The prognostic impact of occult lymph node metastasis in cancer of the esophagus or esophago-gastric junction: Systematic review and meta-analysis

Diseases of the Esophagus

Volumn 21, Issue 3, 2008, Pages 236-240

  Mcguill, M J ^a   Byrne, Patrick ^a   Ravi, N ^a   Reynolds, J ^a  

^a ST JAMES S HOSPITAL   (Ireland)

Author keywords

Ca esophagus; Lymph node metastasis; Meta analysis

Indexed keywords

ANTINEOPLASTIC AGENT; EOSIN; HEMATOXYLIN;

ADENOCARCINOMA; ADJUVANT THERAPY; CANCER ADJUVANT THERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; COHORT ANALYSIS; DATA BASE; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; EMBASE; ESOPHAGUS CANCER; EVIDENCE BASED MEDICINE; HISTOPATHOLOGY; HUMAN; LOWER ESOPHAGUS SPHINCTER CANCER; LYMPH NODE METASTASIS; MEDLINE; META ANALYSIS; OBSERVATIONAL STUDY; OCCULT CANCER; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE ANALYSIS; REVIEW; SQUAMOUS CELL CARCINOMA; SYSTEMATIC REVIEW;

DISEASE-FREE SURVIVAL; ESOPHAGEAL NEOPLASMS; ESOPHAGOGASTRIC JUNCTION; HUMANS; LYMPHATIC METASTASIS; PROGNOSIS;

EID: 42649127732     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2007.00765.x     Document Type: Review

References (24)

1. American Joint Committee on Cancer. AJCC Cancer Staging Manual, 6th edn. New York: Springer-Verlag, 2002.
2. Hayden J A, Cote P, Bombardier C. Evaluation of the quality of prognosis studies in systematic reviews. Ann Intern Med 2006; 144: 427-37.
3. Higgins J, Green S, (eds). Assessment of Study Quality. Cochrane Handbook for Systematic Reviews of Inter-ventions 4.2.5 [updated May 2005]; Section 6.5, http://www.cochrane.org/resources/handbook/hbook.htm (accessed 4th January 2006).
4. Higgins J, Green S, (eds). Analysing and presenting results. Cochrane Handbook for Systematic Review of Interventions 4.2.5 [Updated May 2005]; Section 8.5.6, http://www.cochrane.org/resources/handbook/ hbook.htm (accessed 4th January 2006).
5. Parmar M K, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 1998; 17: 2815-34.
6. Higgins J, Green S, (eds). Analysing and presenting results. Cochrane Handbook for Systematic Review of Interventions 4.2.5 [updated May 2005]; Section 8.7.2, http://www.cochrane.org/resources/handbook/ hbook.htm (accessed 4th January 2006).
7. Deeks J, Altman D, Bradburn M. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger M, Smith G D, Altman D, (eds). Systematic Reviews in Health Care: Meta-analysis in Context. London: BMJ Publication Group, 2001; 285-312.
8. Glickman J N, Torres C, Wang H H et al. The prognostic significance of lymph node micrometastasis in patients with esophageal carcinoma. Cancer 1999; 85: 769-78.
9. Xiao X-W. Relationship between lymph node metastases in esophageal carcinoma and it prognosis. Chinese J Cancer Res 2002; 14: 297-301.
10. Natsugoe S, Mueller J, Stein H J, Feith M, Hofler H, Siewart J R. Micrometastasis and tumor cell microinvolvement of lymph nodes from esophageal squamous cell carcinoma: Frequency, associated tumor characteristics, and impact on prognosis. Cancer 1998; 83: 858-66.
11. Mueller J D, Stein H J, Oyang T et al. Frequency and clinical impact of lymph node micrometastasis and tumor cell microinvolvement in patients with adenocarcinoma of the esophagogastric junction. Cancer 2000; 89: 1874-82.
12. Heeren P A, Kelder W, Blondeel I, van Westreenen H L, Hollema H, Plukker J T. Prognostic value of nodal micro-metastases in patients with cancer of the gastro-oesophageal junction. Eur J Surg Oncol 2005; 31: 270-6.
13. Matsumoto M, Natsugoe S, Nakashima S et al. Clinical significance of lymph node micrometastasis of pN0 esophageal squamous cell carcinoma. Cancer Lett 2000; 153: 189-97.
14. Sato F, Shimada Y, Li Z, Watanabe G, Maeda M, Imamura M. Lymph node micrometastasis and prognosis in patients with oesophageal squamous cell carcinoma. Br J Surg 2001; 88: 426-32.
15. Vazquez-Sequeiros E, Wang L, Burgart L et al. Occult lymph node metastases as a predictor of tumor relapse in patients with node-negative esophageal carcinoma. Gastroenterology 2002; 122: 1815-21.
16. Nakamura T, Ide H, Eguchi R, Hayashi K, Ota M, Takasaki K. Clinical implications of lymph node micrometastasis in patients with histologically node-negative (pN0) esophageal carcinoma. J Surg Oncol 2002; 79: 224-9.
17. Hosch S, Kraus J, Scheunemann P et al. Malignant potential and cytogenetic characteristics of occult disseminated tumor cells in esophageal cancer. Cancer Res 2000; 60: 6836-40.
18. MacGuill M J, Barrett C, Ravi N, Macdonald G, Reynolds J V. Isolated tumour cells in pathological node-negative lymph nodes (pN0) adversely affect prognosis in cancer of the oesophagus or oesophago-gastric junction. J Clin Pathol 2007; Epub ahead of print.
19. Bonavina L, Incarbone R, Midolo V, Bona D, Ferrero S, Dall'Asta C. Prognostic significance of lymphatic micrometastasis of esophageal adenocarcinoma. Chir Ital 2004; 56: 189-96.
20. Laso C A, Gonzalez J J, Fresno F, Azcano E, Sanz L, Navarrete F. Prognostic value of micrometastases in esophageal and colorectal carcinoma (a clinical experience). Hepatogastroenterology 2004; 51: 964-7.
21. Komukai S, Nishimaki T, Watanabe H. Ajioka Y, Suzuki T, Hatakeyama K. Significance of immunohistochemically demonstrated micrometastases to lymph nodes in esophageal cancer with histologically negative nodes. Surgery 2000; 127: 40-6.
22. Williamson P R, Smith C T, Hutton J L, Marson A G. Aggregate data meta-analysis with time-to-event outcomes. Stat Med 2002; 21: 3337-51.
23. Stroup D F, Berlin J A, Morton S C et al. Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-Anal Observational Studies Epidemiol (MOOSE) Group. JAMA 2000; 283: 2008-12.
24. Egger M, Schneider M, Davey Smith G. Spurious precision? Meta-analysis of observational studies. BMJ 1998; 316: 140-4.