Gene cloning and characterization of a second alanine racemase from Bacillus subtilis encoded by yncD

FEMS Microbiology Letters

Volumn 283, Issue 1, 2008, Pages 69-74

  Pierce, Kara J ^a,b   Salifu, Samson P ^a   Tangney, Martin ^a  

^a EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

^b BioReliance Ltd   (United Kingdom)

Author keywords

Alanine racemase; Auxotroph; Bacillus subtilis

Indexed keywords

ALANINE RACEMASE;

ANIMAL CELL; ARTICLE; AUXOTROPHIC MUTANT; BACILLUS SUBTILIS; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL FREE SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENETIC CODE; GENETIC IDENTIFICATION; GENETIC TRAIT; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; YNCD GENE;

ALANINE RACEMASE; AMINO ACID SEQUENCE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; CLONING, MOLECULAR; ESCHERICHIA COLI; MOLECULAR SEQUENCE DATA; PHYLOGENY;

BACILLUS SUBTILIS; ESCHERICHIA COLI;

EID: 42649113739     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2008.01151.x     Document Type: Article

References (20)

1. Bron PA, Benchimol MG, Lambert J, Palumbo E, Deghorain M, Delcour J, De Vos WM, Kleerebezem M Hols P (2002) Use of the alr gene as a food-grade selection marker in lactic acid bacteria. Appl Environ Microbiol 68 : 5663 5670.
2. Diderichsen B (1986) A genetic system for stabilization of cloned genes in Bacillus subtilis. Bacillus Molecular Genetics and Biotechnology Applications (Gansean A Hoch JA, eds pp. 35 46. Academic press, New York.
3. Ferrari E, Henner DJ Yang MY (1985) Isolation of an alanine racemase gene from Bacillus subtilis and its use for plasmid maintenance in B. subtilis. Bio/Technol 3 : 1003 1007.
4. Hols P, Defrenne C, Ferain T, Derzelle S, Delplace B Delcour J (1997) The alanine racemase gene is essential for growth of Lactobacillus plantarum. J. Bacteriol 179 : 3804 3807.
5. Inagaki KB, Badet B, Walsh CT, Tanaka H Soda K (1986) Thermostable alanine racemase from Bacillus stearothermophilus: molecular cloning of the gene, enzyme purification, and characterization. Biochem 25 : 3268 3274.
6. Nicholas KB, Nicholas HB Jr. Deerfield DW II. (1997) GeneDoc: analysis and visualization of genetic variation. EMB News 4 : 14
7. Noda M, Kawahara Y, Ichikawa A, Matoba Y, Matsuo H, Lee DG, Kumagai T Sugiyama M (2004) Self-protection mechanism in d-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization and kinetics of its alanine racemase and d-alanyl-d-alanine ligase which are target enzymes of d-cycloserine. J Biol Chem 279 : 46143 46152.
8. Page RDM (1996) TREEVIEW: an application to display phylogenetic trees on personal computers. Comp Appl Biosci 12 : 357 358.
9. Palumbo E, Favier CF, Deghorain M, Cocconcelli PS, Grangette C, Mercenier A, Vaughan EE Hols P (2004) Knockout of the alanine racemase gene in Lactobacillus plantarum results in septation defects and cell wall perforation. FEMS Microbiol Lett 233 : 131 138.
10. Strych U, Huang HC, Krause KL Benedik MJ (2000) Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Curr Microbiol 41 : 290 294.
11. Strych U, Penland RL, Jimenez M, Krause KL Benedik MJ (2001) Characterization of the alanine racemases from two Mycobacteria. FEMS Microbiol Lett 196 : 93 98.
12. Tangney M, Buchanan CJ, Priest FG Mitchell WJ (1992a) Maltose uptake and its regulation in Bacillus subtilis. FEMS Microbiol Lett 97 : 191 196.
13. Tangney M, Smith P, Priest FG Mitchell WJ (1992b) Maltose transport in Bacillus licheniformis NCIB 6346. J Gen Microbiol 138 : 1821 1827.
14. Tanizawa K, Ohshima A, Scheidegger A, Inagaki K, Tanaka H Soda K (1988) Thermostable alanine racemase from Bacillus stearothermophilus: DNA and protein sequence determination and secondary structure prediction. Biochem 27 : 1311 1316.
15. Tauch A, Gotker S, Puhler A, Kalinowski J Thierbach G (2002) The alanine racemase gene alr is an alternative to antibiotic resistance genes in cloning systems for industrial Corynebacterium glutamicum strains. J Biotechnol 99 : 79 91.
16. Thompson A, Griffin H Gasson MJ (2002) Characterization of an alanine racemase gene from Lactobacillus reuteri. Curr Microbiol 44 : 246 250.
17. Walsh CT (1989) Enzymes in the d-alanine branch of bacterial cell wall peptidoglycan assembly. J Biol Chem 264 : 2393 2396.
18. Wasserman SA, Walsh CT Botstein D (1983) Two alanine racemase genes in Salmonella typhimurium that differ in structure and function. J Bacteriol 153 : 1439 1450.
19. Watanabe A, Yoshimura T, Mikami B Esaki N (1999) Tyrosine 265 of alanine racemase serves as a base abstracting alpha-hydrogen from l-alanine: the counterpart residue to lysine 39 specific to d-alanine. J Biochem 126 : 781 786.
20. Wild J, Hennig J, Lobocka M, Walczak W Klopotowski T (1985) Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12. Mol Gen Genet 198 : 315 322.