메뉴 건너뛰기




Volumn 46, Issue 5, 2008, Pages 461-467

Small artery remodelling in hypertension: Causes, consequences and therapeutic implications

Author keywords

Cardiovascular risk; Essential hypertension; Inward eutrophic remodelling; Outward remodelling; Prognosis; Resistance vasculature; Small artery; Tissue transglutaminase; Vascular tone; Vasodilator therapy

Indexed keywords

BIOMEDICAL ENGINEERING; BLOOD; BLOOD VESSELS; PATHOLOGY; TISSUE;

EID: 42549104688     PISSN: 01400118     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11517-008-0305-3     Document Type: Article
Times cited : (62)

References (60)
  • 1
    • 0023239235 scopus 로고
    • Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation-contraction coupling in isolated resistance vessels from essential hypertensives
    • Aalkjaer C, Heagerty AM, Petersen KK, Swales JD, Mulvany MJ (1987) Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation-contraction coupling in isolated resistance vessels from essential hypertensives. Circ Res 61:181-186
    • (1987) Circ Res , vol.61 , pp. 181-186
    • Aalkjaer, C.1    Heagerty, A.M.2    Petersen, K.K.3    Swales, J.D.4    Mulvany, M.J.5
  • 2
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). JAMA 288(23):2981-2997
    • (2002) JAMA , vol.288 , Issue.23 , pp. 2981-2997
  • 5
    • 1842628561 scopus 로고    scopus 로고
    • Activation of resistance arteries with endothelin-1: From vasoconstriction to functional adaptation and remodeling
    • Bakker EN, Buus CL, VanBavel E, Mulvany MJ (2004) Activation of resistance arteries with endothelin-1: From vasoconstriction to functional adaptation and remodeling. J Vasc Res 41(2):174-182
    • (2004) J Vasc Res , vol.41 , Issue.2 , pp. 174-182
    • Bakker, E.N.1    Buus, C.L.2    VanBavel, E.3    Mulvany, M.J.4
  • 6
    • 33746198003 scopus 로고    scopus 로고
    • Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: Possible compensation by macrophage-derived factor XIII
    • Bakker EN, Pistea A, Spaan JA, Rolf T, de Vries CJ, van RN, Candi E, VanBavel E (2006) Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: Possible compensation by macrophage-derived factor XIII. Circ Res 99(1):86-92
    • (2006) Circ Res , vol.99 , Issue.1 , pp. 86-92
    • Bakker, E.N.1    Pistea, A.2    Spaan, J.A.3    Rolf, T.4    de Vries, C.J.5    van, R.N.6    Candi, E.7    VanBavel, E.8
  • 7
    • 0034011473 scopus 로고    scopus 로고
    • Organoid culture of cannulated rat resistance arteries: Effect of serum factors on vasoactivity and remodeling
    • Bakker EN, van Der Meulen ET, Spaan JA, VanBavel E (2001) Organoid culture of cannulated rat resistance arteries: Effect of serum factors on vasoactivity and remodeling. Am J Physiol 278:H1233-H1240
    • (2001) Am J Physiol , vol.278
    • Bakker, E.N.1    van Der Meulen, E.T.2    Spaan, J.A.3    VanBavel, E.4
  • 9
    • 0036150671 scopus 로고    scopus 로고
    • Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: A longitudinal study
    • Boutouyrie P, Tropeano AI, Asmar R, Gautier I, Benetos A, Lacolley P, Laurent S (2002) Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: A longitudinal study. Hypertension 39(1):10-15
    • (2002) Hypertension , vol.39 , Issue.1 , pp. 10-15
    • Boutouyrie, P.1    Tropeano, A.I.2    Asmar, R.3    Gautier, I.4    Benetos, A.5    Lacolley, P.6    Laurent, S.7
  • 10
    • 4644297102 scopus 로고    scopus 로고
    • Myocardial perfusion during long-term angiotensin-converting enzyme inhibition or beta-blockade in patients with essential hypertension
    • Buus NH, Bottcher M, Jorgensen CG, Christensen KL, Thygesen K, Nielsen TT, Mulvany MJ (2004) Myocardial perfusion during long-term angiotensin-converting enzyme inhibition or beta-blockade in patients with essential hypertension. Hypertension 44(4):465-470
    • (2004) Hypertension , vol.44 , Issue.4 , pp. 465-470
    • Buus, N.H.1    Bottcher, M.2    Jorgensen, C.G.3    Christensen, K.L.4    Thygesen, K.5    Nielsen, T.T.6    Mulvany, M.J.7
  • 11
    • 0035019959 scopus 로고    scopus 로고
    • Vasodilatation, not hypotension, improves resistance vessel design during treatment of essential hypertension: A literature survey
    • Christensen KL, Mulvany MJ (2001) Vasodilatation, not hypotension, improves resistance vessel design during treatment of essential hypertension: A literature survey. J Hypertens 19:1001-1006
    • (2001) J Hypertens , vol.19 , pp. 1001-1006
    • Christensen, K.L.1    Mulvany, M.J.2
  • 13
    • 0029075128 scopus 로고
    • Endothelium-dependent relaxation of small arteries from essential hypertensive patients: Mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats
    • Deng LY, Li JS, Schiffrin EL (1995) Endothelium-dependent relaxation of small arteries from essential hypertensive patients: Mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats. Clin Sci Colch 88:611-622
    • (1995) Clin Sci Colch , vol.88 , pp. 611-622
    • Deng, L.Y.1    Li, J.S.2    Schiffrin, E.L.3
  • 14
    • 0008659390 scopus 로고    scopus 로고
    • History of clinical hypertension: From 1827 to 1970
    • In: Oparil S, Weber MA (eds) Saunders WB, Philadelphia
    • Dustan HP (2000) History of clinical hypertension: From 1827 to 1970. In: Oparil S, Weber MA (eds) Hypertension. Saunders WB, Philadelphia, pp 1-4
    • (2000) Hypertension , pp. 1-4
    • Dustan, H.P.1
  • 16
    • 0028277661 scopus 로고
    • In vitro perfusion studies of human resistance artery function in essential hypertension
    • Falloon BJ, Heagerty AM (1994) In vitro perfusion studies of human resistance artery function in essential hypertension. Hypertension 24:16-23
    • (1994) Hypertension , vol.24 , pp. 16-23
    • Falloon, B.J.1    Heagerty, A.M.2
  • 17
    • 0036804796 scopus 로고    scopus 로고
    • Transglutaminase 2: An enigmatic enzyme with diverse functions
    • Fesus L, Piacentini M (2002). Transglutaminase 2: An enigmatic enzyme with diverse functions. Trends Biochem Sci 27(10):534-539
    • (2002) Trends Biochem Sci , vol.27 , Issue.10 , pp. 534-539
    • Fesus, L.1    Piacentini, M.2
  • 18
    • 0002275131 scopus 로고
    • Structural, myogenic, humoral and nervous factors controlling peripheral resistance
    • In: Harington M (ed) Pergamon, London
    • Folkow B (1956) Structural, myogenic, humoral and nervous factors controlling peripheral resistance. In: Harington M (ed) Hypotensive drugs. Pergamon, London, pp 163-174
    • (1956) Hypotensive Drugs , pp. 163-174
    • Folkow, B.1
  • 19
    • 0033390756 scopus 로고    scopus 로고
    • Candesartan cilexetil in hypertension: Effects of six weeks' treatment on haemodynamics, baroreceptor sensitivity and the renin-angiotensin-aldosterone system
    • Fridman KU, Wysocki M, Friberg PR, Andersson OK (1999) Candesartan cilexetil in hypertension: Effects of six weeks' treatment on haemodynamics, baroreceptor sensitivity and the renin-angiotensin-aldosterone system. Blood Press 8(4):242-247
    • (1999) Blood Press , vol.8 , Issue.4 , pp. 242-247
    • Fridman, K.U.1    Wysocki, M.2    Friberg, P.R.3    Andersson, O.K.4
  • 20
    • 0036901574 scopus 로고    scopus 로고
    • Transglutaminases: Nature's biological glues
    • Griffin M, Casadio R, Bergamini CM (2002) Transglutaminases: Nature's biological glues. Biochem J 368(Pt 2):377-396
    • (2002) Biochem J , vol.368 , Issue.PART 2 , pp. 377-396
    • Griffin, M.1    Casadio, R.2    Bergamini, C.M.3
  • 21
    • 0027511750 scopus 로고
    • Small artery structure in hypertension - Dual processes of remodeling and growth
    • Heagerty AM, Aalkjaer C, Bund SJ, Korsgaard N, Mulvany MJ (1993) Small artery structure in hypertension - dual processes of remodeling and growth. Hypertension 21(4):391-397
    • (1993) Hypertension , vol.21 , Issue.4 , pp. 391-397
    • Heagerty, A.M.1    Aalkjaer, C.2    Bund, S.J.3    Korsgaard, N.4    Mulvany, M.J.5
  • 23
    • 70449176295 scopus 로고    scopus 로고
    • Chlorothiazide: A new type of drug for the treatment of arterial hypertension
    • Hollander W, Wilkins RW (2007) Chlorothiazide: A new type of drug for the treatment of arterial hypertension. BMQ 8:69-71
    • (2007) BMQ , vol.8 , pp. 69-71
    • Hollander, W.1    Wilkins, R.W.2
  • 25
  • 26
    • 0032822226 scopus 로고    scopus 로고
    • Impact of calcium antagonists on the cardiovascular system: Experience with lacidipine
    • Kuschnir E (1999) Impact of calcium antagonists on the cardiovascular system: Experience with lacidipine. Drugs 57(Suppl 1):11-17
    • (1999) Drugs , vol.57 , Issue.SUPPL. 1 , pp. 11-17
    • Kuschnir, E.1
  • 27
    • 0014803646 scopus 로고
    • Hemodynamic changes in long-term diuretic therapy of essential hypertension. A comparative study of chlorthalidone, polythiazide and hydrochlorothiazide
    • Lund-Johansen P (1970) Hemodynamic changes in long-term diuretic therapy of essential hypertension. A comparative study of chlorthalidone, polythiazide and hydrochlorothiazide. Acta Med Scand 187(6):509-518
    • (1970) Acta Med Scand , vol.187 , Issue.6 , pp. 509-518
    • Lund-Johansen, P.1
  • 28
    • 0019196116 scopus 로고
    • Haemodynamics in essential hypertension
    • Lund-Johansson P (1980) Haemodynamics in essential hypertension. Clin Sci 59:343-354
    • (1980) Clin Sci , vol.59 , pp. 343-354
    • Lund-Johansson, P.1
  • 29
    • 0032751208 scopus 로고    scopus 로고
    • Sympathetic activation in the pathogenesis of hypertension and progression of organ damage
    • Mancia G, Grassi G, Giannattasio C, Seravalle G (1999) Sympathetic activation in the pathogenesis of hypertension and progression of organ damage. Hypertension 34(4 Pt 2):724-728
    • (1999) Hypertension , vol.34 , Issue.4 PART 2 , pp. 724-728
    • Mancia, G.1    Grassi, G.2    Giannattasio, C.3    Seravalle, G.4
  • 30
    • 3042821169 scopus 로고    scopus 로고
    • Acute mechanoadaptation of vascular smooth muscle cells in response to continuous arteriolar vasoconstriction: Implications for functional remodeling
    • Martinez-Lemus LA, Hill MA, Bolz SS, Pohl U, Meininger GA (2004) Acute mechanoadaptation of vascular smooth muscle cells in response to continuous arteriolar vasoconstriction: Implications for functional remodeling. Faseb J 18(6):708-710
    • (2004) Faseb J , vol.18 , Issue.6 , pp. 708-710
    • Martinez-Lemus, L.A.1    Hill, M.A.2    Bolz, S.S.3    Pohl, U.4    Meininger, G.A.5
  • 31
    • 34147141991 scopus 로고    scopus 로고
    • Small artery structure adapts to vasodilatation rather than to blood pressure during antihypertensive treatment
    • Mathiassen ON, Buus NH, Larsen ML, Mulvany MJ, Christensen KL (2007) Small artery structure adapts to vasodilatation rather than to blood pressure during antihypertensive treatment. J Hypertens 25(5):1027-1034
    • (2007) J Hypertens , vol.25 , Issue.5 , pp. 1027-1034
    • Mathiassen, O.N.1    Buus, N.H.2    Larsen, M.L.3    Mulvany, M.J.4    Christensen, K.L.5
  • 32
    • 33748355603 scopus 로고    scopus 로고
    • Forearm plethysmography in the assessment of vascular tone and resistance vasculature design: New methodological insights
    • Mathiassen ON, Buus NH, Olsen HW, Larsen ML, Mulvany MJ, Christensen KL (2006) Forearm plethysmography in the assessment of vascular tone and resistance vasculature design: New methodological insights. Acta Physiol (Oxf) 188(2):91-101
    • (2006) Acta Physiol (Oxf) , vol.188 , Issue.2 , pp. 91-101
    • Mathiassen, O.N.1    Buus, N.H.2    Olsen, H.W.3    Larsen, M.L.4    Mulvany, M.J.5    Christensen, K.L.6
  • 34
    • 0021863832 scopus 로고
    • MRC trial of treatment of mild hypertension: Principal results
    • Medical Research Council Working Party
    • Medical Research Council Working Party (1985) MRC trial of treatment of mild hypertension: Principal results. Br Med J 291:97-104
    • (1985) Br Med J , vol.291 , pp. 97-104
  • 35
    • 0017275447 scopus 로고
    • Mechanical properties of vascular smooth muscle cells in situ
    • Mulvany MJ, Halpern W (1976) Mechanical properties of vascular smooth muscle cells in situ. Nature 269:617-619
    • (1976) Nature , vol.269 , pp. 617-619
    • Mulvany, M.J.1    Halpern, W.2
  • 37
    • 1842867029 scopus 로고    scopus 로고
    • Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan
    • Omura M, Saito J, Yamaguchi K, Kakuta Y, Nishikawa T (2004) Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan. Hypertens Res 27(3):193-202
    • (2004) Hypertens Res , vol.27 , Issue.3 , pp. 193-202
    • Omura, M.1    Saito, J.2    Yamaguchi, K.3    Kakuta, Y.4    Nishikawa, T.5
  • 38
    • 33645528752 scopus 로고    scopus 로고
    • Pulsology rediscovered: Commentary on the conduit artery function evaluation (CAFE) study
    • Oparil S, Izzo JL Jr (2006) Pulsology rediscovered: Commentary on the conduit artery function evaluation (CAFE) study. Circulation 113(9):1162-1163
    • (2006) Circulation , vol.113 , Issue.9 , pp. 1162-1163
    • Oparil, S.1    Izzo Jr., J.L.2
  • 43
  • 44
    • 0036628766 scopus 로고    scopus 로고
    • Left ventricular remodeling impairs coronary flow reserve in hypertensive patients
    • Schafer S, Kelm M, Mingers S, Strauer BE (2002) Left ventricular remodeling impairs coronary flow reserve in hypertensive patients. J Hypertens 20(7):1431-1437
    • (2002) J Hypertens , vol.20 , Issue.7 , pp. 1431-1437
    • Schafer, S.1    Kelm, M.2    Mingers, S.3    Strauer, B.E.4
  • 45
    • 0029834907 scopus 로고    scopus 로고
    • Structure and function of resistance arteries of hypertensive patients treated with a beta-blocker or a calcium channel antagonist
    • Schiffrin EL, Deng LY (1996) Structure and function of resistance arteries of hypertensive patients treated with a beta-blocker or a calcium channel antagonist. J Hypertens 14(10):1247-1255
    • (1996) J Hypertens , vol.14 , Issue.10 , pp. 1247-1255
    • Schiffrin, E.L.1    Deng, L.Y.2
  • 46
    • 0346524356 scopus 로고
    • Effects of a beta-blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension
    • Schiffrin EL, Deng LY, Larochelle P (1994) Effects of a beta-blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension. Hypertension 23:83-91
    • (1994) Hypertension , vol.23 , pp. 83-91
    • Schiffrin, E.L.1    Deng, L.Y.2    Larochelle, P.3
  • 47
    • 0026533338 scopus 로고
    • Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients
    • Schiffrin EL, Deng LY, Larochelle P (1992) Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients. J. Hypertens 10:437-444
    • (1992) J. Hypertens , vol.10 , pp. 437-444
    • Schiffrin, E.L.1    Deng, L.Y.2    Larochelle, P.3
  • 48
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz RM (2000) Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation 101:1653-1659
    • (2000) Circulation , vol.101 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.M.4
  • 49
    • 0036060584 scopus 로고    scopus 로고
    • Effect of crossing over hypertensive patients from a beta-blocker to an angiotensin receptor antagonist on resistance artery structure and on endothelial function
    • Schiffrin EL, Park JB, Pu Q (2002) Effect of crossing over hypertensive patients from a beta-blocker to an angiotensin receptor antagonist on resistance artery structure and on endothelial function. J Hypertens 20(1):71-78
    • (2002) J Hypertens , vol.20 , Issue.1 , pp. 71-78
    • Schiffrin, E.L.1    Park, J.B.2    Pu, Q.3
  • 50
    • 0037058834 scopus 로고    scopus 로고
    • Vascular structural and functional changes in type 2 diabetes mellitus: Evidence for the roles of abnormal myogenic responsiveness and dyslipidemia
    • Schofield I, Malik R, Izzard A, Austin C, Heagerty A (2002) Vascular structural and functional changes in type 2 diabetes mellitus: Evidence for the roles of abnormal myogenic responsiveness and dyslipidemia. Circulation 106(24):3037-3043
    • (2002) Circulation , vol.106 , Issue.24 , pp. 3037-3043
    • Schofield, I.1    Malik, R.2    Izzard, A.3    Austin, C.4    Heagerty, A.5
  • 51
    • 0027164546 scopus 로고
    • Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension
    • Schwartzkopff B, Motz W, Frenzel H, Vogt M, Knauer S, Strauer BE (1993). Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension. Circulation 88(3):993-1003
    • (1993) Circulation , vol.88 , Issue.3 , pp. 993-1003
    • Schwartzkopff, B.1    Motz, W.2    Frenzel, H.3    Vogt, M.4    Knauer, S.5    Strauer, B.E.6
  • 52
    • 0031955583 scopus 로고    scopus 로고
    • Effect of antihypertensive treatment on cardiac and subcutaneous artery structure: A comparison between calcium channel blocker and thiazide-based regimens
    • Sihm I, Schroeder AP, Aalkjaer C, Mulvany MJ, Thygesen K, Lederballe O (1998) Effect of antihypertensive treatment on cardiac and subcutaneous artery structure: A comparison between calcium channel blocker and thiazide-based regimens. Am J Hypertens 11:263-271
    • (1998) Am J Hypertens , vol.11 , pp. 263-271
    • Sihm, I.1    Schroeder, A.P.2    Aalkjaer, C.3    Mulvany, M.J.4    Thygesen, K.5    Lederballe, O.6
  • 53
    • 34250829757 scopus 로고    scopus 로고
    • Treatment of young subjects at high familial risk of future hypertension with an angiotensin-receptor blocker
    • Skov K, Eiskjaer H, Hansen HE, Madsen JK, Kvist S, Mulvany MJ (2007) Treatment of young subjects at high familial risk of future hypertension with an angiotensin-receptor blocker. Hypertension 50(1):39-40
    • (2007) Hypertension , vol.50 , Issue.1 , pp. 39-40
    • Skov, K.1    Eiskjaer, H.2    Hansen, H.E.3    Madsen, J.K.4    Kvist, S.5    Mulvany, M.J.6
  • 54
    • 33748429170 scopus 로고    scopus 로고
    • Calcium channel blockade prevents pressure-dependent inward remodeling in isolated subendocardial resistance vessels
    • Sorop O, Bakker EN, Pistea A, Spaan JA, VanBavel E (2006) Calcium channel blockade prevents pressure-dependent inward remodeling in isolated subendocardial resistance vessels. Am J Physiol Heart Circ Physiol 291(3):H1236-H1245
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , Issue.3
    • Sorop, O.1    Bakker, E.N.2    Pistea, A.3    Spaan, J.A.4    VanBavel, E.5
  • 55
    • 0028351850 scopus 로고
    • Dose-dependent effects of perindopril on blood pressure and on small artery structure
    • Thybo NK, Korsgaard N, Eriksen S, Christensen KL, Mulvany MJ (1994) Dose-dependent effects of perindopril on blood pressure and on small artery structure. Hypertension 23:659-666
    • (1994) Hypertension , vol.23 , pp. 659-666
    • Thybo, N.K.1    Korsgaard, N.2    Eriksen, S.3    Christensen, K.L.4    Mulvany, M.J.5
  • 56
    • 0028929787 scopus 로고
    • Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension
    • Thybo NK, Stephens N, Cooper A, Aalkjaer C, Heagerty AM, Mulvany MJ (1995) Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension 25:474-481
    • (1995) Hypertension , vol.25 , pp. 474-481
    • Thybo, N.K.1    Stephens, N.2    Cooper, A.3    Aalkjaer, C.4    Heagerty, A.M.5    Mulvany, M.J.6
  • 57
    • 0035089266 scopus 로고    scopus 로고
    • Prognostic implications of left ventricular hypertrophy
    • Vakili BA, Okin PM, Devereux RB (2001) Prognostic implications of left ventricular hypertrophy. Am Heart J 141(3):334-341
    • (2001) Am Heart J , vol.141 , Issue.3 , pp. 334-341
    • Vakili, B.A.1    Okin, P.M.2    Devereux, R.B.3
  • 59
    • 0014200585 scopus 로고
    • Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg
    • Veterans Administration Cooperative Study
    • Veterans Administration Cooperative Study (1967) Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg. J Am Med Assoc 202:1028-1034
    • (1967) J Am Med Assoc , vol.202 , pp. 1028-1034


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.