Cardiac and autonomic responses to change in posture or vitamin C supplementation in sickle cell anemia subjects

Pathophysiology

Volumn 15, Issue 1, 2008, Pages 25-30

  Jaja, S I ^a   Kehinde, M O ^a   Ogungbemi, S I ^a  

^a UNIVERSITY OF LAGOS   (Nigeria)

Author keywords

Autonomic; Change in posture; Chronic; Electrocardiogram; Low dose; Sickle cell anemia; Vitamin C

Indexed keywords

ASCORBIC ACID;

ADULT; ARTERIAL PRESSURE; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD PRESSURE MEASUREMENT; BODY POSTURE; CARDIOVASCULAR RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROCARDIOGRAPHY; HEART RATE VARIABILITY; HUMAN; LOW DRUG DOSE; MALE; PR INTERVAL; PRIORITY JOURNAL; QRS COMPLEX; RR INTERVAL; SICKLE CELL ANEMIA; STANDING; SUPINE POSITION; VITAMIN SUPPLEMENTATION;

EID: 42749090820     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pathophys.2007.12.002     Document Type: Article

References (34)

1. Jaja S.I., Aisuodionwe S., Gbenebitse S., and Kehinde M.O. Effect of vitamin C supplementation on vascular responses induced by warmth or cold stimulation in normal Nigerians. Nig. Quart. J. Hosp. Med. 13 (2003) 61-64
2. Jaja S.I., Aisuodionwe S.I., Kehinde M.O., and Gbenebitse S. Effect of vitamin C and/or warmth on forearm blood flow and vascular resistance in sickle cell anemia subjects. Nig. Postgraduate Med. J. 9 (2002) 92-94
3. Koh E.T. Effects of vitamin C on blood parameters of hypertensive subjects. J. Oklahoma State Med. Assoc. 77 (1984) 177-182
4. Trout D.I. Vitamin C and cardiovascular risk factors. Am. J. Clin. Nutr. 53 Suppl. 1 (1991) 322S-325S
5. Osilesi O., Trout D.L., Ogunwole J., and Glover E.E. Blood pressure and plasma lipids during ascorbic acid supplementation in borderline hypertensive and normotensive adults. Nutr. Res. 11 (1991) 405-412
6. Sherman D.L., Keaney J.F., Biegelsen E.S., Duffy S.J., Coffman J.D., and Vita J.A. Pharmacological concentrations of ascorbic acid are required for the beneficial effect on endothelial vasomotor function in hypertension. Hypertension 35 (2000) 936-941
7. Nightingale A.K., Blackman D.J., Field R., Glover N.J., Pegge N., Mumford C., Schmitt M., Ellis G., Morris-Thurgood J., and Frenneaux M. Role of nitric oxide and oxidative stress in baroreceptor dysfunction in patients with chronic heart failure. Clin. Sci. 104 (2003) 529-535
8. Piccirillo G., Nocco M., Moise A., Lionettei M., Naso C., di Carle S., and Marigliano V. Influence of vitamin C on baroreflex sensitivity in chronic heart failure. Hypertension 41 (2003) 1240-1245
9. Monahan K.D., Eskurza I., and Seals D.R. Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am. J. Physiol. Heart Circ. Physiol. 286 (2004) H2113-H2117
10. Paolisso G., D'Amore A., Balbi V., Volpe C., Galzerano D., Gingliano D., Sgambato S., Varricchio M., and D'Onofrio F. Plasma vitamin C affects glucose homeostasis in healthy subjects and in non-insulin-dependent diabetics. Am. J. Physiol. 266 (1994) E261-E268
11. Ting H.H., Timini F.K., Boles K.S., Creager S.J., Gans P., and Creager M.A. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J. Clin. Invest. 97 (1996) 22-28
12. May J.M. How does ascorbic acid prevent endothelial dysfunction?. Free Radic. Biol. Med. 28 (2000) 1421-1429
13. American Heart Association Committee Report, Recommendations for standardization of leads and the specifications for instruments in electrocardiography and vectocardiography, Circulation II, 1957.
14. Anigbogu C.N., and Olubowale O.A. Effects of malaria on blood pressure, heart rate, electrocardiogram and cardiovascular response to change in posture. Nig. Q. J. Hosp. Med. 12 (2002) 17-20
15. Dacie J.V., and Lewis S.M. Practical Hematology. seventh ed. (1991), Livingstone, Edinburgh, Churchill pp. 755-756
16. Anderson J.P.A., Liner M.H., Fredsted A., and Schagatay E.K.A. Cardiovascular and respiratory responses to apneas with and without face immersion in exercising humans. J. Appl. Physiol. 96 (2004) 1005-1010
17. Adigun S.A. Techniques for testing cardiovascular reflexes and the effects of teptrotide, an antihypertensive drug, on some of the reflexes. Nig. J. Physiol. Sci. 2 (1986) 71-72
18. Jespen H., and Gaehtgens P. Postural vascular response vs. sympathetic vasoconstriction in human skin during orthostasis. Am. J. Physiol. (Heart Circ. Physiol. 38) 269 (1998) 53-61
19. Romero-Vecchione E., Perez O., Wessolosky M., Rosa F., Liberatore S., and Vasquez J. Abnormal autonomic cardiovascular responses in patients with sickle cell anemia. Sangre (Barc) 40 (1995) 393-399
20. Hatch F.E., Crowe F.R., Miles D.E., Young J.P., and Portner M.E. Altered vascular reactivity in hemoglobinopathy. A possible protective factor from hypertension. Am. J. Hypertens. 2 (1998) 2-8
21. Romero Mestre J.C., Hernandez A., Agramonte O., and Hernandez P. Cardiovascular autonomic dysfunction in sickle cell anemia: a possible risk factor to sudden death?. Clin. Auton. Res. 7 (1997) 121-125
22. Seshadri S., Shah A., and Bhade S. Hematologic response of anemia in preschool children to ascorbic acid supplementation. Hum. Nutr. Appl. Nutr. 39 (1985) 151-154
23. Ajayi A.O., and Nnaji U.R. Effect of ascorbic acid supplementation on hematological response and ascorbic acid status of young female adults. Ann. Nutr. Metab. 34 (1990) 32-36
24. Jaja S.I., Ikotun A.R., Gbenebitse S., and Temiye E.O. Blood pressure, hematologic and erythrocyte fragility changes in children suffering from sickle cell anemia following ascorbic acid supplementation. J. Trop. Pediatr. 48 (2002) 366-370
25. Jaja S.I., Kehinde M.O., Gbenebitse S., Mojiminiyi F.B.O., and Ogungbemi A.I. Effect of vitamin C on arterial blood pressure, irreversibly sickled cells and osmotic fragility in sickle cell anemia subjects. Nig. J. Physiol. Sci. 16 (2000) 14-18
26. Frei B.L., England L., and Ames B.N. Ascorbate is an outstanding antioxidant in human blood plasma. Proc. Natl. Acad. Sci. USA 86 (1989) 6377-6391
27. Evans W.J. Vitamin E, vitamin C and exercise. Am. J. Clin. Nutr. 72 (2000) 647S-652S
28. Gruetter C.A., Gruetter D.Y., Lyon J.E., Kadowitz P.J., and Ignarro J. Relationship between cyclic guanosine 3′5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrate and nitric oxide: effects of methylene blue and methaemoglobin. J. Pharmacol. Exp. Ther. 219 (1981) 181-186
29. Chowdhary S., and Townend J.N. Role of nitric oxide in the regulation of cardiovascular autonomic control. Clin. Sci. 97 (1999) 5-17
30. Chowdhary S., Vaile J.C., Fletctcher J., Ross H.F., Coote J.H., and Townend J.N. Nitric oxide and cardiac control in humans. Hypertension 36 (2000) 246-269
31. Musialet P., Lei M., Brown H.F., Patterson D.J., and Cassadei B. Nitric oxide can increase heart rate by stimulating the hyperpolarization-activated inward current, I(f). Circ. Res. 81 (1997) 60-68
32. Chowdhary S., Harrington D., Bonser R.S., Coote J.H., and Townend J.N. Chronotropic effects of nitric oxide in the denervated human heart. J. Physiol. 541 (2002) 645-651
33. Ellis G., Anderson R., Lang D., et al. Neutrophil superoxide anion-generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy. J. Am. Coll. Cardiol. 36 (2000) 1474-1482
34. Ettarh R.R., Sofola O.A., and Adigun S.A. Role of endothelium in the vascular effects of vitamin C in rats. Pathophysiol 9 (2003) 97-101