIC ULCER BLEEDING; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; AGED; FAMOTIDINE; HISTAMINE H2 ANTAGONISTS; HUMANS; MIDDLE AGED; PEPTIC ULCER HEMORRHAGE; PROTON PUMP INHIBITORS; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 42949167824     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Cook DJ, Fuller HD, Guyatt GH, et al. Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group. N Engl J Med. 1994;330(6):377-381.
2. Conover WJ. Practical Nonparametric Statistics. 3rd ed. New York, NY: John Wiley & Sons; 1999.
3. Faisy C, Guerot E, Diehl J, Iftimovici E, Fagon J. Clinically significant gastrointestinal bleeding in critically ill patients with and without stress-ulcer prophylaxis. Intensive Care Med. 2003;29(8):1306-1313.
4. Devlin JW, Ben-Menachem T, Ulep SK, Peters MJ, Fogel RP, Zarowitz BJ. Stress ulcer prophylaxis in medical ICU patients: annual utilization in relation to the incidence of endoscopically proven stress ulceration. Ann Pharmacother. 1998; 32(9):869-874.
5. Zandstra DF, Stoutenbeek CP. The virtual absence of stressulceration related bleeding in ICU patients receiving prolonged mechanical ventilation without any prophylaxis: a prospective cohort study. Intensive Care Med. 1994;20(5): 335-340.
6. Ryan P, Dawson J, Teres D, Celoria G, Navab F. Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate. Arch Surg. 1993;128(12):1353-1357.
7. Prod'hom G, Leuenberger P, Koerfer J, et al. Nosocomial pneumonia in mechanically ventilated patients receiving antacid, ranitidine, or sucralfate as prophylaxis for stress ulcer: a randomized controlled trial. Ann Intern Med. 1994; 120(8):653-662.
8. Ben-Menachem T, Fogel R, Patel RV, et al. Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit: a randomized, controlled, single-blind study. Ann Intern Med. 1994;121(8):568-575.
9. Cook D, Guyatt G, Marshall J, et al. A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. N Engl J Med. 1998;338(12): 791-797.
10. Kantorova H, Svoboda P, Scheer P, et al. Stress ulcer prophylaxis in critically ill patients: a randomized controlled trial. Hepatogastroenterology. 2004;51(57):757-761.
11. Driks MR, Craven DE, Celli BR, et al. Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine type 2 blockers: the role of gastric colonization. N Engl J Med. 1987;317(22):1376-1382.
12. Apte N, Karnad D, Medhekar T, Tilve G, Morye S, Bhave G. Gastric colonization and pneumonia in intubated critically ill patients receiving stress ulcer prophylaxis: a randomized, controlled trial. Crit Care Med. 1992;20(5):590-593.
13. Cook DJ. Stress ulcer prophylaxis: gastrointestinal bleeding and nosocomial pneumonia. Hepatogastroenterology. 1995;30(suppl 210):48-52.
14. Martin LF, Booth FV, Karlstadt RG, et al. Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. Crit Care Med. 1993;21(1):19-30.
15. Fabian T, Boucher B, Croce M, et al. Pneumonia and stress ulceration in severely injured patients. Arch Surg. 1993; 128(2):185-191.
16. Simms H. Gastric alkalinization does not increase the risk of pneumonia in critically ill patients. Semin Respir Infect. 1994;9(4):222-227.
17. Merki HS, Wilder-Smith CH. Do continuous infusions of omeprazole and ranitidine retain their effect with prolonged dosing? Gastroenterology. 1994;106(1):60-64.
18. Conrad SA, Gabrielli A, Margolis B, et al. Randomized, double- blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients. Crit Care Med. 2005;33(4):760-765.
19. Morris J, Karlstadt R, Blatcher D, Field B, McDevitt M. Intermittent intravenous pantoprazole rapidly achieves and maintains gastric pH ≥4.0 compared with continuous infusion H2-receptor antagonist in intensive care unit patients [abstract]. Crit Care Med. 2002;29:A147.
20. Watson TD, Stark JE, Vesta KS. Pantoprazole-induced thrombocytopenia. Ann Pharmacother. 2006;40(4):758-761.
21. Levy MJ, Seelig CB, Robinson NJ, Ranney JE. Comparison of omeprazole and ranitidine for stress ulcer prophylaxis. Dig Dis Sci. 1997;42(6):1255-1259.
22. Jensen DM, Pace SC, Soffer E, Comer GM; 315 Study Group. Continuous infusion of pantoprazole versus ranitidine for prevention of ulcer rebleeding: a US multicenter randomized, double-blind study. Am J Gastroenterol. 2006;101(9): 1991-1999.
23. Cook D, Heyland D, Griffith L, Cook R, Marshall J, Pagliarello J. Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. Crit Care Med. 1999;27(12): 2812-2817.
24. Pitimana-aree S, Forrest D, Brown G, Anis A, Wang XH, Dodek P. Implementation of a clinical practice guideline for stress ulcer prophylaxis increases appropriateness and decreases cost of care. Intensive Care Med. 1998;24(3):217-223.
25. Mostafa G, Sing RF, Matthews BD, Pratt BL, Norton HJ, Heniford BT. The economic benefit of practice guidelines for stress ulcer prophylaxis. Am Surg. 2002;68(2):146-150.
26. Schupp KN, Schrand LM, Mutnick AH. A cost-effectiveness analysis of stress ulcer prophylaxis. Ann Pharmacother. 2003;37(5):631-635.
27. Yamaguchi Y, Katsumi N, Tauchi M. A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulceration. Aliment Pharmacol Ther. 2005;21(suppl 2):111-115.