Significant improvement in extensive lichen sclerosus with tacrolimus ointment and PUVA

American Journal of Clinical Dermatology

Volumn 9, Issue 3, 2008, Pages 175-179

  Valdivielso Ramos, Marta ^a   Bueno, Celso ^b   Hernanz, José Manuel ^b  

^a HOSPITAL UNIVERSITARIO INFANTA LEONOR   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

Lichen sclerosus et atrophicus, treatment; Psoralens, therapeutic use; Tacrolimus, therapeutic use

Indexed keywords

BETAMETHASONE; DEFLAZACORT; POLYPODIUM LEUCOTOMOS EXTRACT; PSORALEN; TACROLIMUS;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; CASE REPORT; CLINICAL ASSESSMENT; CLINICAL EXAMINATION; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HISTOPATHOLOGY; HUMAN; LICHEN SCLEROSUS ET ATROPHICUS; OINTMENT; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PUVA; SKIN BIOPSY; SKIN INFLAMMATION; SKIN MANIFESTATION; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

EID: 42449092823     PISSN: 11750561     EISSN: None     Source Type: Journal    
DOI: 10.2165/00128071-200809030-00006     Document Type: Article

References (44)

1. Meffert J, Davis BM, Grimwood RE. Lichen sclerosus. J Am Acad Dermatol 1995; 32: 393-416
2. Neill SM, Tatnall FM, Cox NH. Guidelines for the management of lichen sclerosus. Br J Dermatol 2002; 147: 640-9
3. Hallopeau H. Leçons cliniques sur les maladées cutanées et syphiliques. Union Med Can 1887; 43: 472
4. Helm KF, Gibson LE, Muller SA. Lichen sclerosus et atrophicus in children and young adults. Pediatr Dermatol 1991; 8: 97-101
5. Vildosola VS, González ME, Campo Virgili ME, et al. Liquen escleroso y atrófico extragenital en una niña prépuber. Actas Dermosifiliogr 1996; 87: 418-20
6. Monteagudo B, Leon E, Lavandeira J, et al. Lichen sclerosus with genital and extragenital lesions. Pediatr Ann 2006; 64: 397-8
7. Röcken M, Ghoreschi K. Morfea y liquen escleroso. In: Bolognia L, Jorizzo JL, Rapini RP, editors. Dermatología. 1st ed. Madrid: Elsevier, 2004: 1503-17
8. Di Silverio A, Serri F. Generalized bullous and haemorrhagic lichen sclerosus et atrophicus. Br J Dermatol 1975; 93: 215-7
9. Wakelin SH, James MP. Extensive lichen sclerosus et atrophicus with bullae and ulceration: improvement with hydroxychloroquine. Clin Exp Dermatol 1994; 19: 332-4
10. Ronnen M, Suster S, Kahana M, et al. Bilateral Koebner phenomenon in lichen sclerosus et atrophicus. Int J Dermatol 1987; 26: 117-8
11. Choi SW, Yang JE, Park HJ, et al. A case of extragenital lichen sclerosus following Blaschko's lines. J Am Acad Dermatol 2000; 43: 903-4
12. Foulds IS. Lichen sclerosus et atrophicus of the scalp. Br J Dermatol 1980; 103: 197-200
13. Purres J, Krull EA. Lichen sclerosus et atrophicus involving the palms. Arch Dermatol 1971; 104: 68-9
14. Kartamaa M, Reitamo S. Treatment of lichen sclerosus with carbon dioxide laser vaporization. Br J Dermatol 1997; 136: 356-9
15. Kreuter A, Jansen T, Stucker M, et al. Low-dose ultraviolet-A1 phototherapy for lichen sclerosus et atrophicus. Clin Exp Dermatol 2001; 26 (1): 30-2
16. Tan SH, Derrick E, McKee PH, et al. Altered p53 expression and epidermal cell proliferation is seen in vulval lichen sclerosus. J Cutan Pathol 1994; 21: 316-23
17. Kreuter A, Gambichler T, Avermaete A, et al. Low-dose ultraviolet-A1 phototherapy for extragenital lichen sclerosus: results of a preliminary study. J Am Acad Dermatol 2002; 46: 251-5
18. Marini A, Blecken S, Ruzicka T, et al. Lichen sclerosus: new aspects of pathogenesis and treatment. Hautarzt 2005; 56: 550-5
19. Meyrick RH, Ridley CM, McGibbon DH, et al. Lichen sclerosus et atrophicus and autoimmunity: a study of 350 women. Br J Dermatol 1988; 118: 41-6
20. Clifton MM, Garner IB, Kohler S, et al. Immunohistochemical evaluation of androgen receptors in genital and extragenital lichen sclerosus: evidence for loss of androgen receptors in lesional epidermis. J Am Acad Dermatol 1999; 41: 43-6
21. Weedon D. Disorders of collagen. In: Weedon D. Skin pathology. 4th ed. Edinburgh: Churchill Livingstone, 2001: 287-315
22. Friedrich EG. Topical testosterone for benign vulvar dystrophy. Obstet Gynecol 1971; 37: 677-86
23. Sideri M, Origoni M, Spinaci L, et al. Topical testosterone in the treatment of vulvar lichen sclerosus. Int J Gynaecol Obstet 1994; 46: 53-6
24. Bousema MT, Romppanen U, Geizer JM, et al. Acitretin in the treatment of lichen sclerosus et atrophicus of the vulva: a double-blind placebo-controlled study. J Am Acad Dermatol 1994; 30: 225-31
25. Penneys NS. Treatment of lichen sclerosus with potassium paraaminobenzoate. J Am Acad Dermatol 1984; 10: 1039-42
26. Brzezinska-Weislo LA, Szeremeta-Bazylewicz GT, Pierzchala EK, et al. Lichen sclerosus et atrophicus: diagnostic and therapeutic difficulties. Wiad Lek 2001; 9-10: 484-91
27. Kreuter A, Gambichler T, Sauermann K, et al. Extragenital lichen sclerosus successfully treated with topical calcipotriol: evaluation by in vivo confocal laser scanning microscopy. Br J Dermatol 2002; 146: 332-3
28. August PJ, Milward TM. Cryosurgery in the treatment of lichen sclerosus et atrophicus of the vulva. Br J Dermatol 1980; 103: 667-70
29. Hillemans P, Untch M, Prove F, et al. Photodynamic therapy of vulvar lichen sclerosus with 5-aminolevulinic acid. Obstet Gynecol 1999; 93: 71-4
30. Greve B, Hartschuh W, Raulin C. Extragenital lichen sclerosus et atrophicus: treatment with pulsed dye laser. Hautarzt 1999; 50: 805-8
31. Boms S, Gambichler T, Freitag M, et al. Pimecrolimus 1% cream for anogenital lichen sclerosus in childhood. BMC Dermatol 2004; 4: 14-7
32. Goldstein AT, Marinoff SC, Christopher K. Pimecrolimus for the treatment of vulvar lichen sclerosus in a premenarchal girl. J Pediatr Adolesc Gynecol 2004; 17: 35-7
33. Bohm M, Frieling U, Luger TA, et al. Successful treatment of anogenital lichen sclerosus with topical tacrolimus. Arch Dermatol 2003; 139: 922-4
34. Kunstfels R, Kirnbauer R, Stingl G, et al. Successful treatment of vulvar lichen sclerosus with topical tacrolimus. Arch Dermatol 2003; 139: 850-2
35. Assmann T, Becker-Wegerich P, Grewe M, et al. Tacrolimus ointment for the treatment of vulvar lichen sclerosus. J Am Acad Dermatol 2003; 48: 935-7
36. Ginarte M, Toribio J. Vulvar lichen sclerosus successfully treated with topical tacrolimus. Eur J Obstet Gynecol Reprod Biol 2005; 123: 123-4
37. Goldstein AT, Marinoff SC, Christopher K. Pimecrolimus for the treatment of vulvar lichen sclerosus: a report of 4 cases. J Reprod Med 2004; 49: 778-80
38. Arican O, Ciralik H, Sasmaz S. Unsuccessful treatment of extragenital lichen sclerosus with topical 1% pimecrolimus cream. J Dermatol 2004; 31: 1014-7
39. Valdivielso-Ramos M, Bueno C. Generalized lichen sclerosus successfully treated with tacrolimus ointment 0.1% [poster no. PO3.57]. 14th EADV Congress; 2005 Oct 12-16; London
40. Breuckmann F, Gambichler T, Altmeyer P, et al. UVA/UVA1 phototherapy and PUVA photochemotherapy in connective tissue diseases and related disorders: a research based review. BMC Dermatol 2004; 20: 4-11
41. Dalmau J, Baselga E, Roe E, et al. Psoralen UVA treatment for generalized prepubertal extragenital lichen sclerosus et atrophicus. J Am Acad Dermatol 2006; 55: S56-8
42. Beattie PE, Dawe RS, Ferguson J, et al. UVA-1 phototherapy for genital lichen sclerosus. Clin Exp Dermatol 2006; 31: 343-7
43. Jubran RF, Dinndorf PA. Successful therapy of refractory graft versus host disease with tacrolimus and psoralen plus ultraviolet light. Ther Drug Monit 1998; 20: 236-9
44. Mehrabi D, Pandya AG. A randomized, placebo-controlled, double-blind trial comparing narrowband UV-B plus 0.1% tacrolimus ointment with narrowband UV-B plus placebo in the treatment of generalized vitiligo. Arch Dermatol 2006; 142: 927-9