Cytokine generation, promoter activation, and oxidant-independent NF-κB activation in a transfectable human neutrophilic cellular model

BMC Immunology

Volumn 9, Issue , 2008, Pages

  Ear, Thornin ^a   McDonald, Patrick P ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; DIMETHYL SULFOXIDE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GAMMA INTERFERON; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LUCIFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; STAT PROTEIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR; OXIDIZING AGENT;

ARTICLE; CELL DIFFERENTIATION; CELL DISRUPTION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INACTIVATION; GENE ACTIVATION; GENETIC TRANSFECTION; GRANULOCYTE; HUMAN; HUMAN CELL; MOLECULAR MODEL; NEUTROPHIL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RELIABILITY; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; BIOSYNTHESIS; CYTOLOGY; FLOW CYTOMETRY; METABOLISM;

CELL DIFFERENTIATION; CYTOKINES; FLOW CYTOMETRY; GRANULOCYTES; HUMANS; MODELS, BIOLOGICAL; NEUTROPHILS; NF-KAPPA B; OXIDANTS; PROMOTER REGIONS (GENETICS); TRANSFECTION;

EID: 42449123156     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-9-14     Document Type: Article

References (54)

1. Cassatella MA Neutrophil-derived proteins: Selling cytokines by the pound Adv Immunol 1999, 73:369-509. 10399011
2. Xing Z Jordana M Kirpalani H Driscoll KE Schall TJ Gauldie J Cytokine expression by neutrophils and macrophages in vivo: Endotoxin induces tumor necrosis factor-α, macrophage inflammatory protein-2, interleukin-1β, and interleukin-6 but not RANTES or transforming growth factor-β1 mRNA expression in acute lung inflammation Am J Respir Cell Mol Biol 1994, 10:148-153. 8110470
3. Ivey CL Williams FM Collins PD Jose PJ Williams TJ Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit. Evidence for a role for C5a and interleukin-8 J Clin Invest 1995, 95:2720-2728. 295955 7769111 10.1172/JCI117974
4. Bennouna S Bliss SK Curiel TJ Denkers EY Cross-talk in the innate immune system: Neutrophils instruct recruitment and activation of dendritic cells during microbial infection J Immunol 2003, 171(11):6052-6058. 14634118
5. Bennouna S Denkers EY Microbial antigen triggers rapid mobilization of TNF-α to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-α production J Immunol 2005, 174(8):48450-4851. 15814711
6. von Stebut E Metz M Milon G Knop J Maurer M Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1α/ β released from neutrophils recruited by mast cell-derived TNFα Blood 2003, 101(1):210-215. 10.1182/blood-2002-03-0921 12393677
7. Wipke BT Allen PM Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis J Immunol 2001, 167(3):1601-1608. 11466382
8. Jonsson H Allen P Peng SL Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis Nat Med 2005, 11(6):666-671. 10.1038/nm1248 15895074
9. Mary JY Normal human granulopoiesis revisited. I. Blood data Biomed Pharmacother 1984, 38(1):33-43. 6380606
10. Tucker KA Lilly MB Heck L Jr. Rado TA Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity Blood 1987, 70(2):372-378. 3475136
11. Shen Q Chada S Whitney C Newburger PE Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation Blood 1994, 84(11):3902-3908. 7949146
12. Monczak Y Trudel M Lamph WW Miller WH Jr. Induction of apoptosis without differentiation by retinoic acid in PLB-985 cells requires the activation of both RAR and RXR Blood 1997, 90(9):3345-3355. 9345016
13. Lowenthal A Levy R Essential requirement of cytosolic phospholipase A2 for activation of the H(+) channel in phagocyte-like cells J Biol Chem 1999, 274(31):21603-21608. 10.1074/jbc.274.31.21603 10419467
14. Dana R Leto TL Malech HL Levy R Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase J Biol Chem 1998, 273:441-445. 10.1074/jbc.273.1.441 9417101
15. Pessach I Levy R The NADPH oxidase diaphorase activity in permeabilized human neutrophils and granulocytic like PLB-985 cells Adv Exp Med Biol 2000, 479:107-114. 10897413
16. Dana RR Eigsti C Holmes KL Leto TL A regulatory role for ADP-ribosylation factor 6 (ARF6) in activation of the phagocyte NADPH oxidase J Biol Chem 2000, 275(42):32566-32571. 10.1074/jbc.M005406200 10931844
17. Pedruzzi E Fay M Elbim C Gaudry M Gougerot-Pocidalo MA Differentiation of PLB-985 myeloid cells into mature neutrophils, shown by degranulation of terminally differentiated compartments in response to N-formyl peptide and priming of superoxide anion production by granulocyte-macrophage colony-stimulating factor Br J Haematol 2002, 117(3):719-726. 10.1046/j.1365-2141.2002.03521.x 12028049
18. Mankelow TJ Pessach E Levy R Henderson LM The requirement of cytosolic phospholipase A2 for the PMA activation of proton efflux through the N-terminal 230-amino-acid fragment of gp91phox Biochem J 2003, 374(Pt 2):315-319. 1223598 12765544 10.1042/BJ20030495
19. Hiraoka W Vazquez N Nieves-Neira W Chanock SJ Pommier Y Role of oxygen radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells J Clin Invest 1998, 102(11):1961-1968. 509148 9835621 10.1172/JCI3437
20. Gaudreault E Thompson C Stankova J Rola-Pleszczynski M Involvement of BLT1 endocytosis and Yes kinase activation in leukotriene B4-induced neutrophil degranulation J Immunol 2005, 174(6):3617-3625. 15749899
21. Hao LJ Yang D Fujii Y Yamauchi A Suzuki N Kikuchi H Kaneda Y Nakamura M Phorbol ester-potentiated liposomal transfection to monocytic PLB-985 cells J Biochem (Tokyo) 2000, 128(6):989-998. 11098142
22. Boulven I Levasseur S Marois S Pare G Rollet-Labelle E Naccache PH Class IA phosphatidylinositide 3-kinases, rather than p110γ, regulate formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis and superoxide production in differentiated neutrophil-like PLB-985 cells J Immunol 2006, 176(12):7621-7627. 16751409
23. Liberty IF Raichel L Hazan-Eitan Z Pessach I Hadad N Schlaeffer F Levy R Cytosolic phospholipase A2 is responsible for prostaglandin E2 and leukotriene B4 formation in phagocyte-like PLB-985 cells: Studies of differentiated cPLA2-deficient PLB-985 cells J Leukoc Biol 2004, 76(1):176-184. 10.1189/jlb.1003453 15123778
24. Cassatella MA Bazzoni F Calzetti F Guasparri I Rossi F Trinchieri G Interferon-γ transcriptionally modulates the expression of the genes for the high affinity IgG-Fc receptor and the 47-kDa cytosolic component of NADPH oxidase in human polymorphonuclear leukocytes J Biol Chem 1991, 266(33):22079-22082. 1834666
25. Kasama T Strieter RM Standiford TJ Burdick MD Kunkel SL Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1α J Exp Med 1993, 178:63-72. 10.1084/jem.178.1.63 8315395
26. Kasama T Strieter RM Lukacs NW Burdick MD Kunkel SL Regulation of neutrophil-derived chemokine expression by IL-10 J Immunol 1994, 152:3559-3569. 8144935
27. Cassatella MA Meda L Bonora S Ceska M Constantin G Interleukin-10 inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of TNF and IL-1β in mediating the production of IL-8 triggered by lipopolysaccharide J Exp Med 1993, 178:2207-2211. 10.1084/jem.178.6.2207 8245792
28. Cassatella MA Gasperini S Calzetti F Bertagnin A Luster AD McDonald PP Regulated production of the interferon-γ-inducible protein-10 (IP-10) chemokine by human neutrophils Eur J Immunol 1997, 27:111-115. 10.1002/eji.1830270117 9022006
29. Palombella VJ Rando OJ Goldberg AL Maniatis T The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB Cell 1994, 78(5):773-785. 10.1016/ S0092-8674(94)90482-0 8087845
30. Zavrski I Krebbel H Wildemann B Heider U Kaiser M Possinger K Sezer O Proteasome inhibitors abrogate osteoclast differentiation and osteoclast function Biochem Biophys Res Commun 2005, 333(1):200-205. 10.1016/ j.bbrc.2005.05.098 15936724
31. McDonald PP Bald A Cassatella MA Activation of the NF-κB pathway by inflammatory stimuli in human neutrophils Blood 1997, 89:3421-3433. 9129050
32. Wehinger J Gouilleux F Groner B Finke J Mertelsmann R Weber-Nordt RM IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes FEBS Lett 1996, 394(3):365-370. 10.1016/ 0014-5793(96)00990-8 8830676
33. Zhong Z Wen Z Darnell JE Jr. Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 Science 1994, 264(5155):95-98. 10.1126/science.8140422 8140422
34. McDonald PP Bovolenta C Cassatella MA Activation of distinct transcription factors in neutrophils by bacterial LPS, interferon-γ, and GM-CSF and the necessity to overcome the action of endogenous proteases Biochemistry 1998, 37:13165-13173. 10.1021/ bi972539o 9748323
35. Bovolenta C Gasperini S McDonald PP Cassatella MA High affinity receptor for IgG (FcγRI/CD64) gene and STAT protein binding to the IFNγ response region (GRR) are regulated differentially in human neutrophils and monocytes by IL-10 J Immunol 1998, 160:911-919. 9551929
36. Cloutier A Ear T Borissevitch O Larivee P McDonald PP Inflammatory cytokine expression is independent of the c-Jun N-terminal kinase/AP-1 signaling cascade in human neutrophils J Immunol 2003, 171(7):3751-3761. 14500675
37. Cloutier A Ear T Blais-Charron E Dubois CM McDonald PP Differential involvement of NF-κB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils J Leukoc Biol 2007:567-577. 10.1189/jlb.0806536 17062602
38. Cassatella MA Gasperini S Calzetti F McDonald PP Trinchieri G Lipopolysaccharide-induced interleukin-8 gene expression in human granulocytes: Transcriptional inhibition by interferon-γ Biochem J 1995, 310:751-735. 1135962 7575406
39. Tamassia N Le Moigne V Calzetti F Donini M Gasperini S Ear T Cloutier A Martinez FO Fabbri M Locati M Mantovani A McDonald PP Cassatella MA The MyD88-independent pathway is not mobilized in human neutrophils stimulated via TLR4 J Immunol 2007, 178(11):7344-7356. 17513785
40. Janssen-Heininger YM Poynter ME Baeuerle PA Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB Free Radic Biol Med 2000, 28(9):1317-1327. 10.1016/ S0891-5849(00)00218-5 10924851
41. Arrigo AP Gene expression and the thiol redox state Free Radic Biol Med 1999, 27(9-10):936-944. 10.1016/S0891-5849(99)00175-6 10569626
42. Zhen L King AA Xiao Y Chanock SJ Orkin SH Dinauer MC Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox Proc Natl Acad Sci U S A 1993, 90(21):9832-9836. 47666 8234321 10.1073/ pnas.90.21.9832
43. Yu L Cross AR Zhen L Dinauer MC Functional analysis of NADPH oxidase in granulocytic cells expressing a Δ488-497 gp91(phox) deletion mutant Blood 1999, 94(7):2497-2504. 10498623
44. Kaur N Lu B Monroe RK Ward SM Halvorsen SW Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/STAT signaling in neurons J Neurochem 2005, 92(6):1521-1530. 10.1111/ j.1471-4159.2004.02990.x 15748169
45. Pawate S Shen Q Fan F Bhat NR Redox regulation of glial inflammatory response to lipopolysaccharide and interferon-γ J Neurosci Res 2004, 77(4):540-551. 10.1002/jnr.20180 15264224
46. Ear T Cloutier A McDonald PP Constitutive nuclear expression of the IκB kinase complex and its activation in human neutrophils J Immunol 2005, 175(3):1834-1842. 16034126
47. Tamassia N Calzetti F Ear T Cloutier A Gasperini S Bazzoni F McDonald PP Cassatella MA Molecular mechanisms underlying the synergistic induction of CXCL10 by LPS and IFNγ in human neutrophils Eur J Immunol 2007, 37:2627-2634. 10.1002/eji.200737340 17668902
48. Selmeczy Z Szelenyi J Nemet K Vizi ES The inducibility of TNFα production is different in the granulocytic and monocytic differentiated forms of wild type and CGD-mutant PLB-985 cells Immunol Cell Biol 2003, 81(6):472-479. 10.1046/j.1440-1711.2003.01190.x 14636244
49. Vollebregt M Hampton MB Winterbourn CC Activation of NF-κB in human neutrophils during phagocytosis of bacteria independently of oxidant generation FEBS Lett 1998, 432(1-2):40-44. 10.1016/ S0014-5793(98)00821-7 9710247
50. Pietarinen-Runtti P Lakari E Raivio KO Kinnula VL Expression of antioxidant enzymes in human inflammatory cells Am J Physiol Cell Physiol 2000, 278(1):C118-25. 10644519
51. Achilli C Ciana A Rossi A Balduini C Minetti G Neutrophil granulocytes uniquely express, among human blood cells, high levels of methionine-sulfoxide-reductase enzymes J Leukoc Biol 2008, 83(1):181-189. 10.1189/jlb.0707492 17938273
52. Vlahopoulos S Boldogh I Casola A Brasier AR Nuclear factor-κB-dependent induction of interleukin-8 gene expression by tumor necrosis factor-α: Evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation Blood 1999, 94(6):1878-1889. 10477716
53. Laemmli UK Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 1970, 227:680-685. 10.1038/227680a0 5432063
54. Chomczynski P Sacchi N Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 1987, 162:156-159. 10.1016/0003-2697(87)90021-2 2440339