Role of haptoglobin on the uptake of native and β-chain [trimesoyl-(Lys82)β-(Lys82)β] cross-linked human hemoglobins in isolated perfused rat livers

Drug Metabolism and Disposition

Volumn 36, Issue 5, 2008, Pages 937-945

  Chow, Edwin C Y ^a   Liu, Lichuan ^a,b   Ship, Noam ^a   Kluger, Ronald H ^a   Pang, K Sandy ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA [TRIMESOYL (LYSINE82)BETA (LYSINE82)BETA]; HAPTOGLOBIN; HEMOGLOBIN; HEMOGLOBIN BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; COMPARTMENT MODEL; CONTROLLED STUDY; CROSS LINKING; DRUG UPTAKE; GEL FILTRATION CHROMATOGRAPHY; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; LIVER CLEARANCE; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; RADIOACTIVITY; RAT;

ANIMALS; BILE; HAPTOGLOBINS; HEMOGLOBINS; HUMANS; LIVER; MALE; MODELS, BIOLOGICAL; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SALICYLATES;

RATTUS;

EID: 42449127111     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.019174     Document Type: Article

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