High affinity interactions between red blood cell receptors and synthetic Plasmodium thrombospondin-related apical merozoite protein (PTRAMP) peptides

Biochimie

Volumn 90, Issue 5, 2008, Pages 802-810

  Calderón, Juan Carlos ^a   Curtidor, Hernando ^a   González, Oscar ^a   Cifuentes, Gladys ^a   Reyes, Claudia ^a   Patarroyo, Manuel E ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

HABP; Plasmodium falciparum; PTRAMP; Thrombospondin

Indexed keywords

CELL RECEPTOR; HIGH ACTIVITY BINDING PEPTIDE; MEROZOITE SURFACE PROTEIN 1; THROMBOSPONDIN;

ARTICLE; BINDING ASSAY; CIRCULAR DICHROISM; CONTROLLED STUDY; DISSOCIATION CONSTANT; ERYTHROCYTE; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PLASMODIUM FALCIPARUM; PROTEIN DOMAIN; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; ERYTHROCYTE MEMBRANE; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMODIUM; PROTEIN BINDING; PROTOZOAN PROTEINS; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID;

PLASMODIUM FALCIPARUM;

EID: 42649126706     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2007.11.012     Document Type: Article

References (46)

1. Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., and Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434 (2005) 214-217
2. Greenwood B., and Mutabingwa T. Malaria in 2002. Nature 415 (2002) 670-672
3. Bannister L., and Mitchell G. The ins, outs and roundabouts of malaria. Trends Parasitol 19 (2003) 209-213
4. Bushell G.R., Ingram L.T., Fardoulys C.A., and Cooper J.A. An antigenic complex in the rhoptries of Plasmodium falciparum. Mol. Biochem. Parasitol. 28 (1988) 105-112
5. Sim B.K., Chitnis C.E., Wasniowska K., Hadley T.J., and Miller L.H. Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum. Science 264 (1994) 1941-1944
6. Carruthers V.B., and Blackman M.J. A new release on life: emerging concepts in proteolysis and parasite invasion. Mol. Microbiol. 55 (2005) 1617-1630
7. Tucker R.P. The thrombospondin type 1 repeat superfamily. Int. J. Biochem. Cell Biol. 36 (2004) 969-974
8. Thompson J., Cooke R.E., Moore S., Anderson L.F., Janse C.J., and Waters A.P. PTRAMP; a conserved Plasmodium thrombospondin-related apical merozoite protein. Mol. Biochem. Parasitol. 134 (2003) 225-232
9. Green J.L., Hinds L., Grainger M., Knuepfer A., and Holder A.A. Plasmodium thrombospondin related apical merozoite protein (PTRAMP) is shed from the surface of merozoites by PfSUB2 upon invasion of erythrocytes. Mol. Biochem. Parasitol. 150 (2006) 114-117
10. Kappe S., Bruderer T., Gantt S., Fujioka H., Nussenzweig V., and Menard R. Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites. J. Cell Biol. 147 (1999) 937-943
11. Urquiza M., Rodríguez L.E., Suárez J.E., Guzmán F., Ocampo M., Curtidor H., Segura C., Trujillo E., and Patarroyo M.E. Identification of Plasmodium falciparum MSP-1 peptides able to bind to human red blood cells. Parasite Inmunol 18 (1996) 515-526
12. Espejo F., Bermudez A., Torres E., Urquiza M., Rodriguez R., Lopez Y., and Patarroyo M.E. Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria. Biochem. Biophys. Res. Commun. 315 (2004) 418-427
13. Houghten R.A. General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl. Acad. Sci. 82 (1985) 5131-5135
14. Merrifield R.B. Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J. Am. Chem. Soc. 85 (1963) 2149-2154
15. Tam J.P., Heath W.F., and Merrifield R.B. SN 1 and SN 2 mechanisms for the deprotection of synthetic peptides by hydrogen fluoride. Studies to minimise the tyrosine alkylation side reaction. Int. J. Pept. Protein Res. 21 (1983) 57-65
16. Yamamura H.I., Enna S.J., and Kujar M.J. Neurotransmitter Receptor Binding (1998), Raven Press, New York
17. Curtidor H., Urquiza M., Suarez J.E., Rodríguez L.E., Ocampo M., Puentes A., Garcia J.E., Vera R., Lopez R., Ramirez L.E., Pinzon M., and Patarroyo M.E. Plasmodium falciparum acid basic repeat antigen (ABRA) peptides: erythrocyte binding and biological activity. Vaccine 19 (2001) 4496-4504
18. Lambros C., and Vanderberg J.P. Synchronization of Plasmodium falciparum erythrocyte stages in culture. J. Parasitol. 65 (1979) 418-420
19. Wyatt C.R., Goff W., and Davis W.C. A flow cytometric method for assessing viability of intraerythrocytic hemoparasites. J. Immunol. Methods 140 (1991) 23-30
20. Compton L.A., and Johnson W.C. Analysis of protein circular dichroism spectra for secondary structure using a simple matrix multiplication. Anal. Biochem. 155 (1986) 155-167
21. Sreerama N., Venyaminov S.Y., and Woody R.W. Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy. Protein Sci 8 (1999) 370-380
22. Combet C., Jambon M., Deleage G., and Geourjon C. Geno 3D: automatic comparative molecular modelling of protein. Bioinformatics 18 (2002) 213-214
23. López R., Curtidor H., Urquiza M., García J., Puentes A., Suárez J., Ocampo M., Vera R., Rodríguez L.E., Castillo F., Cifuentes G., and Patarroyo M.E. Plasmodium falciparum: binding studies of peptide derived from the sporozoite surface protein 2 to Hep G2 cells. J. Pept. Res. 58 (2001) 285-292
24. Suárez J.E., Urquiza M., Puentes A., García J.E., Curtidor H., Ocampo M., López R., Rodríguez L.E., Vera R., Cubillos M., Torres M.H., and Patarroyo M.E. Plasmodium falciparum circumsporozoite (CS) protein peptides specifically bind to HepG2 cells. Vaccine 19 (2001) 4487-4495
25. Tossavainen H., Pihlajamaa T., Huttunen T.K., Raulo E., Rauvala H., Permi P., and Kilpeläinen I. The layered fold of the TSR domain of TRAP P. falciparum contains a heparine binding site. Prot. Sci. 15 (2006) 1760-1768
26. Rodriguez L.E., Urquiza M., Ocampo M., Suarez J., Curtidor H., Guzman F., Vargas L.E., Trivinos M., Rosas M., and Patarroyo M.E. Plasmodium falciparum EBA-175 kDa protein peptides which bind to human red blood cells. Parasitology 120 (2000) 225-235
27. Marti M., Good R.T., Rug M., Knuepfer E., and Cowman A.F. Targeting malaria virulence and remodeling proteins to the host erythrocyte. Science 306 (2004) 1930-1933
28. Hulme E.C. Receptor-Ligand Interactions: A Practical approach (1993), IRL Press, Oxford
29. Woody R.W. Circular dichroism. Methods Enzymol 245 (1995) 34-71
30. Frevert U., Sinnis P., Cerami C., Shreffler W., Takacs B., and Nussenzweig V. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. J. Exp. Med. 177 (1993) 1287-1298
31. Chen H., Herndon M.E., and Lawler J. The cell biology of thrombospondin-1. Matrix Biol 19 (2000) 597-614
32. Silverstein R.L. The face of TSR revealed: an extracellular signaling domain is exposed. J. Cell Biol. 159 (2002) 203-206
33. Tan K., Duquette M., Liu J.H., Dong Y., Zhang R., Joachimiak A., Lawer J., and Wang J.H. Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication. J. Cell Biol. 159 (2002) 373-382
34. Klar A., Baldassare M., and Jessell T.M. F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69 (1992) 95-110
35. Adams J.C., and Tucker R.P. The thrombospondin type 1 repeat (TSR) superfamily: diverse proteins with related roles in neuronal development. Dev. Dyn. 218 (2000) 280-299
36. Kilpelainen I., Kaksonen M., Avikainen H., Fath M., Linhardt R.J., Raulo E., and Rauvala H. Heparin-binding growth-associated molecule contains two heparin-binding beta-sheet domains that are homologous to the thrombospondin type I repeat. J. Biol. Chem. 275 (2000) 13564-13570
37. Ménard R. Gliding motility and cell invasion by Apicomplexa: insights from the Plasmodium sporozoite. Cell Microbiol 3 (2001) 63-73
38. Cerami C., Frevert U., Sinnis P., Takacs B., Clavijo P., Santos M.J., and Nussenzweig V. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites. Cell 70 (1992) 1021-1033
39. Baum J., Richard D., Healer J., Rug M., Krnajski Z., Gilberger T.W., Green J.L., Holder A.A., and Cowman A.F. A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites. J. Biol. Chem. 281 (2006) 5197-5208
40. Chattopadhyay R., Rathore D., Fujioka H., Kumar S., de la Vega P., Haynes D., Moch K., Fryauff D., Wang R., Carucci D.J., and Hoffman S.L. PfSPATR; a Plasmodium falciparum protein containing an altered thrombospondin type I repeat domain is expressed at several stages of the parasite life cycle and is the target of inhibitory antibodies. J. Biol. Chem. 278 (2003) 25977-25981
41. Menard R., Sultan A.A., Cortes C., Altszuler R., van Dijk M.R., Janse C.J., Waters A.P., Nussenzweig R.S., and Nussenzweig V. Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes. Nature 385 (1997) 336-340
42. Lopez R., Urquiza M., Curtidor H., Eduardo Caminos J., Mora H., Puentes A., and Patarroyo M.E. Plasmodium falciparum: red blood cell binding studies of peptides derived from histidine-rich KAHRP-I, HRP-II and HRP-III proteins. Acta Trop 75 3 (2000 May 31) 349-359
43. Cifuentes G., Patarroyo M.E., Reyes C., Cortes J., and Patarroyo M.A. A pre-PEXEL histidine-rich protein II erythrocyte binding peptide as a new way for anti-malarial vaccine development. Biochem. Biophys. Res. Commun. 360 (2007) 149-155
44. Curtidor H., Torres M.H., Alba M.P., and Patarroyo M.E. Structural modifications to a high-activity binding peptide located within the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys. Biol. Chem. 388 (2007) 25-36
45. Baum J., Maier A.G., Good R.T., Simpson K.M., and Cowman A.F. Invasion by P. falciparum merozoites suggests a hierarchy of molecular interactions. Plos Pathog 4 (2005) 299-309
46. Espejo F., Cubillos M., Salazar L.M., Guzman F., Urquiza M., Ocampo M., Silva Y., Rodriguez R., Lioy E., and Patarroyo M.E. Structure, immunogenicity, and protectivity relationship for the 1585 malarial peptide and its substitution analogues. Angew Chem. Int. Ed. Engl. 40 (2001) 4654-4657