In vitro and in vivo evaluation of gellan based ocular inserts of phenylephrine

Acta Pharmaceutica Sciencia

Volumn 49, Issue 1, 2007, Pages 55-63

  Gupta, A ^a   Sharma, S K ^a   Ahuja, M ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Gellan gum; Mydriatic response; Ocular insert; Phenylepherine

Indexed keywords

EYE DROPS; GELLAN; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ARTICLE; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; IN VIVO STUDY; METHODOLOGY; MYDRIASIS; NONHUMAN; RABBIT;

EID: 42449113709     PISSN: 13072080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Balasubramaniam, J., Kumar, M.T., Pandit, J.K. and Kant, S. (2004). Gellan-based scleral implants of indomethacin: in vitro and in vivo evaluation. Drug. Deliv. 11:371-379.
2. Balasubramaniam, J., Kant, S. and Pandit, J.K. (2003). In vitro and in vivo evaluation of the Gelrite gellan gum- based ocular delivery system for indomethacin. Acta Pharm. 53:251-261.
3. Costa., P., Manuel, J. and Lobo, S. (2001). Modeling and comparison of dissolution profiles. Eur. J. Pharm. Sci..13:123-133.
4. Durrani, A.M., Jamshaid, M. and Kellaway, I.W. (1996). A new ocular delivery system for phenylepherine hydrochloride. Arch. Pharm. Res..19:386-389.
5. Hendrickson, R.O. and Hanna, C. (1977). Use of drugs in ointments for routine mydriasis. Ann. Ophthalmol. 9:333-336.
6. Herrero-Vanrell, R., Fernandez-Carballido, A., Frutos, G. and Cadorniga, R. (2000). Enhancement of the mydriatic response to tropicamide by bioadhesive polymers. J. Ocul. Pharmacol. Ther. 16:419-428.
7. Ho, T., Fan, R., Hong, W.W. and Khian, K.B. (1992). Maximal mydriatic evaluation in cataract surgery. J. Cataract Refract. Surg. 18:375-379.
8. Kang, K.S., Veeder, G.T. and Cottrell, I.W. (1983). Gellan gum, a new polysaccharide. Prog. Indust. Microbiol.18:231-253.
9. Korsmeyer, R.W., Gurny, R., Doelker, E., Buri, P. and Peppas, N.A. (1983). Mechanism of solute release from hydrophilic polymers. Int. J. Pharm. 15:25-35.
10. Lee, Y.C., Millard, J.W., Negvesky, G.J., Butrus, S.I. and Yalkowsky, S.H. (1999). Formulation and evaluation of ocular insert containing phenylepherine and tropicamide. Int. J. Pharm. 182:121-126.
11. Mundada, A.S. and Shrikhande, B.K. (2006). Design and evaluation of soluble ocular drug insert for controlled release of ciprofloxacin hydrochloride. Drug Dev. Ind. Pharm. 32:443-448.
12. Rozier, A., Manuel, C., Groove, J. and Plazonet, B. (1989). Gelrite: a novel ion activated in situ gelling polymer for ophthalmic vehicles, Effect on bioavailability of timolol. Int. J. Pharm. 57:163-168.
13. Sasaki, H., Tei, C., Nishida, K. and Nakamura, J. (1993). Drug release from an ophthalmic insert of a beta blocker as an ocular drug delivery system. J. Control. Rel. 27:127-137.
14. Seattone, M.F., Giannaccini, B., Ravecca, S., Marca, F.I. and Tota, G. (1984). Polymeric effects on ocular bioavailability-the influence of different liquid vehicles on the mydriatic response of tropicamide in humans and in rabbits. Int. J. Pharm. 20:187-202.