The Ezrin-Radixin-Moesin family member Ezrin regulates stable microtubule formation and retroviral infection

Journal of Virology

Volumn 82, Issue 9, 2008, Pages 4665-4670

  Haedicke, Juliane ^a   De Los Santos, Kenia ^b   Goff, Stephen P ^b   Naghavi, Mojgan H ^a,b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EZRIN; MOESIN; RADIXIN;

ARTICLE; GENE AMPLIFICATION; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR CLONING; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS REPLICATION;

ANIMALS; CYTOSKELETAL PROTEINS; DISEASE SUSCEPTIBILITY; HIV-1; HUMANS; LEUKEMIA VIRUS, MURINE; MEMBRANE PROTEINS; MICE; MICROFILAMENT PROTEINS; MICROTUBULES; RATS; RETROVIRIDAE INFECTIONS; RNA, SMALL INTERFERING; TRANSFECTION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MURINE LEUKEMIA VIRUS;

EID: 42449159718     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02403-07     Document Type: Article

References (39)

1. Best, S., P. Le Tissier, G. Towers, and J. P. Stoye. 1996. Positional cloning of the mouse retrovirus restriction gene Fv1. Nature 382:826-829.
2. Bick, M. J., J. W. Carroll, G. Gao, S. P. Goff, C. M. Rice, and M. R. MacDonald. 2003. Expression of the zinc-finger antiviral protein inhibits alphavirus replication. J. Virol. 77:11555-11562.
3. Bieniasz, P. D. 2004. Intrinsic immunity: a front-line defense against viral attack. Nat. Immunol. 5:1109-1115.
4. Boulanger, M. C., C. Liang, R. S. Russell, R. Lin, M. T. Bedford, M. A. Weinberg, and S. Richard. 2005. Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression. J. Virol. 79:124-131.
5. Bretscher, A. 1999. Regulation of cortical structure by the ezrin-radixin-moesin protein family. Curr. Opin. Cell Biol. 11:109-116.
6. Bukrinskaya, A., B. Brichacek, A. Mann, and M. Stevenson. 1998. Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton. J. Exp. Med. 188: 2113-2125.
7. Cook, T. A., T. Nagasaki, and G. G. Gundersen. 1998. Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid. J. Cell Biol. 141:175-185.
8. Dohner, K., C. H. Nagel, and B. Sodeik. 2005. Viral stop-and-go along microtubules: taking a ride with dynein and kinesins. Trends Microbiol. 13:320-327.
9. Ganesh, L., E. Burstein, A. Guha-Niyogi, M. K. Louder, J. R. Mascola, L. W. Klomp, C. Wijmenga, C. S. Duckett, and G. J. Nabel. 2003. The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. Nature 426:853-857.
10. Gao, G., and S. P. Goff. 1999. Somatic cell mutants resistant to retrovirus replication: intracellular blocks during the early stages of infection. Mol. Biol. Cell 10:1705-1717.
11. Gao, G., X. Guo, and S. P. Goff. 2002. Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein. Science 297:1703-1706.
12. Hecker, C., C. Weise, J. Schneider-Schaulies, H. C. Holmes, and V. ter Meulen. 1997. Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin. Virus Res. 49:215-223.
13. Ikeda, H., and H. Sugimura. 1989. Fv-4 resistance gene: a truncated endogenous murine leukemia virus with ecotropic interference properties. J. Virol. 63:5405-5412.
14. Ivetic, A., and A. J. Ridley. 2004. Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology 112:165-176.
15. Janket, M. L., J. S. DeRicco, L. Borowski, and V. Ayyavoo. 2007. Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells. Virus Res. 126:76-85.
16. Kizhatil, K., and L. M. Albritton. 1997. Requirements for different components of the host cell cytoskeleton distinguish ecotropic murine leukemia virus entry via endocytosis from entry via surface fusion. J. Virol. 71:7145-7156.
17. Komano, J., K. Miyauchi, Z. Matsuda, and N. Yamamoto. 2004. Inhibiting the Arp2/3 complex limits infection of both intracellular mature vaccinia virus and primate lentiviruses. Mol. Biol. Cell 15:5197-5207.
18. Lin, S. X., G. G. Gundersen, and F. R. Maxfield. 2002. Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin. Mol. Biol. Cell 13:96-109.
19. Mangeat, B., and D. Trono. 2005. Lentiviral vectors and antiretroviral intrinsic immunity. Hum. Gene Ther. 16:913-920.
20. McDonald, D., M. A. Vodicka, G. Lucero, T. M. Svitkina, G. G. Borisy, M. Emerman, and T. J. Hope. 2002. Visualization of the intracellular behavior of HIV in living cells. J. Cell Biol. 159:441-452.
21. Naghavi, M. H., and S. P. Goff. 2007. Retroviral proteins that interact with the host cell cytoskeleton. Curr. Opin. Immunol. 19:402-407.
22. Naghavi, M. H., T. Hatziioannou, G. Gao, and S. P. Goff. 2005. Overexpression of fasciculation and elongation protein zeta-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells. Genes Dev. 19:1105-1115.
23. Naghavi, M. H., S. Valente, T. Hatziioannou, K. de los Santos, Y. Wen, C. Mott, G. G. Gundersen, and S. P. Goff. 2007. Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells. EMBO J. 26:41-52.
24. Naranatt, P. P., H. H. Krishnan, M. S. Smith, and B. Chandran. 2005. Kaposi's sarcoma-associated herpesvirus modulates microtubule dynamics via RhoA-GTP-diaphanous 2 signaling and utilizes the dynein motors to deliver its DNA to the nucleus. J. Virol. 79:1191-1206.
25. Ng, T., M. Parsons, W. E. Hughes, J. Monypenny, D. Zicha, A. Gautreau, M. Arpin, S. Gschmeissner, P. J. Verveer, P. I. Bastiaens, and P. J. Parker. 2001. Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility. EMBO J. 20:2723-2741.
26. Ott, D. E., L. V. Coren, B. P. Kane, L. K. Busch, D. G. Johnson, R. C. Sowder II, E. N. Chertova, L. O. Arthur, and L. E. Henderson. 1996. Cytoskeletal proteins inside human immunodeficiency virus type 1 virions. J. Virol. 70: 7734-7743.
27. Palazzo, A. F., T. A. Cook, A. S. Alberts, and G. G. Gundersen. 2001. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat. Cell Biol. 3:723-729.
28. Prag, S., M. Parsons, M. D. Keppler, S. M. Ameer-Beg, P. Barber, J. Hunt, A. J. Beavil, R. Calvert, M. Arpin, B. Vojnovic, and T. Ng. 2007. Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42. Mol. Biol. Cell 18:2935-2948.
29. Sheehy, A. M., N. C. Gaddis, J. D. Choi, and M. H. Malim. 2002. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418:646-650.
30. Stremlau, M., C. M. Owens, M. J. Perron, M. Kiessling, P. Autissier, and J. Sodroski. 2004. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 427:848-853.
31. Takahashi, K., T. Sasaki, A. Mammoto, K. Takaishi, T. Kameyama, S. Tsukita, and Y. Takai. 1997. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. J. Biol. Chem. 272:23371-23375.
32. Taunton, J. 2001. Actin filament nucleation by endosomes, lysosomes and secretory vesicles. Curr. Opin. Cell Biol. 13:85-91.
33. Tsukita, S., and S. Yonemura. 1999. Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins. J. Biol. Chem. 274:34507-34510.
34. Turelli, P., B. Mangeat, S. Jost, S. Vianin, and D. Trono. 2004. Inhibition of hepatitis B virus replication by APOBEC3G. Science 303:1829.
35. Vanni, C., A. Parodi, P. Mancini, V. Visco, C. Ottaviano, M. R. Torrisi, and A. Eva. 2004. Phosphorylation-independent membrane relocalization of ezrin following association with Dbl in vivo. Oncogene 23:4098-4106.
36. Wei, B. L., V. K. Arora, A. Raney, L. S. Kuo, G. H. Xiao, E. O'Neill, J. R. Testa, J. L. Foster, and J. V. Garcia. 2005. Activation of p21-activated kinase 2 by human immunodeficiency virus type 1 Nef induces merlin phosphorylation. J. Virol. 79:14976-14980.
37. Wen, Y., C. H. Eng, J. Schmoranzer, N. Cabrera-Poch, E. J. Morris, M. Chen, B. J. Wallar, A. S. Alberts, and G. G. Gundersen. 2004. EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nat. Cell Biol. 6:820-830.
38. Zhang, J., E. Attar, K. Cohen, C. Crumpacker, and D. Scadden. 2005. Silencing p21(Waf1/Cip1/Sdi1) expression increases gene transduction efficiency in primitive human hematopoietic cells. Gene Ther. 12:1444-1452.
39. Zhang, J., D. T. Scadden, and C. S. Crumpacker. 2007. Primitive hematopoietic cells resist HIV-1 infection via p21. J. Clin. Investig. 117:473-481.