High Amplitude T-wave Alternans Precedes Spontaneous Ventricular Tachycardia or Fibrillation in ICD Electrograms

Heart Rhythm

Volumn 5, Issue 5, 2008, Pages 670-676

  Swerdlow, Charles D ^a   Zhou, Xiaohong ^a   Voroshilovsky, Olga ^a   Abeyratne, Athula ^a   Gillberg, Jeff ^a  

^a MEDTRONIC INC   (United States)

Author keywords

Implantable cardioverter defibrillator; T wave alternans; Tachyarrhythmias

Indexed keywords

ADULT; AGED; ARTICLE; AVERAGING; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DEFIBRILLATION; DEFIBRILLATOR; ELECTROCARDIOGRAM; FEASIBILITY STUDY; HEART ATRIUM PACING; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; MALE; PRIORITY JOURNAL; SIGNAL PROCESSING; SIMULATION; SINUS RHYTHM; T WAVE AMPLITUDE; VALIDATION PROCESS;

AGED; AGED, 80 AND OVER; DEFIBRILLATORS, IMPLANTABLE; ELECTROCARDIOGRAPHY; FEASIBILITY STUDIES; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; MALE; MIDDLE AGED; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION;

EID: 42649083305     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2008.02.018     Document Type: Article

References (19)

1. Pastore J.M., Girouard S.D., Laurita K.R., et al. Mechanism linking T-wave alternans to the genesis of cardiac fibrillation. Circulation 99 (Mar 16 1999) 1385-1394
2. Rosenbaum D.S., Jackson L.E., Smith J.M., et al. Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med 330 (Jan 27 1994) 235-241
3. Bloomfield D.M., Steinman R.C., Namerow P.B., et al. Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum. Circulation 110 (Oct 5 2004) 1885-1889
4. Narayan S.M. T-wave alternans and the susceptibility to ventricular arrhythmias. J Am Coll Cardiol 47 (Jan 17 2006) 269-281
5. Shusterman V., Goldberg A., and London B. Upsurge in T-wave alternans and nonalternating repolarization instability precedes spontaneous initiation of ventricular tachyarrhythmias in humans. Circulation 113 (Jun 27 2006) 2880-2887
6. Armoundas A.A., Nanke T., and Cohen R.J. Images in cardiovascular medicine. T-wave alternans preceding torsade de pointes ventricular tachycardia. Circulation 101 (May 30 2000) 2550
7. Raeder E.A., Rosenbaum D.S., Bhasin R., et al. Alternating morphology of the QRST complex preceding sudden death. N Engl J Med 326 (Jan 23 1992) 271-272
8. Paz O., Zhou X., Gillberg J., et al. Detection of T-wave alternans using an implantable cardioverter-defibrillator. Heart Rhythm 3 (Jul 2006) 791-797
9. Armoundas A.A., Albert C.M., Cohen R.J., et al. Utility of implantable cardioverter defibrillator electrograms to estimate repolarization alternans preceding a tachyarrhythmic event. J Cardiovasc Electrophysiol 15 (May 2004) 594-597
10. Christini D.J., Stein K.M., Hao S.C., et al. Endocardial detection of repolarization alternans. IEEE Trans Biomed Eng 50 (Jul 2003) 855-862
11. Tsai J., Cao J.M., Zhou S., et al. T wave alternans as a predictor of spontaneous ventricular tachycardia in a canine model of sudden cardiac death. J Cardiovasc Electrophysiol 13 (Jan 2002) 51-55
12. Maybhate A., Hao S.C., Iwai S., et al. Detection of repolarization alternans with an implantable cardioverter defibrillator lead in a porcine model. IEEE Trans Biomed Eng 52 (Jul 2005) 1188-1194
13. Bloomfield D.M., Hohnloser S.H., and Cohen R.J. Interpretation and classification of microvolt T wave alternans tests. J Cardiovasc Electrophysiol 13 (May 2002) 502-512
14. Nearing B.D., and Verrier R.L. Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy. J Appl Physiol 92 (Feb 2002) 541-549
15. Sörnmo L., and Laguna P. Bioelectrical Signal Processing in Cardiac and Neurological Applications (2005), Elsevier Academic Press, Burlington, MA and San Diego, CA
16. Karma A. Electrical alternans and spiral wave breakup in cardiac tissue. Chaos 4 (Sep 1994) 461-472
17. Adam D., Powell A., Gordon H., et al. Ventricular fibrillation and fluctuations in the magnitude of the repolarization vector. IEEE Comput Cardiol (1982) 241-244
18. Smith J.M., Clancy E.A., Valeri C.R., et al. Electrical alternans and cardiac electrical instability. Circulation 77 (Jan 1988) 110-121
19. Narayan S.M., Smith J.M., Schechtman K.B., et al. T-wave alternans phase following ventricular extrasystoles predicts arrhythmia-free survival. Heart Rhythm 2 (Mar 2005) 234-241