Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15

Experimental Hematology

Volumn 36, Issue 5, 2008, Pages 598-608

  McCullar, Valarie ^a   Oostendorp, Robert ^b   Panoskaltsis Mortari, Angela ^a   Yun, Gong ^a   Lutz, Charles T ^c   Wagner, John E ^a   Miller, Jeffrey S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD56 ANTIGEN; CD7 ANTIGEN; CD94 ANTIGEN; FLT3 LIGAND; INTERLEUKIN 15; INTERLEUKIN 3; PROTEIN KIR; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CELL LINE; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO CELL; FETUS CELL; HUMAN; HUMAN CELL; LIVER CELL; MICROENVIRONMENT; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; STROMA CELL; UMBILICAL CORD BLOOD;

ANIMALS; ANTIGENS, CD56; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-15; INTERLEUKIN-3; KILLER CELLS, NATURAL; LIVER; MEMBRANE PROTEINS; MICE; RECEPTORS, KIR; STROMAL CELLS;

MURINAE;

EID: 42249106031     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2008.01.001     Document Type: Article

References (55)

1. Leibson P.J. Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity 6 (1997) 655-661
2. Leibson P. Viewpoint: signal transduction during natural killer cell activation. Nat Immun 14 (1995) 117-122
3. Lanier L.L., Corliss B., and Phillips J.H. Arousal and inhibition of human NK cells. Immunol Rev 155 (1997) 145-154
4. Raulet D.H., and Held W. Natural killer cell receptors: the offs and ons of NK cell recognition. Cell 82 (1995) 697-700
5. Miller J.S., Oelkers S., Verfaillie C., and McGlave P. Role of monocytes in the expansion of human activated natural killer cells. Blood 80 (1992) 2221-2229
6. Miller J.S., Verfaillie C., and McGlave P. The generation of human natural killer cells from CD34+/DR- primitive progenitors in long-term bone marrow culture. Blood 80 (1992) 2182-2187
7. Silva M.R., Hoffman R., Srour E.F., and Ascensao J.L. Generation of human natural killer cells from immature progenitors does not require marrow stromal cells. Blood 84 (1994) 841-846
8. Lotzova E., Savary C.A., and Champlin R.E. Genesis of human oncolytic natural killer cells from primitive CD34+CD33- bone marrow progenitors. J Immunol 150 (1993) 5263-5269
9. Srour E.F., Zanjani E.D., Cornetta K., et al. Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep. Blood 82 (1993) 3333-3342
10. Nagler A., Lanier L.L., Cwirla S., and Phillips J.H. Comparative studies of human FcRIII-positive and negative natural killer cells. J Immunol 143 (1989) 3183-3191
11. Nagler A., Lanier L.L., and Phillips J.H. Constitutive expression of high affinity interleukin 2 receptors on human CD16-natural killer cells in vivo. J Exp Med 171 (1990) 1527-1533
12. Pierson B.A., Gupta K., Hu W.S., and Miller J.S. Human natural killer cell expansion is regulated by thrombospondin-mediated activation of transforming growth factor-beta 1 and independent accessory cell-derived contact and soluble factors. Blood 87 (1996) 180-189
13. Pierson B.A., and Miller J.S. CD56+bright and CD56+dim natural killer cells in patients with chronic myelogenous leukemia progressively decrease in number, respond less to stimuli that recruit clonogenic natural killer cells, and exhibit decreased proliferation on a per cell basis. Blood 88 (1996) 2279-2287
14. Matos M.E., Schnier G.S., Beecher M.S., Ashman L.K., William D.E., and Caligiuri M.A. Expression of a functional c-kit receptor on a subset of natural killer cells. J Exp Med 178 (1993) 1079-1084
15. Carson W.E., Haldar S., Baiocchi R.A., Croce C.M., and Caligiuri M.A. The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc Natl Acad Sci U S A 91 (1994) 7553-7557
16. Hurley R.W., McCarthy J.B., and Verfaillie C.M. Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest 96 (1995) 511-519
17. Verfaillie C.M. Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis. Blood 79 (1992) 2821-2826
18. Ogasawara K., Hida S., Azimi N., et al. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 391 (1998) 700-703
19. Kennedy M.K., Glaccum M., Brown S.N., et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 191 (2000) 771-780
20. Lodolce J.P., Boone D.L., Chai S., et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9 (1998) 669-676
21. Mrozek E., Anderson P., and Caligiuri M.A. Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. Blood 87 (1996) 2632-2640
22. Carson W.E., Fehniger T.A., Haldar S., et al. A potential role for interleukin-15 in the regulation of human natural killer cell survival. J Clin Invest 99 (1997) 937-943
23. Cooper M.A., Bush J.E., Fehniger T.A., et al. In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood 100 (2002) 3633-3638
24. Prlic M., Blazar B.R., Farrar M.A., and Jameson S.C. In vivo survival and homeostatic proliferation of natural killer cells. J Exp Med 197 (2003) 967-976
25. Miller J.S., McCullar V., Punzel M., Lemischka I.R., and Moore K.A. Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells. Blood 93 (1999) 96-106
26. Oostendorp R.A., Harvey K.N., Kusadasi N., et al. Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood 99 (2002) 1183-1189
27. Oostendorp R.A., Medvinsky A.J., Kusadasi N., et al. Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis. J Cell Sci 115 (2002) 2099-2108
28. Gravisaco M.J., Mongini C., Alvarez E., et al. IL-2, IL-10, IL-15 and TNF are key regulators of murine T-cell lymphoma growth. Int J Mol Med 12 (2003) 627-632
29. Pribyl J.R., Dittel B.N., and LeBien T.W. In vitro studies of human B lymphopoiesis. Ann N Y Acad Sci 764 (1995) 9-18
30. Miller J.S., Alley K.A., and McGlave P. Differentiation of natural killer (NK) cells from human primitive marrow progenitors in a stroma-based long-term culture system: identification of a CD34+7+ NK progenitor. Blood 83 (1994) 2594-2601
31. Yu H., Fehniger T.A., Fuchshuber P., et al. Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15. Blood 92 (1998) 3647-3657
32. Galy A., Travis M., Cen D., and Chen B. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 3 (1995) 459-473
33. Kouro T., Medina K.L., Oritani K., and Kincade P.W. Characteristics of early murine B-lymphocyte precursors and their direct sensitivity to negative regulators. Blood 97 (2001) 2708-2715
34. Loza M.J., and Perussia B. Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation?. Nat Immunol 2 (2001) 917-924
35. Gaddy J., and Broxmeyer H.E. Cord blood CD16+56- cells with low lytic activity are possible precursors of mature natural killer cells. Cell Immunol 180 (1997) 132-142
36. Mavilio D., Lombardo G., Benjamin J., et al. Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals. Proc Natl Acad Sci U S A 102 (2005) 2886-2891
37. Yu J., Heller G., Chewning J., Kim S., Yokoyama W.M., and Hsu K.C. Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands. J Immunol 179 (2007) 5977-5989
38. Kim S., Poursine-Laurent J., Truscott S.M., et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436 (2005) 709-713
39. Saleh A., Davies G.E., Pascal V., et al. Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation. Immunity 21 (2004) 55-66
40. Anderson S.K. Transcriptional regulation of NK cell receptors. Curr Top Microbiol Immunol 298 (2006) 59-75
41. Dubois S., Mariner J., Waldmann T.A., and Tagaya Y. IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity 17 (2002) 537-547
42. Giron-Michel J., Giuliani M., Fogli M., et al. Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors. Blood 106 (2005) 2302-2310
43. Burkett P.R., Koka R., Chien M., Chai S., Boone D.L., and Ma A. Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis. J Exp Med 200 (2004) 825-834
44. Lucas M., Schachterle W., Oberle K., Aichele P., and Diefenbach A. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 26 (2007) 503-517
45. Schluns K.S., Nowak E.C., Cabrera-Hernandez A., Puddington L., Lefrancois L., and Aguila H.L. Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression. Proc Natl Acad Sci U S A 101 (2004) 5616-5621
46. Freud A.G., Becknell B., Roychowdhury S., et al. A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells. Immunity 22 (2005) 295-304
47. Freud A.G., Yokohama A., Becknell B., et al. Evidence for discrete stages of human natural killer cell differentiation in vivo. J Exp Med 203 (2006) 1033-1043
48. Miller J.S., and McCullar V. Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2. Blood 98 (2001) 705-713
49. Medvinsky A., and Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86 (1996) 897-906
50. Moore K.A., Ema H., and Lemischka I.R. In vitro maintenance of highly purified, transplantable hematopoietic stem cells. Blood 89 (1997) 4337-4347
51. Dennis J.E., and Charbord P. Origin and differentiation of human and murine stroma. Stem Cells 20 (2002) 205-214
52. Oostendorp R.A., Robin C., Steinhoff C., et al. Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures. Stem Cells 23 (2005) 842-851
53. Calvi L.M., Adams G.B., Weibrecht K.W., et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425 (2003) 841-846
54. Kusadasi N., Oostendorp R.A., Koevoet W.J., Dzierzak E.A., and Ploemacher R.E. Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFC(week6) in extended long-term cultures. Leukemia 16 (2002) 1782-1790
55. Miller J.S., Soignier Y., Panoskaltsis-Mortari A., et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 105 (2005) 3051-3057