There's more than one way to skin a cat: Yet another way to assess mitotic index by cytometry

Cytometry Part A

Volumn 73, Issue 5, 2008, Pages 386-387

  Darzynkiewicz, Zbigniew ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLINE; FLUOROCHROME; HISTONE H3; PHOSPHOPROTEIN; RETINOBLASTOMA PROTEIN;

ANTIGEN EXPRESSION; CELL CYCLE PROGRESSION; CELL LABELING; CHROMATIN; CYTOMETRY; DEPHOSPHORYLATION; DNA REPLICATION; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INTERPHASE; LASER SCANNING CYTOMETRY; LETTER; MITOSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN PHOSPHORYLATION;

BIOLOGICAL MARKERS; CELL CYCLE; FLOW CYTOMETRY; HUMANS; MITOTIC INDEX; NEOPLASMS;

EID: 42949140763     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.20543     Document Type: Letter

References (19)

1. Tapia C, Kutzner H, Mentzel T, Savic S, Baumhoer D, Glatz K. Two mitosis-specific antibodies, MPM-2 and phospho-histone (Ser28) allow rapid and precise determination of mitotic activity. Am J Surg Pathol 2006;30:83-89.
2. Skaland I, Janssen EAM, Gudlaugsson E, Klos J, Kjellevold H, Soland H, Baak JPA. Phosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients less than 55 years of age. Mod Pathol 2007;20:1307-1315.
3. Dematteo RP, Gold JS, Saran L, Gonen M, Liau KH, Maki RG, Singer S, Besnier P, Brennan MF, Antonescu CR. Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST). Cancer 2007; in press. Epub Dec 12, 2007.
4. Gray JW, Darzynkiewicz Z. Techniques in Cell Cycle Analysis. Clifton, NJ: Humana Press; 1987.
5. Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Recognition of cells in mitosis by flow cytofluorometry. J Histochem Cytochem 1977;25:875-880.
6. Darzynkiewicz Z, Traganos F, Melamed MR. New cell cycle compartments identified by multiparameter flow cytometry. Cytometry 1980;1:98-108.
7. 2/M phase subpopulations in mammalian cells nuclei using side light scatter and DNA content measurements. Cytometry 1990;11:813-821.
8. Pfeffer U, Vidali G. A novel protein related to cell cycle-dependent alterations of chromatin structure. Exp Cell Res 1991;193:411-419.
9. Clevenger CV, Epstein AL, Bauer KD. Quantitative analysis of a nuclear antigen in interphase and mitotic cells. Cytometry 1987;8:280-286.
10. Landberg G, Tan EM, Ross G. Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin andKi-67 antigen: A new view on cell cycle. Exp Cell Res 1990;187:111-118.
11. 2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1. Exp Cell Res 1995;220:226-231.
12. Juan G, Pan, Darzynkiewicz Z. DNA segments sensitive to single strand specific nucleases are present in chromatin of mitotic cells. Exp Cell Res 1996;227:197-202.
13. 2 and mitosis. Cytometry 1998;32:71-77.
14. Taagepera S, Rao PN, Drake FH, Gorbsky GJ. DNA topoisomerase IIα is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2. Proc Natl Acad Sci USA 1993;90:8407-8411.
15. Luther E, Kamentsky LA. Resolution of mitotic cells by laser scanning cytometry. Cytometry 1996;23:272-278.
16. Jacobberger JW, Frisa PS, Sramkoski RM, Stefan T, Sholts KE, Soni DV. A new biomarker for mitotic cells. Cytometry Part A 2008;73A:5-15.
17. Juan G, Chang W, Traganos F, Darzynkiewicz Z. Histone H3 phosphorylation in human monocytes and during HL-60 cell differentiation. Exp Cell Res 1999;246:212-229.
18. Gorczyca W, Melamed MR, Darzynkiewicz Z. Laser scanning cytometer analysis of fraction of labeled mitoses. Cell Prolif 1996;29:539-548.
19. Huang X, Kurose A, Tanaka T, Traganos F, Dai W, Darzynkiewicz Z. Sequential phosphorylation of Ser-10 on histone H3 and Ser-139 on histone H2AX and ATM activation during premature chromosome condensation: Relationship to cell-cycle and apoptosis. Cytometry Part A 2006;69A:222-229.