Clinical significance of lymph node micrometastasis of pN0 esophageal squamous cell carcinoma

Cancer Letters

Volumn 153, Issue 1-2, 2000, Pages 189-197

  Matsumoto, Masataka ^a   Natsugoe, Shoji ^a   Nakashima, Saburo ^a   Sakamoto, Fuminori ^a   Okumura, Hiroshi ^a   Sakita, Hironori ^a   Baba, Masamichi ^a   Takao, Sonshin ^a   Aikou, Takashi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Cytokeratin; Esophageal squamous cell carcinoma; Immunohistochemistry; Lymph node micrometastasis; Postoperative recurrence

Indexed keywords

CYCLIN D1; CYTOKERATIN; UVOMORULIN;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; ESOPHAGUS CARCINOMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TUMOR RECURRENCE;

ADULT; AGED; AGED, 80 AND OVER; CADHERINS; CARCINOMA, SQUAMOUS CELL; CYCLIN D1; EPITHELIUM; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS;

EID: 0034729312     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00374-8     Document Type: Article

References (29)

1. Cutait R., Alves V.A.F., Lopes L.C., Cutait D.E., Borges J.L.A., Singer J., da Silva J.H., Goffi F.S. Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins. Dis. Colon Rectum. 34:1991;917-920.
2. Maehara Y., Oshiro T., Endo K., Baba H., Oda S., Ichiyoshi Y., Kohnoe S., Sugimachi K. Clinical significance of occult micrometastases in lymph nodes from patients with early gastric cancer who died of recurrence. Surgery. 119:1995;397-402.
3. Greenson J., Isenhart C.E., Rice R., Mojzisik C., Houchens D., Martin E.W. Identification of occult micrometastases in pericolic lymph nodes of Dukes' B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49: correlation with long-term survival. Cancer. 73:1994;563-569.
4. Clare S.E., Sever S.F., Wilkens W., Goldschmidt R., Merkel D., Winchester D.J. Prognostic significance of occult lymph node metastases in node-negative breast cancer. Ann. Surg. Oncol. 4:1997;447-451.
5. Natsugoe S., Mueller J., Stein H.J., Feith M., Hofler H., Siewert J.R. Micrometastasis and tumor cell microinvolvement of lymph nodes from esophageal squamous cell carcinoma: frequency, associated tumor characteristics, and impact on prognosis. Cancer. 83:1998;858-866.
6. Glickman J.N., Torres C., Wang H.H., Turner J.R., Shahsafaei A., Richards W.G., Sugarbaker D.J., Odze R.D. The prognostic significance of lymph node micrometastasis in patients with esophageal carcinoma. Cancer. 85:1999;769-778.
7. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science. 251:1991;1451-1455.
8. Tamura S., Shiozaki H., Miyata M., Kadowaki T., Inoue M., Matsui S., Iwazawa T., Takayama T., Takeichi M., Monden M. Decreased E-cadherin expression is associated with haematogenous recurrence and poor prognosis in patients with squamous cell carcinoma of the oesophagus. Br. J. Surg. 83:1996;1608-1614.
9. Jiang W., Kahn S.M., Tomita N., Zhang Y.J., Lu S.H., Weinstein I.B. Amplification and expression of the human cyclin D gene in esophageal cancer. Cancer Res. 52:1992;2980-2983.
10. Tsuruta H., Sakamoto H., Onda M., Terada M. Amplification and overexpression of EXP1 and EXP2/cyclin D1 genes in human esophageal carcinomas. Biochem. Biophys. Res. Commun. 196:1993;1529-1536.
11. Sobin L.H., Wittekind C. TNM classification of malignant tumors. 5th Edition International Union Against Cancer. 1997;Wiley, New York.
12. Woodcock M.J., Eichner R., Nelson W.G., Sun T.T. Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J. Cell Biol. 95:1982;580-588.
13. Listrom M.B., Dalton L.W. Comparison of keratin monoclonal antibodies MAK-6 AE1:AE3, and CAM-5.2. Am. J. Clin. Pathol. 88:1987;297-301.
14. Cordell J.L., Falini B., Erber W.N., Ghosh A.K., Abdulaziz Z., MacDonald S., Pulford K.A., Stein H., Manson D.Y. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J. Histochem. Cytochem. 32:1984;219-229.
15. Bartkova J., Lukas J., Strauss M., Bartek J. Cell cycle-related variation and tissue-restricted expression of human cyclin D1 protein. J. Pathol. 172:1994;237-245.
16. Shimoyama Y., Hirohashi S., Hirano S., Noguchi M., Shimosato Y., Takeichi M., Abe O. Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res. 49:1989;2128-2133.
17. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
18. Wang L.D., Shi S.T., Zhou Q., Goldstein S., Hong J.Y., Shao P., Qiu S.L., Yang C.S. Changes in p53 and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric-cardia carcinogenesis. Int. J. Cancer. 59:1994;514-519.
19. Shiozaki H., Tahara H., Oka H., Miyata M., Kobayashi K., Tamura S., Iihara K., Doki Y., Hirano S., Takeichi M., Mori T. Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am. J. Pathol. 139:1991;17-23.
20. Robery-Cafferty S.S., El-Naggar A.K., Sahin A.A., Bruner J.M., Ro J.Y., Cleary K.R. Prognostic factors in esophageal squamous carcinoma. Am. J. Clin. Pathol. 95:1991;844-849.
21. Roder J.D., Busch R., Stein H.J., Fink U., Siewert J.R. Ratio of invaded to removed lymph nodes as a predictor of survival in squamous cell carcinoma of the esophagus. Br. J. Surg. 81:1994;410-413.
22. Natsugoe S., Aiko T., Shimazu H. A detailed histological study on occult metastasis of the lymph nodes. Jpn. J. Surg. 21:1991;528-532.
23. Isozaki H., Okajima K., Fujii K. Histological evaluation of lymph node metastasis on serial sectioning in gastric cancer with radical lymphadenectomy. Hepatogastroenterology. 44:1997;1133-1136.
24. Izbicki J.R., Hosch S.B., Pichlmeier U., Rehders A., Busch C., Niendorf A., Passlick B., Broelsch C.E., Pantel K. Prognostic value of immunohistochemically identifiable tumor cells in lymph nodes of patients with completely resected esophageal cancer. N. Engl. J. Med. 337:1997;1188-1194.
25. Inomata M., Uchino S., Tanimura H., Shiraishi N., Adachi Y., Kitano S. Amplification and overexpression of cyclin D1 in aggressive human esophageal cancer. Oncol. Rep. 5:1998;171-176.
26. Takeuchi H., Ozawa S., Ando N., Shih C.H., Koyanagi K., Ueda M., Kitajima M. Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus. Clin. Cancer. Res. 3:1997;2229-2236.
27. Shinozaki H., Ozawa S., Ando N., Tsuruta H., Terada M., Ueda M., Kitajima M. Cyclin D1 amplification as a new predictive classification for squamous cell carcinoma of the esophagus, adding gene information. Clin. Cancer. Res. 2:1996;1155-1161.
28. Ishikawa T., Furihata M., Ohtsuki Y., Murakami H., Inoue A., Ogoshi S. Cyclin D1 overexpression related to retinoblastoma protein expression as a prognostic marker in human oesophageal squamous cell carcinoma. Br. J. Cancer. 77:1998;92-97.
29. Kadowaki T., Shiozaki H., Inoue M., Tamura S., Oka H., Doki Y., Iihara K., Matsui S., Iwazawa T., Nagafuchi A., Tsukita S., Mori T. E-cadherin and alpha-catenin expression in human esophageal cancer. Cancer Res. 54:1994;291-296.