Study on the expression of survivin mRNA and protein in nasopharyngeal carcinoma

Chinese Journal of Medical Genetics

Volumn 25, Issue 2, 2008, Pages 179-182

  Fu, Sheng Miao ^a,b   Wang, Yu Tian ^b   Tu, Zhi Hua ^b   Deng, Li Qun ^b   Liang, Zhu ^b   Lin, Zhen Qun ^b   Cai, Jun Hong ^b   Gong, Xuan Ju ^b  

^a HAINAN MEDICAL UNIVERSITY   (China)

^b HAINAN PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Immunohistochemical staining; In situ hybridization; Nasopharyngeal carcinoma; Survivin gene

Indexed keywords

MESSENGER RNA; SURVIVIN;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CHI SQUARE TEST; CORRELATION ANALYSIS; FEMALE; GENDER; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RHINOPHARYNGITIS; STATISTICAL SIGNIFICANCE;

ADULT; AGE FACTORS; AGED; CARCINOMA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; SEX FACTORS; YOUNG ADULT;

EID: 42249107003     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Lo Muzio L, Pannone G, Staibano S, et al. Survivin expression in oral squamous carcinoma. Br J Cancer, 2003, 89:2244-2248.
2. Zhang S, Xiao JY, Tian YQ, et al. Overexpression of survivin protein in nasopharyngeal carcinoma: correlation with apoptosis index and the prognosis. Chin J Otorhinolaryngol Skull Base Surg, 2004, 10:197.
3. Ambrosini G, Adida C, Altieri DC. Anovel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med, 1997, 3:917-921.
4. Suzuki A, Ito T, Kawano H, et al. Survivin initiates procaspase 3/p21 complex formation as a result of interaction with CDK4 to resist Fas-mediated cell death. Oncogene, 2000, 19:1346-1353.
5. Vong QP, Cao K, Li HY, et al. Chromosome alignment and segregation regulated by ubiquitination of survivin. Science, 2005, 310:1498-1504.
6. Du C, Fang M, Li Y, et al. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell, 2000, 102:33-42.
7. Olie RA, Simões-Wüst AP, Baumann B, et al. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res, 2000, 60:2805-2809.
8. Smith SD, Wheekr MA, Pkscia J, et al. Urine detection of survivin and diagnosis of bladder cancer. JAMA, 2001, 285:324-328.
9. Li CH, Ma ZS, Xiao G, et al. Expression of apoptosis inhibitor survivin in laryngeal carcinoma cells and clinical significance of expressed product. Chin J Biol, 2004, 17:110-121.
10. Krambeck AE, Dong H, Thompson RH, et al. Survivin and B7-H1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma. Clin Cancer Res, 2007, 13: 1749-1756.
11. Zheng JF, He YP, Shen HR, et al. Expression and clinical significance of apoptosis inhibitor survivin in nasopharyngeal carcinoma. Chin J Cancer Prev Treat, 2006, 13:426-429.
12. Jiang WZ, Lu JS, Wen JF, et al. Clinical value of nm23-H1 and survivin protein expression in nasopharyngeal carcinoma. Chin J Radiat Oncol, 2005, 14:383-387.
13. Xiang Q, Zeng SE, Liu Q, et al. The expression of survivin and Bcl-2 are associated with nasopharyngeal carcinoma. Carcinogenests · Teratogesis · Mutagenesis, 2006, 4:384-386.
14. Dong Y, Sui L, Watanabe Y, et al. survivin expression in laryngeal squamous cell and its prognostic implication. Anticancer Res, 2002, 22:2377-2383.