Circulating calcification inhibitors and vascular properties in children after renal transplantation

Pediatric Nephrology

Volumn 23, Issue 6, 2008, Pages 985-993

  van Summeren, Marieke J H ^a   Hameleers, Jeroen M ^a   Schurgers, Leon J ^b   Hoeks, Arnold P G ^a   Uiterwaal, Cuno S P M ^b   Krüger, Thilo ^a   Vermeer, Cees ^b   Kuis, Wietse ^c   Lilien, Marc R ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Children; Fetuin A; M mode ultrasound; Matrix Gla protein; Renal transplantation; Vascular properties of carotid artery

Indexed keywords

ANTIHYPERTENSIVE AGENT; FETUIN A; GROWTH HORMONE; MATRIX GLA PROTEIN; MATRIX PROTEIN;

ADOLESCENT; ARTERIAL STIFFNESS; ARTERY CALCIFICATION; ARTERY COMPLIANCE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; CLINICAL ARTICLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; FEMALE; HUMAN; KIDNEY TRANSPLANTATION; LINEAR REGRESSION ANALYSIS; MALE; PEDIATRIC SURGERY; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCHOOL CHILD; STATISTICAL SIGNIFICANCE;

ADOLESCENT; BLOOD PRESSURE; BLOOD PROTEINS; CALCINOSIS; CALCIUM-BINDING PROTEINS; CAROTID ARTERY DISEASES; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; ELASTICITY; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE;

EID: 42649138549     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-007-0743-4     Document Type: Article

References (44)

1. Groothoff JW, Gruppen MP, Offringa M, Hutten J, Lilien MR, Van De Kar NJ, Wolff ED, Davin JC, Heymans HS (2002) Mortality and causes of death of end-stage renal disease in children: A Dutch cohort study. Kidney Int 61:621-629
2. Litwin M, Wuhl E, Jourdan C, Trelewicz J, Niemirska A, Fahr K, Jobs K, Grenda R, Wawer ZT, Rajszys P, Troger J, Mehls O, Schaefer F (2005) Altered morphologic properties of large arteries in children with chronic renal failure and after renal transplantation. J Am Soc Nephrol 16:1494-1500
3. Kiberd B, Keough-Ryan T, Panek R (2003) Cardiovascular disease reduction in the outpatient kidney transplant clinic. Am J Transplant 3:1393-1399
4. Mitsnefes MM, Kimball TR, Witt SA, Glascock BJ, Khoury PR, Daniels SR (2004) Abnormal carotid artery structure and function in children and adolescents with successful renal transplantation. Circulation 110:97-101
5. Groothoff JW, Cransberg K, Offringa M, Van De Kar NJ, Lilien MR, Davin JC, Heymans HS (2004) Long-term follow-up of renal transplantation in children: A Dutch cohort study. Transplantation 78:453-460
6. Guerin AP, London GM, Marchais SJ, Metivier F (2000) Arterial stiffening and vascular calcifications in end-stage renal disease. Nephrol Dial Transplant 15:1014-1021
7. Shanahan CM, Cary NRB, Salisbury JR, Proudfoot D, Weisberg PL, Edmonds ME (1999) Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: Evidence for smooth muscle cell-mediated vascular calcification. Circulation 100:2168-2176
8. Barenbrock M, Kosch M, Joster E, Kisters K, Rahn KH, Hausberg M (2002) Reduced arterial distensibility is a predictor of cardiovascular disease in patients after renal transplantation. J Hypertens 20:79-84
9. Blacher J, Pannier BM, Guerin AP, Marchais SJ, Safar ME, London GM (1998) Carotid arterial stiffness as a predictor of cardiovascular and all-cause mortality in end-stage renal disease. Hypertension 32:570-574
10. O'Leary DH, Polak JF (2002) Intima-media thickness: A tool for atherosclerosis imaging and event prediction. Am J Cardiol 90:18L-21L
11. London GM, Guerin AP, Marchais SJ, Metivier F, Pannier B, Adda H (2003) Arterial media calcification in end-stage renal disease: Impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 18:1731-1740
12. Farzaneh-Far A, Shanahan CM (2005) Biology of vascular calcification in renal disease. Nephron Exp Nephrol 101:e134-e138
13. Ketteler M, Vermeer C, Wanner C, Westenfeld R, Jahnen-Dechent W, Floege J (2002) Novel insights into uremic vascular calcification: Role of matrix Gla protein and alpha-2-Heremans Schmid glycoprotein/fetuin. Blood Purif 20:473-476
14. Proudfoot D, Shanahan CM (2006) Molecular mechanisms mediating vascular calcification: Role of matrix Gla protein. Nephrology 11:455-461
15. Hackeng TM, Rosing J, Spronk HM, Vermeer C (2001) Total chemical synthesis of human matrix Gla protein. Protein Sci 10:864-870
16. Price PA, Urist MR, Otawara Y (1983) Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone. Biochem Biophys Res Commun 117:765-771
17. Sweatt A, Sane DC, Hutson SM, Wallin R (2003) Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats. J Thromb Haemost 1:178-185
18. Price PA, Nguyen TM, Williamson MK (2003) Biochemical characterization of the serum fetuin-mineral complex. J Biol Chem 278:22153-22160
19. Reynolds JL, Skepper JN, McNair R, Kasama T, Gupta K, Weissberg PL, Jahnen-Dechent W, Shanahan CM (2005) Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. J Am Soc Nephrol 16:2920-2930
20. Moe SM, Reslerova M, Ketteler M, O'Neill K, Duan D, Koczman J, Westenfeld R, Jahnen-Dechent W, Chen NX (2005) Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD). Kidney Int 67:2295-2304
21. Schurgers LJ, Teunissen KJ, Knapen MH, Kwaijtaal M, van Diest R, Appels A, Reutelingsperger CP, Cleutjens JP, Vermeer C (2005) Novel conformation-specific antibodies against matrix gamma-carboxyglutamic acid (Gla) protein: Undercarboxylated matrix Gla protein as marker for vascular calcification. Arterioscler Thromb Vasc Biol 25:1629-1633
22. Brancaccio D, Biondi ML, Gallieni M, Turri O, Galassi A, Cecchini F, Russo D, Andreucci V, Cozzolino M (2005) Matrix GLA protein gene polymorphisms: Clinical correlates and cardiovascular mortality in chronic kidney disease patients. Am J Nephrol 25:548-552
23. Farzaneh-Far A, Davies JD, Braam LA, Spronk HM, Proudfoot D, Chan SW, O'Shaughnessy KM, Weissberg PL, Vermeer C, Shanahan CM (2001) A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. J Biol Chem 276:32466-32473
24. Ketteler M, Bongartz P, Westenfeld R, Wildberger JE, Mahnken AH, Böhm R, Metzger T, Wanner C, Jahnen-Dechent W, Floege J (2003) Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: A cross-sectional study. Lancet 361:827-833
25. Wang AY, Woo J, Lam CW, Wang M, Chan IH, Gao P, Lui SF, Li PK, Sanderson JE (2005) Associations of serum fetuin-A with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients. Nephrol Dial Transplant 20:1676-1685
26. Frederiks AM, van Buuren S, Burgmeijer RJF, Verloove-Vanhorick SP, Wit JM (1998) Nederlandse groeidiagrammen in historisch perspectief. In Wit JM (ed) De Vierde Landelijke Groeistudie 1997. Presentatie nieuwe groeidiagrammen
27. Kool MJ, Van Merode T, Reneman RS, Hoeks AP, Struyker Boudier HA, Van Bortel LM (1994) Evaluation of reproducibility of a vessel wall movement detector system for assessment of large artery properties. Cardiovasc Res 28:610-614
28. Stadler RW, Taylor JA, Lees RS (1997) Comparison of B-mode M-mode and echo-tracking methods for measurement of the arterial distension waveform. Ultrasound Med Biol 23:879-887
29. Hoeks APG, Willekes C, Boutouyrie P, Brands PJ, Willigers JM, Reneman RS (1997) Automated detection of local artery wall thickness based on M-line signal processing. Ultrasound Med Biol 23:1017-1023
30. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555-576
31. Braam LAJLM, Dissel P, Gijsbers BLMG, Spronk HMH, Hamulyàk K, Soute BAM, Debie W, Vermeer C (2000) Assay for human matrix Gla protein in serum; potential applications in the cardiovascular field. Arterioscler Thromb Vasc Biol 20:1257-1261
32. Spronk HMH, Soute BAM, Schurgers LJ, Cleutjens JP, Thijssen HHW De Mey JG, Vermeer C (2001) Matrix Gla protein accumulates at the border of regions of calcification and normal tissue in the media of the arterial vessel wall. Biochem Biophys Res Commun 289:485-490
33. Schafer C, Heiss A, Schwarz A, Westenfeld R, Ketteler M, Floege J, Muller-Esterl W, Schinke T, Jahnen-Dechent W (2003) The serum protein {alpha}2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest 112:357-366
34. Schurgers LJ, Teunissen KJ, Knapen MH, Geusens P, van der Heijde D, Kwaijtaal M, van Diest R, Ketteler M, Vermeer C (2005) Characteristics and performance of an immunosorbent assay for human matrix Gla-protein. Clin Chim Acta 351:131-138
35. Jono S, Ikari Y, Vermeer C, Dissel P, Hasegawa K, Shioi A, Taniwaki H, Kizu A, Nishizawa Y, Saito S (2004) Matrix Gla protein is associated with coronary artery calcification as assessed by electron-beam computed tomography. Thromb Haemost 91:790-794
36. Mazzaferro S, Pasquali M, Pugliese F, Barresi G, Carbone I, Francone M, Sardella D, Taggi F (2007) Serum levels of calcification inhibition proteins and coronary artery calcium score: Comparison between transplantation and dialysis. Am J Nephrol 27:75-83
37. Civilibal M, Caliskan S, Adaletli I, Oflaz H, Sever L, Candan C, Canpolat N, Kasapcopur O, Kuruoglu S, Arisoy N (2006) Coronary artery calcifications in children with end-stage renal disease. Pediatr Nephrol 21:1426-1433
38. Groothoff JW, Gruppen MP, Offringa M, de Groot E, Stok W, Bos WJ, Davin JC, Lilien MR, van de Kar NCAJ, Wolff ED, Heymans HS (2002) Increased arterial stiffness in young adults with end-stage renal disease since childhood. J Am Soc Nephrol 13:2953-2961
39. Goodman WG, Goldin J, Kuizon BD, Yoon C, Gales B, Sider D, Wang Y, Chung J, Emerick A, Greaser L, Elashoff RM, Salusky IB (2000) Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 342:1478-1483
40. Wallin R, Sane DC, Hutson SM (2002) Vitamin K 2,3-epoxide reductase and the vitamin K-dependent gamma-carboxylation system. Thromb Res 108:221-226
41. Price PA, Faus SA, Williamson MK (1998) Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves. Arterioscler Thromb Vasc Biol 18:1400-1407
42. Luo G, Ducy P, McKee MD, Pinero GJ, Loyers E, Behringer RR, Karsenty G (1997) Spontaneous calcification of arteries and cartilage in mice lacking matrix Gla protein. Nature 386:78-81
43. Braam LA, Hoeks AP, Brouns F, Hamulyak K, Gerichhausen MJ, Vermeer C (2004) Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: A follow-up study. Thromb Haemost 91:373-380
44. Pilkey RM, Morton AR, Boffa MB, Noordhof C, Day AG, Su Y, Miller LM, Koschinsky ML, Booth SL (2007) Subclinical Vitamin K Deficiency in Hemodialysis Patients. Am J Kidney Dis 49:432-439