T-wave alternans phase following ventricular extrasystoles predicts arrhythmia-free survival

Heart Rhythm

Volumn 2, Issue 3, 2005, Pages 234-241

  Narayan, Sanjiv M ^a   Smith, Joseph M ^b   Schechtman, Kenneth B ^b   Lindsay, Bruce D ^b   Cain, Michael E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electrophysiologic study; Sudden death; T wave alternans; Ventricular extrasystoles; Ventricular tachyarrhythmias

Indexed keywords

ADULT; AGE; AGED; ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART ARRHYTHMIA; HEART EJECTION FRACTION; HEART ELECTROPHYSIOLOGY; HEART LEFT VENTRICLE FAILURE; HEART REPOLARIZATION; HEART STIMULATION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE PACING; HEART VENTRICLE TACHYCARDIA; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SUDDEN DEATH; SURVIVAL RATE; T WAVE;

AGED; ALGORITHMS; ARRHYTHMIA; CARDIAC COMPLEXES, PREMATURE; CARDIAC PACING, ARTIFICIAL; DISEASE-FREE SURVIVAL; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; SURVIVAL ANALYSIS;

EID: 14644416568     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2004.12.010     Document Type: Article

References (37)

1. A.J. Moss W. Zareba W.J. Hall H. Klein D.J. Wilber D.S. Cannom J.P. Daubert S.L. Higgins M.W. Brown M.L. Andrews the Multicenter Automatic Defibrillator Implantation Trial II Investigators Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction N Engl J Med 346 2002 877-883
2. A.E. Buxton K.L. Lee G.E. Hafley D.G. Wyse J.D. Fisher M.H. Lehmann L.A. Pires M.R. Gold D.L. Packer M.E. Josephson E.N. Prystowsky M.R. Talajic the MUSTT Investigators Relation of ejection fraction and inducible ventricular tachycardia to mode of death in patients with coronary artery disease: An analysis of patients enrolled in the Multicenter Unsustained Tachycardia Trial Circulation 106 2002 2466-2472
3. A.E. Buxton K.L. Lee L.D. Carlo M.R. Gold G.S. Greer E.N. Prystowsky M.F. O'Toole A. Tang J.D. Fisher J. Coromilas M. Talajic G. Hafley Multicenter Unsustained Tachycardia Trial Investigators (MUSTT) Electrophysiologic testing to identify patients with coronary artery disease who are at risk for sudden death N Engl J Med 342 2000 1937-1945
4. A. Moss J. Daubert W. Zareba MADIT-II: Clinical implications Card Electrophysiol Rev 6 2002 463-465
5. A.P. Maggioni G. Zuanetti M.G. Franzosi F. Rovelli E. Santoro L. Staszewsky L. Tavazzi G. Tognoni Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the fibrinolytic era. GISSI-2 results Circulation 87 1993 312-322
6. S.M. Al-Khatib A.L. Stebbins R.M. Califf K.L. Lee C.B. Granger H.D. White P.W. Armstrong E.J. Topol E.M. Ohman Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: Results from the GUSTO-III trial Am Heart J 145 2003 515-521
7. G. Schmidt M. Malik P. Barthel R. Schneider K. Ulm L. Rolnitzky A.J. Camm J.T. Bigger Jr A. Schömig Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction Lancet 353 1999 1390-1396
8. C.-S. Kuo K. Munakata C.P. Reddy B. Surawicz Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion of action potential durations Circulation 67 1983 1356-1367
9. K.R. Laurita S.D. Girouard D.S. Rosenbaum Modulation of ventricular repolarization by a premature stimulus: Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart Circ Res 79 1996 493-503
10. K.R. Laurita D.S. Rosenbaum Interdependence of modulated dispersion and tissue structure in the mechanism of unidirectional block Circ Res 87 2000 922-928
11. B.D. Nearing A.H. Huang R.L. Verrier Dynamic tracking of cardiac vulnerability by complex demodulation of the T-wave Science 252 1991 437-440
12. M.R. Gold D.M. Bloomfield K.P. Anderson N. El-Sherif D.J. Wilber W.J. Groh N.A.M. Estes E.S. Kaufman M.L. Greenberg D.S. Rosenbaum A comparison of T wave alternans, signal averaged electrocardiography and programmed ventricular stimulation for arrhythmia risk stratification J Am Coll Cardiol 36 2000 2247-2253
13. S.M. Narayan B.D. Lindsay J.M. Smith Demonstrating the pro-arrhythmic preconditioning of single premature extrastimuli using the magnitude, phase and temporal distribution of repolarization alternans Circulation 100 1999 1887-1893
14. L.A. Pires M.H. Lehmann A.E. Buxton G.E. Hafley K.L. Lee Differences in inducibility and prognosis of in-hospital versus out-of-hospital identified nonsustained ventricular tachycardia in patients with coronary artery disease: Clinical and trial design implications J Am Coll Cardiol 38 2001 1156-1162
15. S.M. Narayan J.M. Smith Spectral analysis of periodic fluctuations in ECG repolarization IEEE Trans Biomed Eng 46 1999 203-212
16. S.M. Narayan J.M. Smith Exploiting rate hysteresis in repolarization alternans to optimize the sensitivity and specificity for ventricular tachycardia J Am Coll Cardiol 35 2000 1485-1492
17. J.M. Smith E. Clancy C. Valeri J. Ruskin R. Cohen Electrical alternans and cardiac electrical instability Circulation 77 1988 110-121
18. D.M. Bloomfield S.H. Hohnloser R.J. Cohen Interpretation and classification of microvolt T-wave alternans tests J Cardiovasc Electrophysiol 13 2002 502-512
19. A.F. Osman E.J. Rashba S.R. Shorovsky M.R. Gold Prognostic value of voltage magnitude during T-wave alternans (TWA) assessment with exercise and pacing in patients with ischemic cardiomyopathy Pacing Clin Electrophysiol 24 2001 530
20. K. Tanno S. Ryu N. Watanabe Y. Minoura M. Kawamura T. Asano Y. Kobayashi T. Katagiri Microvolt T-wave alternans as a predictor of ventricular tachyarrhythmias: A prospective study using atrial pacing Circulation 109 2004 1854-1858
21. D.M. Bloomfield R.C. Steinman P.B. Namerow M. Parides J. Davidenko E.S. Kaufman T. Shinn A. Curtis J. Fontaine D. Holmes A. Russo C. Tang J.T. Bigger Jr Microvolt T.-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: A solution to the multicenter Automatic Defibrillator Implantation Trial (MADIT) II Conundrum Circulation 110 2004 1885-1889
22. I. Cygankiewicz J. Wranicz H. Bolinska J. Zaslonka W. Zareba Relationship between heart rate turbulence and heart rate, heart rate variability, and number of ventricular premature beats in coronary patients J Cardiovasc Electrophysiol 15 2004 731-773
23. T.G. Farrell Y. Bashir T. Cripps M. Malik J. Poloniecki E.D. Bennett D.E. Ward A.J. Camm Risk stratification for arrhythmic events in postinfarction patients based on heart rate variability, ambulatory electrocardiographic variables and the signal-averaged electrocardiogram J Am Coll Cardiol 18 1991 687-697
24. H. Hashimoto M. Asano M. Nakashima Potentiating effects of a ventricular premature beat on the alternation of the ST-T complex of epicardial electrograms and the incidence of ventricular arrhythmias during acute coronary occlusion in dogs J Electrocardiol 17 1984 289-301
25. T. Konta K. Ikeda M. Yamaki K. Nakamura K. Honma I. Kubota S. Yasui Significance of discordant ST alternans in ventricular fibrillation Circulation 82 1990 2185-2189
26. J.M. Pastore S.D. Girouard K.R. Laurita F.G. Akar D.S. Rosenbaum Mechanism linking T-wave alternans to the genesis of cardiac fibrillation Circulation 99 1999 1385-1394
27. D.S. Rubenstein S.L. Lipsius Premature beats elicit a phase reversal of mechanoelectrical alternans in cat ventricular myocytes: A possible mechanism for reentrant arrhythmias Circulation 91 1995 201-214
28. H. Hashimoto K. Suzuki M. Nakashima Effects of the ventricular premature beat on the alternation of the repolarization phase in ischemic myocardium during acute coronary occlusion in dogs J Electrocardiol 17 1984 229-238
29. B. Nearing R. Verrier Tracking cardiac electrical instability by computing interlead heterogeneity of T-wave morphology J Appl Physiol 95 2003 2265-2272
30. E.J. Rashba A.F. Osman K. MacMurdy M.M. Kirk S.E. Sarang R.W. Peters S.R. Shorofsky M.R. Gold Enhanced detection of arrhythmia vulnerability using T wave alternans, left ventricular ejection fraction, and programmed ventricular stimulation: A prospective study in subjects with chronic ischemic heart disease J Cardiovasc Electrophysiol 15 2004 170-176
31. E.J. Rashba A.F. Osman K. MacMurdy M.M. Kirk S. Sarang R.W. Peters S.R. Shorofsky M.R. Gold Influence of QRS duration on the prognostic value of T wave alternans J Cardiovasc Electrophysiol 13 2002 770-775
32. U. Srivatsa A. Iwasa B. Berman R. Hoppe T. Oliver S. Narayan T-wave alternans during cardiac resynchronization therapy is greater in the presence of elevated levels of B-type natriuretic peptide Heart Rhythm 1 2004 S128-S129
33. A.A. Armoundas D.S. Rosenbaum J.N. Ruskin H. Garan R.J. Cohen Prognostic significance of electrical alternans versus signal averaged electrocardiography in predicting the outcome of electrophysiologic testing and arrhythmia-free survival Heart 80 1998 251-256
34. P.J. Zimetbaum A.E. Buxton W. Batsford J.D. Fisher G.E. Hafley K.L. Lee M.F. O'Toole R.L. Page M. Reynolds M.E. Josephson Electrocardiographic predictors of arrhythmic death and total mortality in the Multicenter Unsustained Tachycardia Trial Circulation 110 2004 766-769
35. M.L. Walker X. Wan G.E. Kirsch D.S. Rosenbaum Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans Circulation 108 2003 2704-2709
36. B.D. Nearing R.L. Verrier Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy J Appl Physiol 92 2002 541-549
37. W.J. Kop D.S. Krantz B.D. Nearing J.S. Gottdiener J.F. Quigley M. O'Callahan A.A. DelNegro T.D. Friehling P. Karasik S. Suchday J. Levine R.L. Verrier Effects of acute mental stress and exercise on T-wave alternans in patients with implantable cardioverter defibrillators and controls Circulation 109 2004 1864-1869