Effect of local viral transfer of interleukin 10 gene on a rabbit arthritis model induced by interleukin 1β

Chinese Medical Journal

Volumn 121, Issue 5, 2008, Pages 435-438

  Zhang, Ning ^a   Cui, Hua Dong ^a   Xue, Hong Xia ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Animal model; Arthritis rheumatoid; Gene therapy; Interleukin; Retrovirus

Indexed keywords

INTERLEUKIN 1BETA; MESSENGER RNA; RECOMBINANT INTERLEUKIN 10; RETROVIRUS VECTOR; INTERLEUKIN 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FEASIBILITY STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; KNEE ARTHRITIS; NONHUMAN; PROTEIN EXPRESSION; RABBIT; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; ARTHRITIS; DISEASE MODEL; GENE THERAPY; GENE VECTOR; GENETICS; RETROVIRUS;

ANIMALS; ARTHRITIS; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENETIC VECTORS; INTERLEUKIN-10; INTERLEUKIN-1BETA; RABBITS; RETROVIRIDAE; RNA, MESSENGER;

EID: 42449153787     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200803010-00013     Document Type: Article

References (21)

1. Terzioglu E, Bisgin A, Sanlioglu AD, Ulker M, Yazisiz V, Tuzuner S, et al. Concurrent gene therapy strategies effectively destroy synoviocytes of patients with rheumatoid arthritis. Rheumatology (Oxford) 2007; 46: 783-789.
2. van de Loo FA, Geurts J, van den Berg WB. Gene therapy works in animal model of rheumatoid arthritis. Curr Rheumatol Rep 2006; 8: 386-393.
3. Tarner IH, Neumann E, Gay S, Fathman CG, Muller-Ladner U. Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis. Autoimmun Rev 2006; 5: 148-152.
4. Tolusso B, Pietrapertosa D, Morelli A, De Santis M, Gremese E, Farina G, et al. IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy. Pharmacogenomics 2006; 7: 683-695.
5. Adriaansen J, Vervoordeldonk MJ, Tak PP. Gene therapy as a therapeutic approach for the treatment of rheumatoid arthritis: innovative vectors and therapeutic genes. Rheumatology (Oxford) 2066; 45: 656-668.
6. Woods AM, Thompson SJ, Wooley PH, Panayi G, Klavinskis LS. Immune modulation of collagen-induced arthritis by intranasal cytokine gene delivery: a model for the therapy of rheumatoid arthritis. Arthritis Rheum 2005; 52: 3761-3771.
7. Ghivizzani SC, Kang R, Georgeseu HI, Lechman ER, Jaffurs D, Engle JM, et al. Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J Immunol 1997; 159: 3604-3612.
8. van de Loo FA, van den Berg WB. Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators. Rheum Dis Clin North Am 2002; 28:127-149.
9. Fleming SB, Anderson IE, Thomson J, Deane DL, McInnes CJ, McCaughan CA, et al. Infection with recombinant orf viruses demonstrates that the viral interleukin-10, is a virulence factor. J Gen Virol 2007; 88: 1922-1927.
10. Li J, Bonneau L, Zimmerman J, Weiss D. Perfluorochemical (PFC) liquid enhances recombinant adenovinis vector-mediated viral interleukin-10 (AdvIL-10) expression in rodent lung. J Inflamm (Lond) 2007; 4: 9.
11. Otani K, Nita I, Macaulay W, Georgescu HI, Robbins PD, Evans CH. Suppression of antigen-induced arthritis by gene therapy. J Immunol 1996; 156: 3558-3562.
12. Makarov SS, Olsen JC, Johnston WN, Anderle SK, Brown RR, Baldwin AS Jr, et al. Suppression of experimental arthritis by gene transfer of interleukin-1 receptor antagonist cDNA. Proc Natl Acad Sci U S A 1996; 93: 402-406.
13. Lechman ER, Jaffurs D, Ghivizzani SC, Gambotto A, Kovesdi I, Mi Z, et al. Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees. J Immunol 1999; 163: 2202-2208.
14. Whalen JD, Lechman EL, Carlos CA, Weiss K, Kovesdi I, Glorioso JC, et al. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen induced arthritis in both injected and uninjected paws. J Immunol 1999; 162: 3625-3632.
15. Gong N, Pleyer U, Volk HD, Ritter T. Effects of local and systemic viral interleukin-10 gene transfer on corneal allograft survival. Gene Ther 2007; 14: 484-490.
16. Zhao J, Pettigrew GJ, Boltort EM, Murfitt CR, Carmichael A, Bradley JA, et al. Lentivirus- mediated gene transfer of viral interleukin-10 delays but does not prevent cardiac allograft rejection. Gene Ther 2005; 12: 1509-1516.
17. Chen B, Kapturczak MH, Joseph. R, George JF, Campbell-Thompson M, Wasserfall CH, et al. Adenoassociated viral vector-mediated interleukin-10 prolongs allograft survival in a rat kidney transplantation model. Am J Transplant 2007; 7: 1412-1120.
18. Salgar SK, Yang D, Ruiz P, Miller J, Tzakis AG. Viral interleukin-10 gene therapy to induce tolerance to solid organ transplants in mice. Transplant Proc 2004; 36: 397-398.
19. Salgar SK, Yang D, Ruiz P, Miller J, Tzakis AG Viral interleukin-10-engineered autologous hematopoietic stem cell therapy: anovel gene therapy approach to prevent graft rejection. Hum Gene Ther 2004; 15: 131-144.
20. Keravala A, Lechman ER, Nash J, Mi Z, Robbins PD. Human, viral. or mutant human IL-10 expressed after, local adenovirus-mediated gene transfer are equally effecfive in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis. Arthritis Res Ther 2006; 8: R91.
21. Kim KN, Watanabe S, Ma Y, Thornton S. Giannini EH, Hirsch R. Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus mediated gene transfer. J Immunol 2000; 164: 1576-1581.