Coordinated expression of clustered cancer/testis genes encoded in a large inverted repeat DNA structure

Gene

Volumn 415, Issue 1-2, 2008, Pages 68-73

  Bredenbeck, Anne ^a,b   Hollstein, Verena M ^a   Trefzer, Uwe ^a   Sterry, Wolfram ^a   Walden, Peter ^a   Losch, Florian O ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Cancer testis antigens; Chromatin structure; CSAG; Double cruciform DNA structure; MAGE

Indexed keywords

CANCER TESTIS ANTIGEN; MESSENGER RNA;

ARTICLE; CSAG GENE; DNA STRUCTURE; GENE; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE LOCATION; GENE REARRANGEMENT; GENETIC ORGANIZATION; HUMAN; HUMAN CELL; INVERTED REPEAT; MAGEA GENE; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN FAMILY; X CHROMOSOME;

ANTIGENS, NEOPLASM; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, X; CLUSTER ANALYSIS; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MELANOMA; NEOPLASMS; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; TESTIS;

EID: 42649132028     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.02.019     Document Type: Article

References (26)

1. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403-410
2. Artamonova II, and Gelfand M.S. Evolution of the exon-intron structure and alternative splicing of the MAGE-A family of cancer/testis antigens. J. Mol. Evol. 59 (2004) 620-631
3. Bacolla A., et al. Breakpoints of gross deletions coincide with non-B DNA conformations. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 14162-14167
4. Chomez P., De Backer O., Bertrand M., De Plaen E., Boon T., and Lucas S. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 61 (2001) 5544-5551
5. Coral S., et al. 5-aza-2′-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications. Clin. Cancer Res. 8 (2002) 2690-2695
6. De Plaen E., et al. Structure, chromosomal localization, and expression of 12 genes of the MAGE family. Immunogenetics 40 (1994) 360-369
7. De Smet C., De Backer O., Faraoni I., Lurquin C., Brasseur F., and Boon T. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 7149-7153
8. Duan Z., Feller A.J., Toh H.C., Makastorsis T., and Seiden M.V. TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line. Gene 229 (1999) 75-81
9. Feller A.J., Duan Z., Penson R., Toh H.C., and Seiden M.V. TRAG-3, a novel cancer/testis antigen, is overexpressed in the majority of melanoma cell lines and malignant melanoma. Anticancer Res. 20 (2000) 4147-4151
10. Lin C., et al. Cancer/testis antigen CSAGE is concurrently expressed with MAGE in chondrosarcoma. Gene 285 (2002) 269-278
11. Losch F.O., Bredenbeck A., Hollstein V.M., Walden P., and Wrede P. Evidence for a large double-cruciform DNA structure on the X chromosome of human and chimpanzee. Hum. Genet. 122 (2007) 337-343
12. Lucas S., Brasseur F., and Boon T. A new MAGE gene with ubiquitous expression does not code for known MAGE antigens recognized by T cells. Cancer Res. 59 (1999) 4100-4103
13. Lucas S., De Plaen E., and Boon T. MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression. Int. J. Cancer 87 (2000) 55-60
14. Lurquin C., et al. Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins. Genomics 46 (1997) 397-408
15. Muscatelli F., Walker A.P., De Plaen E., Stafford A.N., and Monaco A.P. Isolation and characterization of a MAGE gene family in the Xp21.3 region. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 4987-4991
16. Ohta M., Tanaka F., Sadanaga N., Yamaguchi H., Inoue H., and Mori M. Expression of the TRAG-3 gene in human esophageal cancer: the frequent synchronous expression of MAGE-3 gene. Oncol. Rep. 15 (2006) 1529-1532
17. Ross M.T., et al. The DNA sequence of the human X chromosome. Nature 434 (2005) 325-337
18. Sigalotti L., et al. Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma. J. Immunother. 25 (2002) 16-26
19. Sigalotti L., et al. Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine. Cancer Res. 64 (2004) 9167-9171
20. Tolhuis B., Palstra R.J., Splinter E., Grosveld F., and de Laat W. Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol. Cell 10 (2002) 1453-1465
21. van der Bruggen P., et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254 (1991) 1643-1647
22. Vatolin S., et al. Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. Cancer Res. 65 (2005) 7751-7762
23. Warburton P.E., Giordano J., Cheung F., Gelfand Y., and Benson G. Inverted repeat structure of the human genome: the X-chromosome contains a preponderance of large, highly homologous inverted repeats that contain testes genes. Genome Res. 14 (2004) 1861-1869
24. Weber J., et al. Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine. Cancer Res. 54 (1994) 1766-17671
25. Wells R.D. Non-B DNA conformations, mutagenesis and disease. Trends Biochem. Sci. 32 (2007) 271-278
26. Wischnewski F., Friese O., Pantel K., and Schwarzenbach H. Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters. Mol. Cancer Res. 5 (2007) 749-7459