The "Rosen Triad": Tubular carcinoma, lobular carcinoma in situ, and columnar cell lesions

Advances in Anatomic Pathology

Volumn 15, Issue 3, 2008, Pages 140-146

  Brandt, Suzanne M ^a   Young, Gloria Q ^a   Hoda, Syed A ^a,b  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Breast; Breast carcinoma; Columnar cell lesions; Lobular carcinoma in situ; Tubular carcinoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

BREAST CANCER; CANCER DIAGNOSIS; CANCER INVASION; CARCINOMA IN SITU; CELL TYPE; COLUMNAR CELL LESION; DATA ANALYSIS; EXPERIENCE; HUMAN; LOBULAR CARCINOMA IN SITU; PATHOLOGIST; PATHOLOGY; PRIORITY JOURNAL; REVIEW; ROSEN TRIAD; STATISTICAL SIGNIFICANCE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CARCINOMA, LOBULAR; FEMALE; HUMANS; HYPERPLASIA; MAMMARY GLANDS, HUMAN; MIDDLE AGED; NEOPLASMS, MULTIPLE PRIMARY;

EID: 42549121101     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e31816ff313     Document Type: Review

References (28)

1. Rosen PP. Columnar cell hyperplasia is associated with lobular carcinoma in situ and tubular carcinoma. Am J Surg Pathol. 1999;23:1561.
2. Goldstein NS, O'Malley BA. Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts: a lesion associated with tubular carcinoma. Am J Clin Pathol. 1997;107:561-566.
3. Fernandez-Aguilar S, Simon P, Buxant F, et al. Tubular carcinoma of the breast and associated intra-epithelial lesions: a comparative study with invasive low-grade ductal carcinomas. Virchows Arch. 2005;447:683-687.
4. Cabral AH, Recine M, Paramo JC, et al. Tubular carcinoma of the breast: an institutional experience and review of the literature. Breast J. 2003;9:298-301.
5. Green I, McCormick B, Cranor M, et al. A comparative study of pure tubular and tubulolobular carcinoma of the breast. Am J Surg Pathol. 1997;21:653-657.
6. Gopalan A, Hoda SA. Columnar cell hyperplasia and lobular carcinoma in situ coexisting in the same duct. Breast J. 2005;11:210.
7. Brogi E, Oyama T, Koerner FC. Atypical cystic lobules in patients with lobular neoplasia. Int J Surg Pathol. 2001;9:201-206.
8. Pinder SE, Provenzano E, Reis-Filho JS. Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management. Pathology. 2007;39:208-216.
9. Abdel-Fatah TM, Powe DG, Hodi Z, et al. High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am J Surg Pathol. 2007;31:417-426.
10. Sahoo S, Recant WM. Triad of columnar cell alteration, lobular carcinoma in situ and tubular carcinoma of the breast. Breast J. 2005;11:140-142.
11. Ellis IO, Schnitt SJ, Sastre-Garau X, et al. Invasive breast carcinoma. In: Tavassoli FA, Devilee P, eds. Tumours of the Breast. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: IARC Press; 2003:26-27.
12. Rosen PP. Rosen's Breast Pathology. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2001:215-218.
13. Rosen PP, Hoda SA. Breast Pathology: Diagnosis by Needle Core Biopsy. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2006:96-102.
14. Leikola J, Hekkila P, von Smitten K, et al. The prevalence of axillary lymph-node metastases in patients with pure tubular carcinoma of the breast and sentinel node biopsy. Eur J Surg Oncol. 2006;32:488-491.
15. Chuba PJ, Hamre MR, Yap J, et al. Bilateral risk for subsequent breast cancer after lobular carcinoma in situ: analysis of surveillance, epidemiology, and end results data. J Clin Oncol. 2005;23:5534-5541.
16. Fraser JL, Raza S, Chorny K, et al. Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifications. Am J Surg Pathol. 1998;22:1521-1527.
17. O'Malley FP, Mohsin SK, Badve S, et al. Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breast. Mod Pathol. 2006;19:172-179.
18. Schnitt SJ, Vincent-Salomon A. Columnar cell lesions of the breast. Adv Anat Pathol. 2003;10:113-124.
19. Schnitt SJ. Flat epithelial atypia-classification, pathologic features and clinical significance. Breast Cancer Res. 2003;5:263-268.
20. Tavassoli FA, Hoefler H, Rosai J, et al. Intraductal proliferative lesions. In: Tavassoli FA, Devilee P, eds. Tumours of the breast. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: IARC Press; 2003:63-73.
21. Leibl S, Regitnig P, Moinfar F. Flat epithelial atypia (DIN 1a, atypical columnar change): an underdiagnosed entity very frequently coexisting with lobular neoplasia. Histopathology. 2007;50:859-865.
22. Muir R. The evolution of carcinoma of the mamma. J Pathol Bacteriol. 1941;52:155-172.
23. Simpson PT, Gale T, Reis-Filho JS, et al. Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis. Am J Surg Pathol. 2005;29:734-746.
24. Azzopardi JG. Problems in Breast Pathology. Philadelphia: WB Saunders; 1979:193-202.
25. Allred DC, Mohsin SK, Fuqua SA. Histological and biological evolution of human premalignant breast disease. Endocr Relat Cancer. 2001;8:47-61.
26. Waldman FM, Hwang ES, Etzell J, et al. Genomic alterations in tubular breast carcinomas. Hum Pathol. 2001;32:222-226.
27. Moinfar F, Man YG, Bratthauer GL, et al. Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type ("clinging ductal carcinoma in situ"): a simulator of normal mammary epithelium. Cancer. 2000;88:2072-2081.
28. Man S, Ellis IO, Sibbering M, et al. High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast carcinoma. Cancer Res. 1996;56:5484-5489.