Ultrastructure of the blood-brain barrier of the gyrus hippocampal cortex in an experimental model of febrile seizures and with the use of a new generation antiepileptic drug - Topiramate

Folia Neuropathologica

Volumn 46, Issue 1, 2008, Pages 57-68

  Łotowska, Joanna M ^a   Sobaniec Łotowska, Maria E ^a   Sendrowski, Krzysztof ^a   Sobaniec, Wojciech ^a   Artemowicz, Barbara ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Blood brain barrier; Febrile seizures; Hippocampal cortex; Rats; Topiramate; Ultrastructure

Indexed keywords

TOPIRAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD VESSEL OCCLUSION; BRAIN CAPILLARY; CELL DAMAGE; CELL SWELLING; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOPATHOLOGY; ENDOTHELIUM CELL; ENDOTHELIUM LESION; FEBRILE CONVULSION; MALE; NEUROPROTECTION; NONHUMAN; RAT; SUBICULUM; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM;

EID: 42449154217     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Carlsson C, Hagerdal M, Siesjö BK. The effect of hyperthermia upon oxygen consumption and upon organic phosphates, glycolytic metabolites, citric and cycle intermediates and associated amino acids in rat cerebral cortes. J Neurochem 1976; 26: 1001-1006.
2. Cornford EM, Oldendorf WH. Epilepsy and the blood-brain barrier. Adv Neurol 1986; 44: 787-812.
3. Dydyk L, Pluta R. influence of hyperthermia on ultrastructure of the cerebral cortex and subcortical white matter in rabbits. Neuropat Pol 1984; 22: 97-115.
4. Edmonds HL Jr, Jiang YD, Zhang PY, Shank R. Topiramate as a neuroprotectant in a rat model of global ischemia-induced neurodegeneration. Life Sci 2001; 69: 2265-2277.
5. Gadomski R, Lasocki R. Morphological changes and acid phosphatase and thiamine pyrophosphatase activity in reticular formation nuclei and neurosecretive nuclei on the hypothalamus in rabbits subjected to environment hyperthermia. Neuropat Pol 1985; 23: 83-96.
6. Gibbs JW 3rd, Sombati S, DeLorenzo RJ, Coulter DA. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 2000; 41 (Suppl 1): S10-S16.
7. Kapuściński A, Karczewski WA. The effects of hyperventilation on the cerebral blood flow in normo - and hyperthermic rabbits. IRCS Medical Science 1973; (73-11): 11-1-22.
8. Kirino T, Tamura A, Sano K. Selective vulnerability of the hippocampus to ischemia - reversible and irreversible types of ischemic cell damage. Frog Brain Res 1985; 63: 39-58.
9. Knudsen FU. Febrile seizures: treatment prognosis. Epilepsia 2000; 41: 2-9.
10. Kudin AP, Debska-Vielhaber G, Vielhaber S, Elger CE, Kunz WS. The mechanism of neuroprotection by topiramate in an animal model of epilepsy. Epilepsia 2004; 45: 1478-1487.
11. Lee SR, Kim SP, Kim JE. Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils. Neurosci Lett 2000; 281: 183-186.
12. Majkowska-Wierzbicka J. Experimental global cerebral ischemia in rats. I. Ultrastructural changes in cerebral cortex in the postischemic period. Neuropath Pol 1989; 27: 97-114.
13. Mathern GW, Babb TL, Armstrong DL. Hippocampal sclerosis. In: Engel JJ, Pedley TA (eds). Epilepsy: A comprehensive textbook. Philadelphia, Lippincott-Raven 1997; pp. 133-155.
14. Mossakowski MJ, Gajkowska B, Tsitsishvili A. Ultrastructure of neurons from the CA1 sector of Ammon's horn in short-term cerebral ischemia in Mongolian gerbils. Neuropath Pol 1989; 27: 39-53.
15. Niebauer M, Gruenthal M. Topiramate reduces neuronal injury after experimental status epilepticus. Brain Res 1999; 837: 263-269.
16. Oby E, Janigro D. The blood-brain barrier and epilepsy. Epilepsia 2006; 47: 1761-1774.
17. Poulsen CF, Simeone TA, Maar TE, Smith-Swintosky, White HS, Schousboe A. Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons. Neurochem Res 2004; 29: 275-282.
18. Scott RC, King MD, Gadian DG, Neville BG, Connelly A. Hippocampal abnormalities after prolonged febrile convulsion: a longitudinal MRI study. Brain 2003; 126: 2551-2557.
19. Sendrowski K, Sobaniec-Łotowska ME, Sobaniec W. Ultrastructure of hippocampal capillaries in experimental valproate encephalopathy. Eur J Paediatric Neurology 2003; 7: A25-A26 (Abstr.).
20. Sendrowski K, Sobaniec W, Sobaniec-Łotowska ME, Artemowicz B. Topiramate as a neuroprotectant in the experimental model of febrile seizures. Adv Med Sci 2007; 52 (Suppl 1): 161-165.
21. Sendrowski K, Sobaniec W, Sobaniec-Łotowska ME, Artemowicz B. Neuroprotective effect of topiramate in the experimental model of febrile seizures. Child Neurology 2007; 16: 69
22. Shank RP, Gardocki JF, Streeter AJ, Maryanoff BE. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action. Epilepsia 2000; 41 (Suppl 1): S3-S9.
23. Smith-Swintosky VL, Zhao B, Shank RP, Plata-Salaman CR. Topiramate promotes neurite outgrowth and recovery of function after nerve injury. Neuroreport 2001; 12: 1031-1034.
24. Sobaniec-Łotowska ME, Sobaniec W. Morphological features of encephalopathy after chronic administration of the antiepileptic drug valproate to rats. A transmission electron microscopic study of capillaries in the cerebellar cortex. Exp Toxicol Pathol 1996; 48: 65-75.
25. Sobaniec-Łotowska ME, Sobaniec H, Sobaniec W, Sendrowski K. Electron microscopic studies of capillaries in the temporal lobe neocortex in experimental valproate encephalopathy. Actuelle Neurologie 2000; Suppl 2: 159 (Abstr.).
26. Sobaniec-Łotowska M, Sobaniec W, Augustynowicz A. Morphometric analysis of the cerebellar cortex capillaries in the course of experimental sodium valproate encephalopathy and after chronic exposure to sodium valproate using transmission electron microscopy. Folia Neuropathol 2001; 39: 277-280.
27. Strosznajder R, Gadamski R, Walski M. Inhibition of poly(ADP-ribose) polymerase activity protects hippocampal cells against morphological and ultrastructural alteration evoked by ischemia-reperfusion injury. Folia Neuropathol 2005; 43: 156-165.
28. Urakawa M, Yamaguchi K, Tsuchida E, Kashiwagi S, Ito H, Matsuda T. Blood-brain barrier disturbance following localized hyperthermia in rats. Int J Hyperthermia 1995; 11: 709-718.
29. Walski M, Borowicz J. Ultrastructural changes in the hypothalamic secretory nuclei of rats depending on the duration of clinical death. J Hirnforsch 1991; 32: 93-101.
30. Wojtal K, Borowicz KK, Błaszczyk B, Czuczwar SJ. Interactions of excitatory amino acid receptor antagonists with antiepileptic drugs in three basic models of experimental epilepsy. Pharmacol Rep 2006; 58: 587-598.