Disruption of Pichia pastoris PMRI gene decreases its folding capacity on human serum albumin and interferon-α2b fusion protein

Yeast

Volumn 25, Issue 4, 2008, Pages 279-286

  Zhao, Hong Liang ^a   Xue, Chong ^a   Wang, Yang ^a   Duan, Qing Fen ^a   Xiong, Xiang Hua ^a   Yao, Xue Qin ^a   Liu, Zhi Min ^a  

^a BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

Author keywords

Folding capacity; HSA fusion protein; Pichia pastoris; PpPMR1

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ALPHA2B INTERFERON; AMINO ACID; CALCIUM CHANNEL P TYPE; CYSTEINE; HUMAN SERUM ALBUMIN; HYBRID PROTEIN; PROTEIN PMR1; UNCLASSIFIED DRUG;

ALKALINITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; GENE DISRUPTION; GENETIC HETEROGENEITY; NONHUMAN; PICHIA PASTORIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REPORTER GENE; SITE DIRECTED MUTAGENESIS;

ANTIVIRAL AGENTS; CALCIUM-TRANSPORTING ATPASES; CELL LINE; CLONING, MOLECULAR; CYTOPATHOGENIC EFFECT, VIRAL; FUNGAL PROTEINS; GENES, REPORTER; HUMANS; HYDROGEN-ION CONCENTRATION; INTERFERON ALFA-2B; MUTAGENESIS, SITE-DIRECTED; PICHIA; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SERUM ALBUMIN; VESICULOVIRUS;

PICHIA PASTORIS;

EID: 42549143546     PISSN: 0749503X     EISSN: 10970061     Source Type: Journal    
DOI: 10.1002/yea.1589     Document Type: Article

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