Cardiovascular autonomic dysfunction in sickle cell anemia: A possible risk factor for sudden death?

Clinical Autonomic Research

Volumn 7, Issue 3, 1997, Pages 121-125

  Romero Mestre, J C ^a   Hernandez A ^a   Agramonte, O ^b   Hernandez P ^b  

^a INSTITUTO NACIONAL DE ENDOCRINOLOGÍA   (Cuba)

^b INSTITUTO DE HEMATOLOGÍA E INMUNOLOGÍA   (Cuba)

Author keywords

Cardiovascular autonomic dysfunction; Sickle cell anemia; Spectral analysis

Indexed keywords

ADULT; ARTICLE; AUTONOMIC DYSFUNCTION; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; HEART FUNCTION; HEART RATE VARIABILITY; HUMAN; HYPERPNEA; MAJOR CLINICAL STUDY; MALE; NEGRO; RISK FACTOR; SICKLE CELL ANEMIA; SUDDEN DEATH; VALSALVA MANEUVER;

ADOLESCENT; ADULT; ANEMIA, SICKLE CELL; AUTONOMIC NERVOUS SYSTEM DISEASES; CARDIOVASCULAR DISEASES; DEATH, SUDDEN; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; HEMOGLOBINS; HUMANS; MALE; MIDDLE AGED; RETICULOCYTE COUNT; RISK FACTORS; VALSALVA MANEUVER;

EID: 8544222622     PISSN: 09599851     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02308838     Document Type: Article

References (33)

1. Nagel RL, Fabry ME. The many pathophysiologies of sickle cell anemia. Am J Hematol 1985; 20: 195-199.
2. Singhal A, Doherty JF, Raynes JG et al. Is there an acute-phase response in steady-state sickle cell disease? Lancet 1993; 341: 651-653.
3. Lester LA, Sodt PC, Hutcheon N, Arcilla RA. Cardiac abnormalities in children with sickle cell anemia. Chest 1990; 98: 1169-1174.
4. Maisel A, Friedman H, Flint L, Koshy M, Prabhu R. Continuous electrocardiographic monitoring in patients with sickle-cell anemia during pain crisis. Clin Cardiol 1983; 6: 339-344.
5. Covitz W. Cardiac disease. In: Embury SH, Hebbel RP, Mohandas Steinberg MH, eds. Sickle Cell Disease: Basic Principles and Clinical Practice. New York: Raven Press, 1994; 725-734.
6. Charache S. Sudden death in sickle trait. Am J Med 1988; 84: 459-461.
7. Kark JA, Posey DM, Schumacher HR, Ruehle CJ. Sickle-cell trait as a risk factor for sudden death in physical training. N Engl J Med 1987; 31: 781-787.
8. Liesner RJ, Vanderberghe EA. Sudden death in sickle cell disease. J R Soc Med 1993; 86: 484-485.
9. Platt OS, Brambilla DJ, Rosse WF et al. Mortality in sickle cell disease: life expectancy and risk factors for early death. N Engl J Med 1994; 330: 1639-1644.
10. Thomas AN, Pattison C, Serjeant GR. Causes of death in sickle cell disease in Jamaica. Br Med J 1982; 285: 633-635.
11. Charache S. Sickle cells and sudden death. J Lab Clin Med 1994; 124: 473-474.
12. James TN, Riddick L, Massing GK. Sickle cells and sudden death: morphologic abnormalities of the cardiac conduction system. J Lab Clin Med 1994; 124: 507-520.
13. Ewing DJ, Campbell IW, Clarke BF. The natural history of diabetic autonomic neuropathy. Q J Med 1980; 49: 95-108.
14. Johnson RH, Robinson BJ. Mortality in alcoholics with autonomic neuropathy. J Neurol Neurosurg Psychiatry 1988; 51: 476-480.
15. Page MM, Watkins PJ. Cardiorespiratory arrest and diabetic autonomic neuropathy. Lancet 1978; 1: 14-16.
16. Algotsson A, Viitanen M, Winblad B, Solders G. Autonomic dysfunction in Alzheimer's disease. Acta Neurol Scand 1995; 91: 14-18.
17. Eckardt VF, Stenner F, Liewen H, Röder R, Koop H, Bernhard G. Autonomic dysfunction in patients with achalasia. Neurogastroenterol Mot 1995; 7: 55-61.
18. Ziegler D. Diabetic cardiovascular autonomic neuropathy: prognosis, diagnosis and treatment. Diab Metab Rev 1994; 10: 339-383.
19. Romero-Vecchione E, Perez O, Wessolosky M, Rosa F, Liberatore Vasquez J. Respuestas cardiovasculares autónomas anormales en pacientes con anemia drepanocitica. Sangre 1995; 40: 393-399.
20. Romero JC, Licea M, Faget O, Perich P. Pruebas de función autonómica cardiovascular y duración del intervalo QTc en sujetos fumadores. Rev Esp Cardiol 1996, 49: 259-263.
21. Ziegler D, Laux G, Dannehl K et al. Assessment of cardiovascular autonomic function: age related normal ranges and reproducibility of spectral analysis, vector analysis and standard tests of heart rate variation and blood pressure responses. Diabetic Med 1992; 9: 166-175.
22. Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Chen RJ. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science 1981; 213: 220-222.
23. Lishner M, Akselrod S, MorAvi V, Oz O, Divon M, Ravid M. Spectral analysis of heart rate fluctuations. A non-invasive, sensitive method for the early diagnosis of autonomic neuropathy in diabetes mellitus. J Auton Nerv System 1987; 19: 119-125.
24. Grell GA, Alleyne GAD, Serjeant GR. Blood pressure in adults with homozygous sickle cell disease. Lancet 1981; 2: 1166-1168.
25. Konotey-Ahulu FID. The sickle cell diseases. Clinical manifestations including the 'sickle crisis'. Arch Intern Med 1974; 133: 611-619.
26. Miller GJ, Serjeant GR, Sivapragasam A, Petch MC. Cardiopulmonary responses and gas exchange during exercise in adults with homozygous sickle cell disease. Clin Sci 1973; 44: 113-128.
27. Rathmann W, Ziegler D, Jahnke M, Haastert B, Gries FA. Mortality in diabetic patients with cardiovascular autonomic neuropathy. Diabetic Med 1993; 10: 820-824.
28. Konotey-Ahulu FID. The Sickle Cell Disease Patients. London: Macmillan Education, 1991; 306-317.
29. Hernández P. Mental nerve syndrome in sickle cell anemia. XXII Congress Internat Soc Hematol. Milan, Italy. 1988; 490 (abstr.).
30. Powars D, Chan LS, Schroeder WA. The variable expression of sickle cell disease is genetically determined. Sem Hematol 1990; 27: 360-376.
31. Akinola NO, Stevens SME, Franklin IM, Nash GB, Stuart J. Subclinical ischaemic episodes during the steady state of sickle cell anaemia. J Clin Pathol 1992; 45: 902-906.
32. Senra L, Torres L, Santana C et al. Flujo sanguineo cerebral regional en la enfermedad por hemoglobina S. Empleo del SPECT con 99mPc-HMPAO. Rev Esp Med Nuclear 1993; 12: 318-320.
33. Svarch E, Espinosa E, Hernández P, Martinez G, Ballester J. Resultados de los estudios realizados en Cuba sobre la hemoglobinopatía S. Sangre 1991; 36: 37-42.