-
1
-
-
2942608807
-
-
New York: Springer
-
Simon, R.M.; Korn, E.L.; McShane, L.M.; Radmacher, M.D.; Wright, G.W.; Zhao, Y. Design and Analysis of DNA Microarray Investigations. New York: Springer, 2003.
-
(2003)
Design and Analysis of DNA Microarray Investigations
-
-
Simon, R.M.1
Korn, E.L.2
McShane, L.M.3
Radmacher, M.D.4
Wright, G.W.5
Zhao, Y.6
-
2
-
-
0037041631
-
Identifying pre-post chemotherapy differences in gene expression in breast tumors: A statistical method appropriate for this aim
-
Korn, E.L.; McShane, L.M.; Troendle, I.F.; Rosenwald, A.; Simon, R. Identifying pre-post chemotherapy differences in gene expression in breast tumors: a statistical method appropriate for this aim. Br J Cancer 2002; 86, 1093-1096.
-
(2002)
Br J Cancer
, vol.86
, pp. 1093-1096
-
-
Korn, E.L.1
McShane, L.M.2
Troendle, I.F.3
Rosenwald, A.4
Simon, R.5
-
3
-
-
24344444819
-
Gene expression patterns and profile changes pre- and post-Erlotinib treatment in patients with metastatic breast cancer
-
Yang, S.X.; Simon, R.M.; Tan, A.R.; Nguyen, D.; Swain, S.M. Gene expression patterns and profile changes pre- and post-Erlotinib treatment in patients with metastatic breast cancer. Clin Cancer Res 2005, 11, 6226-6232.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6226-6232
-
-
Yang, S.X.1
Simon, R.M.2
Tan, A.R.3
Nguyen, D.4
Swain, S.M.5
-
4
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population based study
-
Sotiriou, C.; Neo, S.Y.; McShane, L.M.; et al. Breast cancer classification and prognosis based on gene expression profiles from a population based study. Proc Natl Acad Sci USA 2003, 100(18), 10393-10398.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.18
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
-
5
-
-
0037076342
-
Initiating oncogenic event determines gene-expression patterns of human breast cancer models
-
Desai, K.V.; Xiao, N.; Wang, W.; et al. Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proc Natl Acad Sci USA 2002, 99, 6967-6972.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6967-6972
-
-
Desai, K.V.1
Xiao, N.2
Wang, W.3
-
6
-
-
0344441000
-
Diagnostic and prognostic prediction using gene expression profiles in high dimensional microarray data
-
Simon, R. Diagnostic and prognostic prediction using gene expression profiles in high dimensional microarray data. Br J Cancer 2003, 89, 1599-1604.
-
(2003)
Br J Cancer
, vol.89
, pp. 1599-1604
-
-
Simon, R.1
-
7
-
-
21444445077
-
Development and validation of therapeutically relevant multi-gene biomarker classifiers
-
Simon, R. Development and validation of therapeutically relevant multi-gene biomarker classifiers. J Natl Cancer Inst 2005, 97, 866-867.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 866-867
-
-
Simon, R.1
-
8
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer, L,J.; Dai, H.; Vijver MJvd.; et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002, 415, 530-536.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van't Veer, L.J.1
Dai, H.2
MJvd, V.3
-
9
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
Vijver, M.J.v.D.; He, Y.D.; Veer, L.J.v.t.; et al. A gene-expression signature as a predictor of survival in breast cancer. New Engl J Med 2002, 347(25), 1999-2009.
-
(2002)
New Engl J Med
, vol.347
, Issue.25
, pp. 1999-2009
-
-
Vijver, M.J.V.D.1
He, Y.D.2
Veer, L.J.V.T.3
-
10
-
-
2942578063
-
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
-
Ma, X.J.; Wang, Z.; Ryan, P.D.; et al. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 2004, 5, 1-10.
-
(2004)
Cancer Cell
, vol.5
, pp. 1-10
-
-
Ma, X.J.1
Wang, Z.2
Ryan, P.D.3
-
11
-
-
2942729848
-
Gene expression profiles predict complete patholo gic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer
-
Ayers, M.; Symmans, W.F.; Stec, J.; et al. Gene expression profiles predict complete patholo gic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer. J Clin Oncol 2005, 22(12), 2284-2293.
-
(2005)
J Clin Oncol
, vol.22
, Issue.12
, pp. 2284-2293
-
-
Ayers, M.1
Symmans, W.F.2
Stec, J.3
-
12
-
-
20044377912
-
Molecular classification of Tamoxifen-resistant breast carcinomas by gene expression profiling
-
Jansen, M.P.H.M.; Foekens, J.A.; Staveren, I.L.v.; et al. Molecular classification of Tamoxifen-resistant breast carcinomas by gene expression profiling. J Clin Oncol 2005, 23(4), 732-740.
-
(2005)
J Clin Oncol
, vol.23
, Issue.4
, pp. 732-740
-
-
Jansen, M.P.H.M.1
Foekens, J.A.2
Staveren, I.L.V.3
-
13
-
-
0034680102
-
Molecular portraits of human breast tumors
-
Perou, C.M.; Sorlie, T.; Eisen, M.B.; et al. Molecular portraits of human breast tumors. Nature 2000, 406, 747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
14
-
-
0037245343
-
Pitfalls in the analysis of DNA microarray data: Class prediction methods
-
Simon, R.; Radmacher, M.D.; Dobbin, K.; McShane, L.M. Pitfalls in the analysis of DNA microarray data: class prediction methods. J Natl Cancer Inst 2003, 95, 14-18.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 14-18
-
-
Simon, R.1
Radmacher, M.D.2
Dobbin, K.3
McShane, L.M.4
-
15
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y.; Hochberg, Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Stat Soc Ser B 1995, 57, 289-300.
-
(1995)
J Roy Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
16
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher, V.G.; Tibshirani, R.; Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci 2001, 98, 5116-5121.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
17
-
-
42649139273
-
-
Simon, R.; Lam, A.P. BRB-ArrayTools Users Guide (Version 34). Bethesda, MD: Biometric Research Branch National Cancer Institute, 2005. Technical Report 46, hhtp://linus.nci. nih.gov./brb.
-
Simon, R.; Lam, A.P. BRB-ArrayTools Users Guide (Version 34). Bethesda, MD: Biometric Research Branch National Cancer Institute, 2005. Technical Report 46, hhtp://linus.nci. nih.gov./brb.
-
-
-
-
18
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A.; Tamayo, P.; Mootha, V.K. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005, 102 (43), 15545-15550.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
19
-
-
26444608611
-
Discovering statisti cally significant pathways in expression profiling studies
-
Tian, L.; Greenberg, S.A.; Kong, S.W.; Altschuler, J.; Kohane, I.S.; Park, P.J. Discovering statisti cally significant pathways in expression profiling studies. Proc Natl Acad Sci USA 2005, 102 (38), 13544-13549.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.38
, pp. 13544-13549
-
-
Tian, L.1
Greenberg, S.A.2
Kong, S.W.3
Altschuler, J.4
Kohane, I.S.5
Park, P.J.6
-
20
-
-
0035991757
-
A paradigm for class prediction using gene expression profiles
-
Radmacher, M.D.; McShane, L.M.; Simon, R. A paradigm for class prediction using gene expression profiles. J Comput Biol 2002, 9, 505-511.
-
(2002)
J Comput Biol
, vol.9
, pp. 505-511
-
-
Radmacher, M.D.1
McShane, L.M.2
Simon, R.3
-
21
-
-
3342964832
-
Classification in microarray experiments
-
Speed T, ed, New York: Chapman & Hall/CRC
-
Dudoit, S.; Fridlyand, J. Classification in microarray experiments. In: Speed T, ed. Statisti cal Analysis of Gene Expression Microarray Data. New York: Chapman & Hall/CRC, 2003, 93-158.
-
(2003)
Statisti cal Analysis of Gene Expression Microarray Data
, pp. 93-158
-
-
Dudoit, S.1
Fridlyand, J.2
-
22
-
-
0037142053
-
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
-
Rosenwald, A.; Wright, G.; Chan, W.C.; et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. New Engl J Med 2002, 346, 1937-1947.
-
(2002)
New Engl J Med
, vol.346
, pp. 1937-1947
-
-
Rosenwald, A.1
Wright, G.2
Chan, W.C.3
-
23
-
-
13444249852
-
Prediction of cancer outcome with microarrays: A multiple random validation strategy
-
Michiels, S.; Koscielny, S.; Hill, C. Prediction of cancer outcome with microarrays: a multiple random validation strategy. Lancet 2005, 365, 488-492.
-
(2005)
Lancet
, vol.365
, pp. 488-492
-
-
Michiels, S.1
Koscielny, S.2
Hill, C.3
-
24
-
-
25144494760
-
Prediction error estimation: A comparison of resampling methods
-
Molinaro, A.M.; Simon, R.; Pfeiffer, R.M. Prediction error estimation: a comparison of resampling methods. Bioinformatics 2005, 21 (15), 3301-3307.
-
(2005)
Bioinformatics
, vol.21
, Issue.15
, pp. 3301-3307
-
-
Molinaro, A.M.1
Simon, R.2
Pfeiffer, R.M.3
-
25
-
-
18944384502
-
When is a genomic classifier ready for prime time? Nat Clin Pract
-
Simon, R. When is a genomic classifier ready for prime time? Nat Clin Pract Oncol 2004, 1 (1), 2-3.
-
(2004)
Oncol
, vol.1
, Issue.1
, pp. 2-3
-
-
Simon, R.1
-
26
-
-
33644688970
-
A roadmap for developing and validating therapeutically relevant genomic classifiers
-
Simon, R. A roadmap for developing and validating therapeutically relevant genomic classifiers. J Clin Oncol 2005, 23, 7332-7341.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7332-7341
-
-
Simon, R.1
-
27
-
-
19944429996
-
Inter-laboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays
-
Dobbin, K.; Beer, D.G.; Meyerson, M.; et al. Inter-laboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res 2005, 11, 565-572.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 565-572
-
-
Dobbin, K.1
Beer, D.G.2
Meyerson, M.3
-
28
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik, S.; Shak, S.; Tang, G.; et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. New Engl J Med 2004, 351, 2817-2826.
-
(2004)
New Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
-
29
-
-
0028318390
-
Statistical aspects of prognostic factor studies in oncology
-
Simon, R.; Altaian, D.G. Statistical aspects of prognostic factor studies in oncology. Br J Cancer 1994, 69, 979-985.
-
(1994)
Br J Cancer
, vol.69
, pp. 979-985
-
-
Simon, R.1
Altaian, D.G.2
-
30
-
-
0035868668
-
update of recommendations for the use of tumor markers in breast and colorectal cancer: Clinical practice guidelines of the American Society of Clinical Oncology
-
Bast, R.C.; Ravdin, P.; Hayes, D.P.; et al. 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001, 19, 1865-1878.
-
(2000)
J Clin Oncol
, vol.2001
, Issue.19
, pp. 1865-1878
-
-
Bast, R.C.1
Ravdin, P.2
Hayes, D.P.3
-
31
-
-
6044278144
-
-
Simon, R.; Maitournam, A. Evaluating the efficiency of targeted designs for randomized clinical trials. Clin Cancer Res 2004, 10, 6759-6763, supplement and correction 2006, 12, 3229.
-
Simon, R.; Maitournam, A. Evaluating the efficiency of targeted designs for randomized clinical trials. Clin Cancer Res 2004, 10, 6759-6763, supplement and correction 2006, 12, 3229.
-
-
-
-
32
-
-
13644270099
-
On the efficiency of targeted clinical trials
-
Maitournam, A.; Simon, R. On the efficiency of targeted clinical trials. Stat Med 2005, 24, 329-339.
-
(2005)
Stat Med
, vol.24
, pp. 329-339
-
-
Maitournam, A.1
Simon, R.2
-
33
-
-
33646047815
-
Use of genomic signatures in therapeutics development
-
Simon, R.; Wang, S.J. Use of genomic signatures in therapeutics development. Pharmacogenomics J 2006, 6, 166-173.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 166-173
-
-
Simon, R.1
Wang, S.J.2
-
34
-
-
27744537954
-
Adaptive signature design: An adaptive clinical trial design for generating and prospectively testing a gene expression signature for sensitive patients
-
Freidlin, B.; Simon, R. Adaptive signature design: an adaptive clinical trial design for generating and prospectively testing a gene expression signature for sensitive patients. Clin Cancer Res 2005, 11, 7872-7878.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7872-7878
-
-
Freidlin, B.1
Simon, R.2
-
35
-
-
77953594683
-
Guidelines for the design of clinical studies for development and validation of therapeutically relevant biomarkers and biomarker based classification systems
-
Hayes DP, Gasparini G, eds, New York: Humana Press
-
Simon, R. Guidelines for the design of clinical studies for development and validation of therapeutically relevant biomarkers and biomarker based classification systems. In: Hayes DP, Gasparini G, eds. Biomarkers in Breast Cancer: Molecular Diagnostics for Predictingand Monitoring Therapeutic Effect. New York: Humana Press, 2005, 3-16.
-
(2005)
Biomarkers in Breast Cancer: Molecular Diagnostics for Predictingand Monitoring Therapeutic Effect
, pp. 3-16
-
-
Simon, R.1
-
36
-
-
15744374441
-
Clinical trial designs for predictive marker validation in cancer treatment trials
-
Sargent, D.J.; Conley, B.A.; Allegra, C.; Collette, L. Clinical trial designs for predictive marker validation in cancer treatment trials. J Clin Oncol 2005, 23 (9), 2020-2027.
-
(2005)
J Clin Oncol
, vol.23
, Issue.9
, pp. 2020-2027
-
-
Sargent, D.J.1
Conley, B.A.2
Allegra, C.3
Collette, L.4
-
37
-
-
10944260135
-
Clinical trial design for microarray predictive marker discovery and assessment
-
Pusztai, L.; Hess, K.R. Clinical trial design for microarray predictive marker discovery and assessment. Ann Oncol 2004, 15, 1731-1737.
-
(2004)
Ann Oncol
, vol.15
, pp. 1731-1737
-
-
Pusztai, L.1
Hess, K.R.2
|