Hypertension increases middle cerebral artery resting tone in spontaneously hypertensive rats: Role of tonic vasoactive factor availability

Clinical Science

Volumn 114, Issue 9-10, 2008, Pages 651-659

  González, José M ^a   Somoza, Beatriz ^a   Conde, M Victoria ^a   Fernández Alfonso, Maria S ^b   González, M Carmen ^a   Arribas, Silvia M ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Mesenteric resistance artery; Middle cerebral artery; Nitric oxide; Spontaneously hypertensive rat; Stroke; Superoxide anion

Indexed keywords

LUCIGENIN; NITRIC OXIDE; NITROPRUSSIDE SODIUM; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY TONE; ARTICLE; CHEMOLUMINESCENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE; HYPERTENSION; MALE; MESENTERIC ARTERY; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASODILATATION; WISTAR KYOTO RAT;

ANIMALS; BIOLOGICAL MARKERS; CHEMILUMINESCENT MEASUREMENTS; HYPERTENSION; MALE; MICROSCOPY, CONFOCAL; MIDDLE CEREBRAL ARTERY; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPEROXIDES;

EID: 42549131385     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20070361     Document Type: Article

References (50)

1. Faraci, F. M. and Heistad, D. D. (1990) Regulation of large cerebral arteries and cerebral microvascular pressure. Circ. Res. 66, 8-17
2. Brian, Jr, J. E., Faraci, F. M. and Heistad, D. D. (1996) Recent insights into the regulation of cerebral circulation. Clin. Exp. Pharmacol. Physiol. 23, 449-457
3. Faraci, F. M. and Brian, Jr, J. E. (1994) Nitric oxide and the cerebral circulation. Stroke 25, 692-703
4. Andresen, J., Shafi, N. I. and Bryan, Jr, R. M. (2006) Endothelial influences on cerebrovascular tone. J. Appl. Physiol. 100, 318-327
5. Mulvany, M. J. (2002) Small artery remodeling in hypertension. Curr. Hypertens. Rep. 4, 49-55
6. Schiffrin, E. L. and Touyz, R. M. (2004) From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. Am. J. Physiol. Heart Circ. Physiol. 287, H435-H446
7. Arribas, S. M., Gordon, J. F., Daly, C. J., Dominiczak, A. F. and McGrath, J. C. (1996) Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke 27, 1118-1122
8. Arribas, S. M., Gonzalez, C., Graham, D., Dominiczak, A. F. and McGrath, J. C. (1997) Cellular changes induced by chronic nitric oxide inhibition in intact rat basilar arteries revealed by confocal microscopy. J. Hypertens. 15, 1685-1693
9. Shinyama, H., Nagai, H., Kawamura, T., Narita, Y., Nakamura, N. and Kagitani, Y. (1997) Effects of long-term treatment with the calcium antagonist AE0047 on cerebrovascular autoregulation and hypertrophy in spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 30, 616-622
10. Dunn, W. R., Wallis, S. J. and Gardiner, S. M. (1998) Remodelling and enhanced myogenic tone in cerebral resistance arteries isolated from genetically hypertensive brattleboro rats. J. Vasc. Res. 35, 18-26
11. Izzard, A. S., Graham, D., Burnham, M. P., Heerkens, E. H., Dominiczak, A. F. and Heagerty, A. M. (2003) Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat. Am. J. Physiol. Heart Circ. Physiol. 285, H1489-H1494
12. Izzard, A. S., Horton, S., Heerkens, E. H., Shaw, L. and Heagerty, A. M. (2006) Middle cerebral artery structure and distensibility during developing and established phases of hypertension in the spontaneously hypertensive rat. J. Hypertens. 24, 875-880
13. Bund, S. J. and Lee, R. M. (2003) Arterial structural changes in hypertension: a consideration of methodology, terminology and functional consequence. J. Vasc. Res. 40, 547-557
14. Gonzalez, J. M., Briones, A. M., Somoza, B. et al. (2006) Postnatal alterations in elastic fiber organization precede resistance artery narrowing in SHR. Am. J. Physiol. Heart Circ. Physiol. 291, H804-H812
15. Wu, R., Millette, E., Wu, L. and de Champlain, J. (2001) Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats. J. Hypertens. 19, 741-748
16. Touyz, R. M. (2004) Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: What is the clinical significance? Hypertension 44, 248-252
17. Kerr, S., Brosnan, M. J., McIntyre, M., Reid, J. L., Dominiczak, A. F. and Hamilton, C. A. (1999) Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 33, 1353-1358
18. Ulker, S., McMaster, D., McKeown, P. P. and Bayraktutan, U. (2003) Impaired activities of antioxidant enzymes elicit endothelial dysfunction in spontaneous hypertensive rats despite enhanced vascular nitric oxide generation. Cardiovasc. Res. 59, 488-500
19. Suzuki, H., Swei, A., Zweifach, B. W. and Schmid-Schonbein, G. W. (1995) In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography. Hypertension 25, 1083-1089
20. Briones, A. M., Gonzalez, J. M., Somoza, B. et al. (2003) Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. J. Physiol. 552, 185-195
21. Arribas, S. M., Daly, C. J., Gonzalez, M. C. and McGrath, J. C. (2007) Imaging the vascular wall using confocal microscopy. J. Physiol. 584, 5-9
22. Didion, S. P. and Faraci, F. M. (2002) Effects of NADH and NADPH on superoxide levels and cerebral vascular tone. Am. J. Physiol. Heart Circ. Physiol. 282, H688-H695
23. Smeda, J. S., Lombard, J. H., Madden, J. A. and Harder, D. R. (1987) The effect of alkaline pH and transmural pressure on arterial constriction and membrane potential of hypertensive cerebral arteries. Pflugers Arch. 408, 239-242
24. Dickhout, J. G. and Lee, R. M. (1998) Blood pressure and heart rate development in young spontaneously hypertensive rats. Am. J. Physiol. 274, H794-H800
25. Van Gorp, A. W., Schenau, D. S., Hoeks, A. P., Boudier, H. A., de Mey, J. G. and Reneman, R. S. (2000) In spontaneously hypertensive rats alterations in aortic wall properties precede development of hypertension. Am. J. Physiol. Heart Circ. Physiol. 278, H1241-H1247
26. Gonzalez, C., Fernandez, A., Martin, C., Moncada, S. and Estrada, C. (1992) Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock. Biochem. Biophys. Res. Commun. 186, 150-156
27. Ackermann, A., Fernández-Alfonso, M. S., Sánchez de Rojas, R., Ortega, T., Paul, M. and González, C. (1998) Modulation of angiotensin-converting enzyme by nitric oxide. Br. J. Pharmacol. 124, 291-298
28. Hernanz, R., Briones, A. M., Alonso, M. J., Vila, E. and Salaices, M. (2004) Hypertension alters role of iNOS, COX-2, and oxidative stress in bradykinin relaxation impairment after LPS in rat cerebral arteries. Am. J. Physiol. Heart Circ. Physiol. 287, H225-H234
29. Furfine, E. S., Harmon, M. F., Paita, J. E. et al. (1994) Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline. J. Biol. Chem. 269, 26677-26683
30. Patterson, M. E., Mullins, J. J. and Mitchell, K. D. (2007) Renoprotective effects of neuronal NOS derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. Am. J. Physiol. Renal Physiol. 294, F205-F211
31. Lavi, S., Egbarya, R., Lavi, R. and Jacob, G. (2003) Role of nitric oxide in the regulation of cerebral blood flow in humans: chemoregulation versus mechanoregulation. Circulation 107, 1901-1905
32. Fouyas, I. P., Kelly, P. A., Ritchie, I. M. and Whittle, I. R. (1997) Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats. Br. J. Pharmacol. 121, 49-56
33. Bauersachs, J., Bouloumie, A., Mulsch, A., Wiemer, G., Fleming, I. and Busse, R. (1998) Vasodilator dysfunction in aged spontaneously hypertensive rats: changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production. Cardiovasc. Res. 37, 772-779
34. Lopez-Farre, A., Rodriguez-Feo, J. A., Garcia-Colis, E. et al. (2002) Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the α1-receptor blocker doxazosin. J. Hypertens. 20, 463-470
35. Ruetten, H., Zabel, U., Linz, W. and Schmidt, H. H. (1999) Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats. Circ. Res. 85, 534-541
36. Kojima, H., Nakatsubo, N., Kikuchi, K. et al. (1998) Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins. Anal. Chem. 70, 2446-2453
37. 2+ and NO in endothelium of coronary arteries. Am. J. Physiol. Heart Circ. Physiol. 283, H2725-H2732
38. Somoza, B., Gonzalez, M. C., Gonzalez, J. M., Abderrahim, F., Arribas, S. M. and Fernandez-Alfonso, M. S. (2005) Modulatory role of the adventitia on noradrenaline and angiotensin II responses role of endothelium and AT2 receptors. Cardiovasc. Res. 65, 478-486
39. Hamilton, C. (2002) Nitric oxide, oxidative stress and hypertension: a complex equation. J. Hypertens. 20, 1055-1056
40. Wu, R., Lamontagne, D. and de Champlain, J. (2002) Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats. Circulation 105, 387-392
41. Kawczynska-Drozdz, A., Olszanecki, R., Jawien, J. et al. (2006) Ghrelin inhibits vascular superoxide production in spontaneously hypertensive rats. Am. J. Hypertens. 19, 764-767
42. Alvarez de Sotomayor, M., Bueno, R., Pérez-Guerrero, C. and Herrera, M. D. (2007) Effect of L-carnitine and propionyl-L- carnitine on endothelial function of small mesenteric arteries from SHR. J. Vasc. Res. 44, 354-364
43. Paravicini, T. M., Chrissobolis, S., Drummond, G. R. and Sobey, C. G. (2004) Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke 35, 584-589
44. Miller, A. A., Drummond, G. R., Schmidt, H. H. and Sobey, C. G. (2005) NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries. Circ. Res. 97, 1055-1062
45. Wei, E. P., Kontos, H. A. and Beckman, J. S. (1996) Mechanisms of cerebral vasodilation by superoxide, hydrogen peroxide, and peroxynitrite. Am. J. Physiol. 271, H1262-H1266
46. Didion, S. P. and Faraci, F. M. (2002) Effects of NADH and NADPH on superoxide levels and cerebral vascular tone. Am. J. Physiol. Heart Circ. Physiol. 282, H688-H695
47. Lacza, Z., Puskar, M., Kis, B., Perciaccante, J. V., Miller, A. W. and Busija, D. W. (2002) Hydrogen peroxide acts as an EDHF in the piglet pial vasculature in response to bradykinin. Am. J. Physiol. Heart Circ. Physiol. 283, H406-H411
48. New, D. I., Chesser, A. M., Thuraisingham, R. C. and Yaqoob, M. M. (2003) Cerebral artery responses to pressure and flow in uremic hypertensive and spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 284, H1212-H1216
49. Smeda, J. S., VanVliet, B. N. and King, S. R. (1999) Stroke-prone spontaneously hypertensive rats lose their ability to auto-regulate cerebral blood flow prior to stroke. J. Hypertens. 17, 1697-1705
50. Miller, A. A., Drummond, G. R. and Sobey, C. G. (2006) Reactive oxygen species in the cerebral circulation: are they all bad? Antioxid. Redox Signaling 8, 1113-1120