Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production

Vascular Medicine

Volumn 13, Issue 1, 2008, Pages 29-36

  Nandi, Manasi ^a   Kelly, Peter ^a   Vallance, Patrick ^a,b   Leiper, James ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cytokines; Endothelial cells; Lipopolysaccharide; Nitric oxide

Indexed keywords

CYTOKINE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I FEEDBACK REGULATORY PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MYC PROTEIN; NITRIC OXIDE; REGULATOR PROTEIN; TETRAHYDROBIOPTERIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; BIOPTERIN; CELL LINE; ENDOTHELIAL CELLS; ENZYME INDUCTION; GENETIC VECTORS; GTP CYCLOHYDROLASE; HUMANS; INTERFERON TYPE II; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SUPEROXIDES; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 42649137529     PISSN: 1358863X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1358863X07085916     Document Type: Article

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