Structure and function of resistance arteries of hypertensive patients treated with a β-blocker or a calcium channel antagonist

Journal of Hypertension

Volumn 14, Issue 10, 1996, Pages 1247-1255

  Schiffrin, Ernesto L ^a   Deng, Li Yuan ^b  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b NONE

Author keywords

Atenolol; Endothelium; Essential hypertension; Hypertrophy; Nifedipine; Small arteries; Vascular remodelling

Indexed keywords

ACETYLCHOLINE; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; NORADRENALIN;

ADULT; AGED; ARTERY DIAMETER; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; FEMALE; GLUTEUS MAXIMUS MUSCLE; HUMAN; HUMAN TISSUE; MALE; MUSCLE BIOPSY; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE RELAXATION; STRESS; STRUCTURE ACTIVITY RELATION; VASCULAR SMOOTH MUSCLE;

EID: 0029834907     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199610000-00014     Document Type: Article

References (50)

1. Folkow B: Physiological aspects of primary hypertension. Physiol Rev 1982, 62:347-504.
2. Mulvany MJ, Aalkjær C: Structure and function of small arteries. Physiol Rev 1990, 70:921-971
3. Schiffrin EL: Reactivity of small blood vessels in hypertension. Relationship with structural changes. Hypertension 1992, 19 (suppl II): II1-II9.
4. Heagerty AM, Aalkjær C, Bund SJ, Korsgaard N, Mulvany MJ: Small artery structure in hypertension: dual processes of remodeling and growth. Hypertension 1993, 21:391-397.
5. Chobanian A: Adaptive and maladaptive responses of the arterial wall to hypertension. Hypertension 1990, 15:666-674
6. Christensen KL, Mulvany MJ: Mesenteric arcade arteries contribute substantially to vascular resistance in conscious rats. J Vasc Res 1993, 30:73-79.
7. Folkow B: Hypertensive structural changes in systemic precapillary resistance vessels: how important are they for in vivo haemodynamics? J Hypertens 1995, 13:1546-1559.
8. Izzard AS, Heagerty AM: Hypertension and the vasculature: arterioles and the myogenic response. J Hypertens 1995, 13:1-4.
9. Spence JD: Cerebral consequences of hypertension. In Hypertension, Pathophysiology, Diagnosis and Management. Second edition. Edited by Laragh JH, Brenner BM. New York: Raven Press; 1995:741-753.
10. Ruilope LM, Alcázar JM, Rodicio JL: Renal consequences of hypertension. J Hypertens 1992, 10 (suppl 7):S85-S90.
11. Brush JE, Cannon RO, Schenke WH, Bonow RO, Leon MB, Maron BJ, et al.: Angina due to coronary microvascular disease in hypertensive patients without left ventricular hypertrophy. N Engl J Med 1988, 319: 1302-1307.
12. Fuster V, Badimon L, Badimon JJ, Chesebro JH: The pathogenesis of acute coronary syndromes. N Engl J Med 1992, 326:242-250, 310-318.
13. Veterans Administration Cooperative Study Group on Antihypertensive Agents: Effects of treatment on morbidity in hypertension, II: results in patients with diastolic blood pressure averaging 90 through 114mmHg. JAMA 1970, 202:1143-1152.
14. Australian National Blood Pressure Study Management Committee: Australian Therapeutic Trial in Mild Hypertension. Lancet 1980, i: 1262-1267.
15. Hypertension Detection and Follow-up Program Cooperative Group: The effect of treatment on mortality in mild hypertension. N Engl J Med 1982, 307:976-980.
16. Medical Research Council Working Party: MRC trial of treatment of mild hypertension: principal results. BMJ 1985, 291:97-104.
17. Medical Research Council Working Party: MRC trial of treatment of hypertension in older adults: principal results. BMJ 1992, 304: 405-412.
18. Schiffrin EL, Deng LY, Larochelle P: Effects of a beta blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension. Hypertension 1994, 23:83-91.
19. Schiffrin EL, Deng LY, Larochelle P: Progressive improvement in the structure of resistance arteries of hypertensive patients after 2 years of treatment with an angiotensin I-converting enzyme inhibitor. Comparison with effects of a beta blocker. Am J Hypertens 1995, 8: 229-236.
20. Thybo NK, Stephens N, Cooper A, Aalkjær C, Heagerty AM, Mulvany MJ: Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension 1995, 25: 474-481.
21. Schiffrin EL, Deng LY: Comparison of effects of angiotensin I-converting enzyme inhibition and beta blockade on function of small arteries from hypertensive patients. Hypertension 1995, 25:699-703.
22. Thybo NK, Korsgaard N, Eriksen S, Christensen KL, Mulvany MJ: Dose-dependent effects of perindopril on blood pressure and small-artery structure. Hypertension 1994, 23:659-666.
23. Li J-S, Schiffrin EL: Chronic endothelin receptor antagonist treatment of young spontaneously hypertensive rats. J Hypertens 1995, 13: 647-652.
24. Li J-S, Schiffrin EL: Effect of calcium channel blockade or angiotensin converting enzyme inhibition on structure of coronary, renal and other small arteries in SHR. J Cardiovasc Pharmacol 1996, 28:68-74.
25. Baumbach GL, Heistad DD: Remodeling of cerebral arterioles in chronic hypertension. Hypertension 1989, 13:968-972.
26. Aalkjær C, Heagerty AM, Petersen KK, Swales JD, Mulvany MJ: Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation-contraction coupling in isolated resistance vessels from essential hypertensives. Circ Res 1987, 61:181-186.
27. Schiffrin EL, Deng LY, Larochelle P: Morphology of resistance arteries and comparison of effects of vasoconstrictors in mild essential hypertensive patients. Clin Invest Med 1993, 16:177-186.
28. Rakowski H, Chan K-L, Dumesnil J, Rabkin S, for the Task Force on Echocardiography of the Canadian Cardiovascular Society and the Canadian Hypertension Society: Guidelines from the Canadian Cardiovascular Society and the Canadian Hypertension Society on the echocardiographic determination of left ventricular mass. Can J Cardiol 1995, 11:391-395.
29. Panza JA, Quyyumi AA, Brush JE, Epstein SE: Abnormal endothelium dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990, 323:22-27.
30. Deng LY, Li J-S, Schiffrin EL: Endothelium-dependent relaxation of small arteries from essential hypertensive patients. Clin Sci 1995, 88: 611-622.
31. Falloon BJ, Bund SJ, Tulip JR, Heagerty AM: In vitro perfusion studies of resistance artery function in genetic hypertension. Hypertension 1993, 22:486-495.
32. Touyz RM, Deng LY, Schiffrin EL: Endothelin subtype B receptor-mediated calcium and contractile responses in small arteries of hypertensive rats. Hypertension 1995, 26:1041-1045.
33. Hajdu MA, Baumbach GL: Mechanics of large and small cerebral arteries in chronic hypertension. Am J Physiol 1994, 266: H1027-H1033.
34. Lew JM, Angus JA: Wall thickness to lumen diameter ratios of arteries from SHR and WKY: comparison of pressurised and wire-mounted preparations. J Vasc Res 1992, 29:435-442.
35. Buus NH, VanBavel E, Mulvany MJ: Differences in sensitivity of rat mesenteric small arteries to agonists when studied as ring preparations or as cannulated preparations. Br J Pharmacol 1994, 112: 579-587.
36. Falloon BJ, Stephens N, Tulip JR, Heagerty AM: Comparison of small artery sensitivity and morphology in pressurized and wire-mounted preparations. Am J Physiol 1995, 268:H670-H678.
37. Schiffrin EL: Vascular structure in L-NAME-induced hypertension: methodological considerations for studies of small arteries in hypertension. J Hypertens 1995, 13:817-821.
38. Schiffrin EL: Effect of antihypertensive therapy on small artery structure in hypertensive patients [letter]. Hypertension 1995, 26:716-717.
39. Korsgaard N, Aalkjær C, Heagerty AM, Izzard AS, Mulvany MJ: Histology of subcutaneous small arteries from patients with essential hypertension. Hypertension 1993, 22:523-526.
40. Mulvany MJ, Baumbach GL, Aalkjær C, Heagerty AM, Korsgaard N, Schiffrin EL, et al.: Vascular remodeling [letter to the Editor]. Hypertension 1996, 28:505-506.
41. Agabiti Rosei E, Rizzoni D, Castellano M, Porteri E, Zulli R, Muiesan ML, et al.: Media:lumen ratio in human small resistance arteries is related to forearm minimal vascular resistance. J Hypertens 1995, 13:349-355.
42. Shaw LM, George PR, Oldham AA, Heagerty AM: A comparison of the effect of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism on the structural changes associated with hypertension in rat small arteries. J Hypertens 1995, 13:1135-1143.
43. Smith JB: Angiotensin-receptor signaling in cultured vascular smooth muscle cells. Am J Physiol 1986, 250:F759-F769.
44. Lund-Johansen P, Omvik P: Acute and chronic effects of drugs with different actions on adrenergic receptors: a comparison between alpha blockers and different types of beta blockers with and without vasodilating effect. Cardiovasc Drugs Ther 1991, 5:605-615.
45. Hajdu MA, Heistad DD, Baumbach GL: Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats. Hypertension 1991, 17:308-316.
46. Baumbach GL: Effects of increased pulse pressure on cerebral arterioles. Hypertension 1996, 27:159-167.
47. Hajdu MA, Heistad DD, Ghoneim S, Baumbach GL: Effects of antihypertensive treatment on composition of cerebral arterioles. Hypertension 1991, 18 (suppl II):II15-II21.
48. Bernink PJLM, Prager G, Schelling A, Kobrin I: Antihypertensive properties of the novel calcium channel antagonist mibefradil (Ro 40-5967). Hypertension 1996, 27:426-432.
49. MacMahon SW, Cutler JA, Stamler J: Antihypertensive drug treatment Potential, expected, and observed effects on stroke and on coronary heart disease. Hypertension 1989, 13 (suppl I):I45-I50.
50. Collins R, Peto F, MacMahon S, Herbert P, Fiebach NH, Eberlein KA, et al.: Blood pressure, stroke, and coronary heart disease, part 2: short term reductions in blood pressure: overview of randomized drug trials in their epidemiological context. Lancet 1990, 335:827-838.