-
1
-
-
0038165393
-
A strategy to reduce cardiovascular disease by more than 80%
-
Wald NJ, Law MR: A strategy to reduce cardiovascular disease by more than 80%. BMJ 2003; 326: 1419.
-
(2003)
BMJ
, vol.326
, pp. 1419
-
-
Wald, N.J.1
Law, M.R.2
-
2
-
-
32644457273
-
Exercise rehabilitation in heart disease: The real "polypill" for primary and secondary prevention
-
Piepoli MF: Exercise rehabilitation Tn heart disease: the real "polypill" for primary and secondary prevention. Monaldi Arch Chest Dis 2005; 64: 88-93.
-
(2005)
Monaldi Arch Chest Dis
, vol.64
, pp. 88-93
-
-
Piepoli, M.F.1
-
3
-
-
33745788778
-
Benefits, challenges, and registerability of the polypill
-
Sleight P, Pouleur H, Zannad F: Benefits, challenges, and registerability of the polypill. Eur Heart J 2006; 27: 1651-6.
-
(2006)
Eur Heart J
, vol.27
, pp. 1651-1656
-
-
Sleight, P.1
Pouleur, H.2
Zannad, F.3
-
4
-
-
10844273039
-
The polymeal: A more natural, safer, and probably tastier (than the polypill) strategy to reduce cardiovascular disease by more than 75%
-
Franco OH, Bonneux L, de Laet C, Peeters A, Steyerberg EW, Mackenbach JP: The Aolymeal: a more natural, safer, and probably tastier (than the polypill) strategy to reduce cardiovascular disease by more than 75%. BMJ 2004; 329: 1447-50.
-
(2004)
BMJ
, vol.329
, pp. 1447-1450
-
-
Franco, O.H.1
Bonneux, L.2
de Laet, C.3
Peeters, A.4
Steyerberg, E.W.5
Mackenbach, J.P.6
-
5
-
-
32844474725
-
Polypill strategy vs. prevention clinics for stroke prevention
-
Amarenco P: Polypill strategy vs. prevention clinics for stroke prevention. Cerebrovasc Dis 2006; 21 (Suppl. 1): 35-40.
-
(2006)
Cerebrovasc Dis
, vol.21
, Issue.SUPPL. 1
, pp. 35-40
-
-
Amarenco, P.1
-
7
-
-
33947631906
-
A polypill for secondary prevention: Time to move from intellectual debate to action
-
Fuster V, Sanz G: A polypill foT secondary prevention: time to move from intellectual debate to action. Nat Clin Pract Cardiovasc Med 2007; 4: 173.
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 173
-
-
Fuster, V.1
Sanz, G.2
-
10
-
-
33645113878
-
The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients
-
Ismail R, Teh LK: The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients. J Clin Pharm Ther 2006; 31: 99-109.
-
(2006)
J Clin Pharm Ther
, vol.31
, pp. 99-109
-
-
Ismail, R.1
Teh, L.K.2
-
11
-
-
0029028932
-
Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
-
Bertilsson L: Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995; 29: 192-209.
-
(1995)
Clin Pharmacokinet
, vol.29
, pp. 192-209
-
-
Bertilsson, L.1
-
12
-
-
20244366089
-
Cytochrome p450 polymorphisms in geriatric patients: Impact on adverse drug reactions - A pilot study
-
Egger T, Dormann H, Ahne G et al. Cytochrome p450 polymorphisms in geriatric patients: Impact on adverse drug reactions - a pilot study. Drugs Aging 2005; 22: 265-72.
-
(2005)
Drugs Aging
, vol.22
, pp. 265-272
-
-
Egger, T.1
Dormann, H.2
Ahne, G.3
-
13
-
-
0017084595
-
Pharmacokinetics of propranolol: A review
-
Shand DG: Pharmacokinetics Af propranolol: a review. Postgrad Med J 1976; 52 (Suppl. 4): 22-5.
-
(1976)
Postgrad Med J
, vol.52
, Issue.SUPPL. 4
, pp. 22-25
-
-
Shand, D.G.1
-
14
-
-
34249824591
-
Pharmacogenetics of beta-blockers
-
Shin J, Johnson JA: Pharmacogenetics of beta-blockers. Pharmacotherapy 2007; 27: 874-87.
-
(2007)
Pharmacotherapy
, vol.27
, pp. 874-887
-
-
Shin, J.1
Johnson, J.A.2
-
15
-
-
0017643396
-
Antihypertensive and biochemical effects of chlorthalidone
-
Tweeddale MG, Ogilvie RI, Ruedy J: Antihypertensive and biochemical effects of chlorthalidone. Clin Pharmacol Ther 1977; 22: 519-27.
-
(1977)
Clin Pharmacol Ther
, vol.22
, pp. 519-527
-
-
Tweeddale, M.G.1
Ogilvie, R.I.2
Ruedy, J.3
-
16
-
-
0021123904
-
Intracellular magnesium loss after diuretic administration
-
Dyckner T, Wester PO: Intracellular magnesium loss after diuretic administration. Drugs 1984; 28: 161-6.
-
(1984)
Drugs
, vol.28
, pp. 161-166
-
-
Dyckner, T.1
Wester, P.O.2
-
17
-
-
0024584277
-
Diagnosis of sulfonamide hypersensitivity reactions by in-vitro 'rechallenge' with hydroxlamine metabolites
-
Rieder MJ, Uetrecht J, Shear NH, Cannon M, Miller M, Spielberg SP: Diagnosis of sulfonamide hypersensitivity reactions by in-vitro 'rechallenge' with hydroxlamine metabolites. Ann Intern Med 1989; 110: 286-9.
-
(1989)
Ann Intern Med
, vol.110
, pp. 286-289
-
-
Rieder, M.J.1
Uetrecht, J.2
Shear, N.H.3
Cannon, M.4
Miller, M.5
Spielberg, S.P.6
-
18
-
-
33745576877
-
Effect of angiotensin II type 1 receptor antagonism on endothelial function: Role of bradykinin and nitric oxide
-
Landmesser U, Drexler H: Effect of angiotensin II type 1 receptor antagonism on endothelial function: Role of bradykinin and nitric oxide. J Hypertens (Suppl.) 2006; 24: S39-43.
-
(2006)
J Hypertens (Suppl.)
, vol.24
-
-
Landmesser, U.1
Drexler, H.2
-
19
-
-
0345008869
-
Serum metabolism of bradykinin and des-Arg9-bradykinin in patients with angiotensin-converting enzyme inhibitor-associated angioedema
-
Blais C Jr., Rouleau JL, Brown NJ et al. Serum metabolism of bradykinin and des-Arg9-bradykinin in patients with angiotensin-converting enzyme inhibitor-associated angioedema. Immunopharmacology 1999; 43: 293-302.
-
(1999)
Immunopharmacology
, vol.43
, pp. 293-302
-
-
Blais, C.1
Rouleau, J.L.2
Brown, N.J.3
-
20
-
-
33845354316
-
Myotoxicity associated with lipid-lowering drugs
-
Baer AN, Wortmann RL: Myotoxicity associated with lipid-lowering drugs. Curr Opin Rheumatol 2007; 19: 67-73.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 67-73
-
-
Baer, A.N.1
Wortmann, R.L.2
-
21
-
-
33746665298
-
Genetic risk factors associated with lipid-lowering drug-induced myopathies
-
Vladutiu GD, Simmons Z, Isackson PJ et al. Genetic risk factors associated with lipid-lowering drug-induced myopathies. Muscle Nerve 2006; 34: 153-62.
-
(2006)
Muscle Nerve
, vol.34
, pp. 153-162
-
-
Vladutiu, G.D.1
Simmons, Z.2
Isackson, P.J.3
-
22
-
-
34247639532
-
Effect of coenzyme q10 on myopathic symptoms in patients treated with statins
-
Caso G, Kelly P, McNurlan MA, Lawson WE: Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol 2007; 99: 1409-12.
-
(2007)
Am J Cardiol
, vol.99
, pp. 1409-1412
-
-
Caso, G.1
Kelly, P.2
McNurlan, M.A.3
Lawson, W.E.4
-
23
-
-
4644256971
-
Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: Efficacy and safety of ezetimibe co-administered with atorvastatin
-
Stein E, Stender S, Mata P et al. Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: Efficacy and safety of ezetimibe co-administered with atorvastatin. Am Heart J 2004; 148: 447-55.
-
(2004)
Am Heart J
, vol.148
, pp. 447-455
-
-
Stein, E.1
Stender, S.2
Mata, P.3
-
24
-
-
0031954328
-
Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid
-
Kantola T, Kivisto KT, Neuvonen PJ: Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1998; 63: 397-402.
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 397-402
-
-
Kantola, T.1
Kivisto, K.T.2
Neuvonen, P.J.3
-
25
-
-
3142523464
-
Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin
-
Lilja JJ, Neuvonen M, Neuvonen PJ: Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin. Br J Clin Pharmacol 2004; 58: 56-60.
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 56-60
-
-
Lilja, J.J.1
Neuvonen, M.2
Neuvonen, P.J.3
-
26
-
-
0033972441
-
Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition
-
Dresser GK, Spence JD, Bailey DG: Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition. Clin Pharmacokinet 2000; 38: 41-57.
-
(2000)
Clin Pharmacokinet
, vol.38
, pp. 41-57
-
-
Dresser, G.K.1
Spence, J.D.2
Bailey, D.G.3
-
27
-
-
0242645646
-
Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
-
Lilja JJ, Kivisto KT, Neuvonen PJ: Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999; 66: 118-27.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 118-127
-
-
Lilja, J.J.1
Kivisto, K.T.2
Neuvonen, P.J.3
-
28
-
-
0038441818
-
Simvastatin-fluconazole causing rhabdomyolysis
-
Shaukat A, Benekli M, Vladutiu GD, Slack JL, Wetzler M, Baer MR: Simvastatin-fluconazole causing rhabdomyolysis. Ann Pharmacother 2003; 37: 1032-5.
-
(2003)
Ann Pharmacother
, vol.37
, pp. 1032-1035
-
-
Shaukat, A.1
Benekli, M.2
Vladutiu, G.D.3
Slack, J.L.4
Wetzler, M.5
Baer, M.R.6
-
29
-
-
1342330817
-
Statin-associated rhabdomyolysis triggered by grapefruit consumption
-
Dreier JP, Endres M: Statin-associated rhabdomyolysis triggered by grapefruit consumption. Neurology 2004; 62: 670.
-
(2004)
Neurology
, vol.62
, pp. 670
-
-
Dreier, J.P.1
Endres, M.2
-
30
-
-
0030944304
-
Drug interactions with grapefruit: Whose responsibility is it to warn the public?
-
[see comments]
-
Spence JD: Drug interactions With grapefruit: whose responsibility is it to warn the public? [see comments]. Clin Pharmacol Ther 1997; 61: 395-400.
-
(1997)
Clin Pharmacol Ther
, vol.61
, pp. 395-400
-
-
Spence, J.D.1
-
31
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease
-
Graham IM, Daly L, Refsum H et al. Plasma homocysteine as a risk factor for vascular disease. JAMA 1997; 277: 1775-81.
-
(1997)
JAMA
, vol.277
, pp. 1775-1781
-
-
Graham, I.M.1
Daly, L.2
Refsum, H.3
-
32
-
-
1842370239
-
Plasma homocysteine levels and mortality in patients with coronary artery disease
-
Nygård O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, Vollset SE: Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 1997; 337: 230-6.
-
(1997)
N Engl J Med
, vol.337
, pp. 230-236
-
-
Nygård, O.1
Nordrehaug, J.E.2
Refsum, H.3
Ueland, P.M.4
Farstad, M.5
Vollset, S.E.6
-
33
-
-
33646765431
-
The Hordaland homocysteine study: A community-based study of homocysteine, its determinants, and associations with disease
-
Refsum H, Nurk E, Smith AD et al. The Hordaland homocysteine study: A community-based study of homocysteine, its determinants, and associations with disease. J Nutr 2006; 136: 1731S-40S.
-
(2006)
J Nutr
, vol.136
-
-
Refsum, H.1
Nurk, E.2
Smith, A.D.3
-
34
-
-
34547743420
-
Homocysteine-lowering therapy: A role in stroke prevention?
-
Spence JD: Homocysteine-lAwering therapy: a role in stroke prevention? Lancet Neurol 2007; 6: 830-8.
-
(2007)
Lancet Neurol
, vol.6
, pp. 830-838
-
-
Spence, J.D.1
-
35
-
-
34249730020
-
Efficacy of folic acid supplementation in stroke prevention: A meta-analysis
-
Wang X, Qin X, Li H et al. Efficacy of folic acid supplementation in stroke prevention: A meta-analysis. Lancet 2007; 369: 1876-82.
-
(2007)
Lancet
, vol.369
, pp. 1876-1882
-
-
Wang, X.1
Qin, X.2
Li, H.3
-
36
-
-
2242477014
-
Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials
-
Homocysteine Lowering Trialists' Collaboration
-
Homocysteine Lowering Trialists' Collaboration. Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials. BMJ 1998; 316: 894-8.
-
(1998)
BMJ
, vol.316
, pp. 894-898
-
-
-
37
-
-
20544474458
-
Increased importance of Vitamin B12 for total homocysteine and carotid plaque in the era of folate fortification of the grain supply
-
Robertson J, Iemolo F, Stabler SP, Allen RH, Spence JD: Increased importance of Vitamin B12 for total homocysteine and carotid plaque in the era of folate fortification of the grain supply. CMAJ 2005; 172: 1569-73.
-
(2005)
CMAJ
, vol.172
, pp. 1569-1573
-
-
Robertson, J.1
Iemolo, F.2
Stabler, S.P.3
Allen, R.H.4
Spence, J.D.5
-
38
-
-
0037132839
-
Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease
-
Quinlivan EP, McPartlin J, McNulty H et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet 2002; 359: 227-8.
-
(2002)
Lancet
, vol.359
, pp. 227-228
-
-
Quinlivan, E.P.1
McPartlin, J.2
McNulty, H.3
-
39
-
-
0033551352
-
The effect of folic acid fortification on plasma folate and total homocysteine concentrations
-
Jacques PF, Selhub J, Bostom AG, Wilson PW, Rosenberg IH: The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med 1999; 340: 1449-54.
-
(1999)
N Engl J Med
, vol.340
, pp. 1449-1454
-
-
Jacques, P.F.1
Selhub, J.2
Bostom, A.G.3
Wilson, P.W.4
Rosenberg, I.H.5
-
40
-
-
4043175633
-
Vitamin B12 (cobalamin) deficiency in elderly patients
-
Andres E, Loukili NH, Noel E et al. Vitamin B12 (cobalamin) deficiency in elderly patients. CMAJ 2004; 171: 251-9.
-
(2004)
CMAJ
, vol.171
, pp. 251-259
-
-
Andres, E.1
Loukili, N.H.2
Noel, E.3
-
41
-
-
33748361787
-
Nutrition and stroke prevention
-
Spence JD: Nutrition and stroke prevention. Stroke 2006; 37: 2430-5.
-
(2006)
Stroke
, vol.37
, pp. 2430-2435
-
-
Spence, J.D.1
-
42
-
-
0036843983
-
Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults
-
Rajan S, Wallace JI, Brodkin KI, Beresford SA, Allen RH, Stabler SP: Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults. J Am Geriatr Soc 2002; 50: 1789-95.
-
(2002)
J Am Geriatr Soc
, vol.50
, pp. 1789-1795
-
-
Rajan, S.1
Wallace, J.I.2
Brodkin, K.I.3
Beresford, S.A.4
Allen, R.H.5
Stabler, S.P.6
-
43
-
-
33645753544
-
Homocysteine lowering with folic acid and B vitamins in vascular disease
-
Lonn E, Yusuf S, Arnold MJ et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006; 354: 1567-77.
-
(2006)
N Engl J Med
, vol.354
, pp. 1567-1577
-
-
Lonn, E.1
Yusuf, S.2
Arnold, M.J.3
-
44
-
-
34547743420
-
Homocysteine-lowering therapy: A role in stroke prevention?
-
Spence JD: Homocysteine-lAwering therapy: a role in stroke prevention? Lancet Neurol 2007; 7: 830-8.
-
(2007)
Lancet Neurol
, vol.7
, pp. 830-838
-
-
Spence, J.D.1
-
45
-
-
33745685204
-
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy
-
Khan NA, McAlister FA, Rabkin SW et al. The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - therapy. Can J Cardiol 2006; 22: 583-93.
-
(2006)
Can J Cardiol
, vol.22
, pp. 583-593
-
-
Khan, N.A.1
McAlister, F.A.2
Rabkin, S.W.3
-
46
-
-
0036314225
-
Amiloride, a specific drug for hypertension in black people with T594M variant? Hypertension
-
Baker EH, Duggal A, Dong Y et al. Amiloride, a specific drug for hypertension in black people with T594M variant? Hypertension. Hypertension 2002; 40: 13-7.
-
(2002)
Hypertension
, vol.40
, pp. 13-17
-
-
Baker, E.H.1
Duggal, A.2
Dong, Y.3
-
47
-
-
0035057456
-
Screening for primary aldosteronism without discontinuing hypertensive medications: Plasma aldosterone-renin ratio
-
Gallay BJ, Ahmad S, Xu L, Toivola B, Davidson RC: Screening for primary aldosteronism without discontinuing hypertensive medications: Plasma aldosterone-renin ratio. Am J Kidney Dis 2001; 37: 699-705.
-
(2001)
Am J Kidney Dis
, vol.37
, pp. 699-705
-
-
Gallay, B.J.1
Ahmad, S.2
Xu, L.3
Toivola, B.4
Davidson, R.C.5
-
48
-
-
0021737585
-
Primary aldosteronism is composed of primary adrenal hyperplasia and adenoma
-
Biglieri EG, Kater CE, Arteaga EE: Primary aldosteronism is composed of primary adrenal hyperplasia and adenoma. J Hypertens 1984; 2: S259-61.
-
(1984)
J Hypertens
, vol.2
-
-
Biglieri, E.G.1
Kater, C.E.2
Arteaga, E.E.3
-
49
-
-
0016423806
-
Stimulated renin: A screening test for hypertension
-
Wallach L, NAarai I, Dawson KG: Stimulated renin: a screening test for hypertension. Ann Intern Med 1975; 82: 27-34.
-
(1975)
Ann Intern Med
, vol.82
, pp. 27-34
-
-
Wallach, L.1
Nyarai, I.2
Dawson, K.G.3
-
50
-
-
0032737636
-
Physiologic tailoring of therapy for resistant hypertension: 20 year' experience with stimulated renin profiling
-
Spence JD: Physiologic tailoring of therapy for resistant hypertension: 20 year' experience with stimulated renin profiling. Am J Hypertens 1999; 12: 1077-83.
-
(1999)
Am J Hypertens
, vol.12
, pp. 1077-1083
-
-
Spence, J.D.1
-
51
-
-
0842331433
-
Genetic variation in the epithelial sodium channel: A risk factor for hypertension in people of African origin
-
Swift PA, MacGregor GA: Genetic variation in the epithelial sodium channel: A risk factor for hypertension in people of African origin. Adv Ren Replace Ther 2004; 11: 76-86.
-
(2004)
Adv Ren Replace Ther
, vol.11
, pp. 76-86
-
-
Swift, P.A.1
MacGregor, G.A.2
-
52
-
-
34249775519
-
Combining multiple approaches for the secondary prevention of vascular events after stroke. A quantitative modeling study
-
Hackam DG, Spence JD: Combining multiple approaches for the secondary prevention of vascular events after stroke. A quantitative modeling study. Stroke 2007; 38: 1881-5.
-
(2007)
Stroke
, vol.38
, pp. 1881-1885
-
-
Hackam, D.G.1
Spence, J.D.2
|