메뉴 건너뛰기




Volumn 27, Issue 18, 2008, Pages 2594-2601

Thrombin cleaves the high molecular weight forms of basic fibroblast growth factor (FGF-2): A novel mechanism for the control of FGF-2 and thrombin activity

Author keywords

Endothelial cells; Inflammation; Migration; Proliferation; Proteolysis; Serine proteinases

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; THROMBIN;

EID: 42249099989     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210899     Document Type: Article
Times cited : (17)

References (40)
  • 1
    • 14044278145 scopus 로고    scopus 로고
    • Proteolysis of non-phosphorylated and phosphorylated tau by thrombin
    • Arai T, Guo JP, McGeer PL. (2005). Proteolysis of non-phosphorylated and phosphorylated tau by thrombin. J Biol Chem 280: 5145-5153.
    • (2005) J Biol Chem , vol.280 , pp. 5145-5153
    • Arai, T.1    Guo, J.P.2    McGeer, P.L.3
  • 3
    • 0028939683 scopus 로고
    • Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: Possible intracellular signaling by the high molecular weight forms
    • Bikfalvi A, Klein S, Pintucci G, Quarto N, Mignatti P, Rifkin DB. (1995). Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms. J Cell Biol 129: 233-243.
    • (1995) J Cell Biol , vol.129 , pp. 233-243
    • Bikfalvi, A.1    Klein, S.2    Pintucci, G.3    Quarto, N.4    Mignatti, P.5    Rifkin, D.B.6
  • 4
    • 0026112389 scopus 로고
    • Direct evidence for methylation of arginine residues in high molecular weight forms of basic fibroblast growth factor
    • Burgess WH, Bizik J, Mehlman T, Quarto N, Rifkin DB. (1991). Direct evidence for methylation of arginine residues in high molecular weight forms of basic fibroblast growth factor. Cell Regul 2: 87-93.
    • (1991) Cell Regul , vol.2 , pp. 87-93
    • Burgess, W.H.1    Bizik, J.2    Mehlman, T.3    Quarto, N.4    Rifkin, D.B.5
  • 5
    • 1842685408 scopus 로고    scopus 로고
    • Expression of the fibroblast growth factor-2 isoforms and the FGF receptor 1-4 transcripts in the rat model system of Parkinson's disease
    • Claus P, Werner S, Timmer M, Grothe C. (2004). Expression of the fibroblast growth factor-2 isoforms and the FGF receptor 1-4 transcripts in the rat model system of Parkinson's disease. Neurosci Lett 360: 117-120.
    • (2004) Neurosci Lett , vol.360 , pp. 117-120
    • Claus, P.1    Werner, S.2    Timmer, M.3    Grothe, C.4
  • 6
    • 28344436780 scopus 로고    scopus 로고
    • Protease-activated receptors in hemostasis, thrombosis and vascular biology
    • Coughlin SR. (2005). Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost 3: 1800-1814.
    • (2005) J Thromb Haemost , vol.3 , pp. 1800-1814
    • Coughlin, S.R.1
  • 7
    • 0032485416 scopus 로고    scopus 로고
    • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
    • Counter CM, Meyerson M, Eaton EN, Ellisen LW, Caddle SD, Haber DA et al. (1998). Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene 16: 1217-1222.
    • (1998) Oncogene , vol.16 , pp. 1217-1222
    • Counter, C.M.1    Meyerson, M.2    Eaton, E.N.3    Ellisen, L.W.4    Caddle, S.D.5    Haber, D.A.6
  • 8
    • 0036181736 scopus 로고    scopus 로고
    • Autocrine production of basic fibroblast growth factor translated from novel synthesized mRNA mediates thrombin-induced mitogenesis in smooth muscle cells
    • Cucina A, Borrelli V, Lucarelli M, Sterpetti AV, Cavallaro A, Strom R et al. (2002). Autocrine production of basic fibroblast growth factor translated from novel synthesized mRNA mediates thrombin-induced mitogenesis in smooth muscle cells. Cell Biochem Funct 20: 39-46.
    • (2002) Cell Biochem Funct , vol.20 , pp. 39-46
    • Cucina, A.1    Borrelli, V.2    Lucarelli, M.3    Sterpetti, A.V.4    Cavallaro, A.5    Strom, R.6
  • 9
    • 0023001143 scopus 로고
    • Thrombin stimulates c-sis gene expression in microvascular endothelial cells
    • Daniel TO, Gibbs VC, Milfay DF, Garovoy MR, Williams LT. (1986). Thrombin stimulates c-sis gene expression in microvascular endothelial cells. J Biol Chem 261: 9579-9582.
    • (1986) J Biol Chem , vol.261 , pp. 9579-9582
    • Daniel, T.O.1    Gibbs, V.C.2    Milfay, D.F.3    Garovoy, M.R.4    Williams, L.T.5
  • 10
    • 0037163024 scopus 로고    scopus 로고
    • Inhibition of cell migration and angiogenesis by the amino-terminal fragment of 24kD basic fibroblast growth factor
    • Ding L, Donate F, Parry GC, Guan X, Maher P, Levin EG. (2002). Inhibition of cell migration and angiogenesis by the amino-terminal fragment of 24kD basic fibroblast growth factor. J Biol Chem 277: 31056-31061.
    • (2002) J Biol Chem , vol.277 , pp. 31056-31061
    • Ding, L.1    Donate, F.2    Parry, G.C.3    Guan, X.4    Maher, P.5    Levin, E.G.6
  • 11
    • 0031927754 scopus 로고    scopus 로고
    • Thrombin receptor overexpression in malignant and physiological invasion processes
    • Even-Ram S, Uziely B, Cohen P, Grisaru-Granovsky S, Maoz M, Ginzburg Y et al. (1998). Thrombin receptor overexpression in malignant and physiological invasion processes. Nat Med 4: 909-914.
    • (1998) Nat Med , vol.4 , pp. 909-914
    • Even-Ram, S.1    Uziely, B.2    Cohen, P.3    Grisaru-Granovsky, S.4    Maoz, M.5    Ginzburg, Y.6
  • 13
    • 0008563256 scopus 로고
    • Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons
    • Florkiewicz RZ, Sommer A. (1989). Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons. Proc Natl Acad Sci USA 86: 3978-3981.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3978-3981
    • Florkiewicz, R.Z.1    Sommer, A.2
  • 14
    • 0028027007 scopus 로고
    • Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway
    • Herbert JM, Dupuy E, Laplace MC, Zini JM, Bar Shavit R, Tobelem G. (1994). Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway. Biochem J 303(Part 1): 227-231.
    • (1994) Biochem J , vol.303 , Issue.PART 1 , pp. 227-231
    • Herbert, J.M.1    Dupuy, E.2    Laplace, M.C.3    Zini, J.M.4    Bar Shavit, R.5    Tobelem, G.6
  • 16
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. (2004). Evolution of the Fgf and Fgfr gene families. Trends Genet 20: 563-569.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 17
    • 0029787831 scopus 로고    scopus 로고
    • Integrin regulation by endogenous expression of 18-kDa fibroblast growth factor-2
    • Klein S, Bikfalvi A, Birkenmeier TM, Giancotti FG, Rifkin DB. (1996). Integrin regulation by endogenous expression of 18-kDa fibroblast growth factor-2. J Biol Chem 271: 22583-22590.
    • (1996) J Biol Chem , vol.271 , pp. 22583-22590
    • Klein, S.1    Bikfalvi, A.2    Birkenmeier, T.M.3    Giancotti, F.G.4    Rifkin, D.B.5
  • 18
    • 0034603168 scopus 로고    scopus 로고
    • Biochemical analysis of the arginine methylation of high molecular weight fibroblast growth factor-2
    • Klein S, Carroll JA, Chen Y, Henry MF, Henry PA, Ortonowski IE et al. (2000). Biochemical analysis of the arginine methylation of high molecular weight fibroblast growth factor-2. J Biol Chem 275: 3150-3157.
    • (2000) J Biol Chem , vol.275 , pp. 3150-3157
    • Klein, S.1    Carroll, J.A.2    Chen, Y.3    Henry, M.F.4    Henry, P.A.5    Ortonowski, I.E.6
  • 19
    • 0024278417 scopus 로고
    • Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor
    • Lobb RR. (1988). Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor. Biochemistry 27: 2572-2578.
    • (1988) Biochemistry , vol.27 , pp. 2572-2578
    • Lobb, R.R.1
  • 20
    • 0742305311 scopus 로고    scopus 로고
    • Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
    • Malecki J, Wesche J, Skjerpen CS, Wiedlocha A, Olsnes S. (2004). Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism. Mol Biol Cell 15: 801-814.
    • (2004) Mol Biol Cell , vol.15 , pp. 801-814
    • Malecki, J.1    Wesche, J.2    Skjerpen, C.S.3    Wiedlocha, A.4    Olsnes, S.5
  • 21
    • 0141819118 scopus 로고    scopus 로고
    • Thrombin: Can't live without it; probably die from it
    • Mann KG. (2003). Thrombin: can't live without it; probably die from it. Chest 124: 1S-3S.
    • (2003) Chest , vol.124
    • Mann, K.G.1
  • 22
    • 0026351399 scopus 로고
    • Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner
    • Mignatti P, Morimoto T, Rifkin DB. (1991). Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc Natl Acad Sci USA 88: 11007-11011.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11007-11011
    • Mignatti, P.1    Morimoto, T.2    Rifkin, D.B.3
  • 23
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS et al. (2000). Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem 275: 13502-13509.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6
  • 24
    • 0035081241 scopus 로고    scopus 로고
    • Fibroblast growth factors
    • REVIEWS3005
    • Ornitz DM, Itoh N. (2001). Fibroblast growth factors. Genome Biol 2, REVIEWS3005.
    • (2001) Genome Biol , vol.2
    • Ornitz, D.M.1    Itoh, N.2
  • 27
    • 0029779287 scopus 로고    scopus 로고
    • Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution
    • Pintucci G, Quarto N, Rifkin DB. (1996). Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution. Mol Biol Cell 7: 1249-1258.
    • (1996) Mol Biol Cell , vol.7 , pp. 1249-1258
    • Pintucci, G.1    Quarto, N.2    Rifkin, D.B.3
  • 28
    • 0031003038 scopus 로고    scopus 로고
    • The 27-kDa heat shock protein facilitates basic fibroblast growth factor release from endothelial cells
    • Piotrowicz RS, Martin JL, Dillman WH, Levin EG. (1997). The 27-kDa heat shock protein facilitates basic fibroblast growth factor release from endothelial cells. J Biol Chem 272: 7042-7047.
    • (1997) J Biol Chem , vol.272 , pp. 7042-7047
    • Piotrowicz, R.S.1    Martin, J.L.2    Dillman, W.H.3    Levin, E.G.4
  • 29
    • 0008566513 scopus 로고
    • High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons
    • Prats H, Kaghad M, Prats AC, Klagsbrun M, Lelias JM, Liauzun P et al. (1989). High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci USA 86: 1836-1840.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1836-1840
    • Prats, H.1    Kaghad, M.2    Prats, A.C.3    Klagsbrun, M.4    Lelias, J.M.5    Liauzun, P.6
  • 30
    • 23844558626 scopus 로고    scopus 로고
    • Gene profiling of cells expressing different FGF-2 forms
    • Quarto N, Fong KD, Longaker MT. (2005). Gene profiling of cells expressing different FGF-2 forms. Gene 356: 49-68.
    • (2005) Gene , vol.356 , pp. 49-68
    • Quarto, N.1    Fong, K.D.2    Longaker, M.T.3
  • 31
    • 1242297568 scopus 로고    scopus 로고
    • Thrombin- and factor Xa-induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells
    • Rauch BH, Millette E, Kenagy RD, Daum G, Clowes AW. (2004). Thrombin- and factor Xa-induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells. Circ Res 94: 340-345.
    • (2004) Circ Res , vol.94 , pp. 340-345
    • Rauch, B.H.1    Millette, E.2    Kenagy, R.D.3    Daum, G.4    Clowes, A.W.5
  • 32
    • 20444486909 scopus 로고    scopus 로고
    • Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells
    • Rauch BH, Millette E, Kenagy RD, Daum G, Fischer JW, Clowes AW. (2005). Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. J Biol Chem 280: 17507-17511.
    • (2005) J Biol Chem , vol.280 , pp. 17507-17511
    • Rauch, B.H.1    Millette, E.2    Kenagy, R.D.3    Daum, G.4    Fischer, J.W.5    Clowes, A.W.6
  • 34
    • 33646079870 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in vein grafts: Role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2
    • Sharony R, Pintucci G, Saunders PC, Grossi EA, Baumann FG, Galloway AC et al. (2006). Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2. Am J Physiol Heart Circ Physiol 290: H1651-H1659.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Sharony, R.1    Pintucci, G.2    Saunders, P.C.3    Grossi, E.A.4    Baumann, F.G.5    Galloway, A.C.6
  • 35
    • 33646362773 scopus 로고    scopus 로고
    • Functional diversity of FGF-2 isoforms by intracellular sorting
    • Sorensen V, Nilsen T, Wiedlocha A. (2006). Functional diversity of FGF-2 isoforms by intracellular sorting. BioEssays 28: 504-514.
    • (2006) BioEssays , vol.28 , pp. 504-514
    • Sorensen, V.1    Nilsen, T.2    Wiedlocha, A.3
  • 36
    • 9144247272 scopus 로고    scopus 로고
    • Shedding of membrane vesicles mediates fibroblast growth factor-2 release from cells
    • Taverna S, Ghersi G, Ginestra A, Rigogliuso S, Pecorella S, Alaimo G et al. (2003). Shedding of membrane vesicles mediates fibroblast growth factor-2 release from cells. J Biol Chem 278: 51911-51919.
    • (2003) J Biol Chem , vol.278 , pp. 51911-51919
    • Taverna, S.1    Ghersi, G.2    Ginestra, A.3    Rigogliuso, S.4    Pecorella, S.5    Alaimo, G.6
  • 37
    • 0037781523 scopus 로고    scopus 로고
    • Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons
    • Touriol C, Bornes S, Bonnal S, Audigier S, Prats H, Prats AC et al. (2003). Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons. Biol Cell 95: 169-178.
    • (2003) Biol Cell , vol.95 , pp. 169-178
    • Touriol, C.1    Bornes, S.2    Bonnal, S.3    Audigier, S.4    Prats, H.5    Prats, A.C.6
  • 38
    • 0033588371 scopus 로고    scopus 로고
    • On the mechanism of thrombin-induced angiogenesis. Potentiation of vascular endothelial growth factor activity on endothelial cells by up-regulation of its receptors
    • Tsopanoglou NE, Maragoudakis ME. (1999). On the mechanism of thrombin-induced angiogenesis. Potentiation of vascular endothelial growth factor activity on endothelial cells by up-regulation of its receptors. J Biol Chem 274: 23969-23976.
    • (1999) J Biol Chem , vol.274 , pp. 23969-23976
    • Tsopanoglou, N.E.1    Maragoudakis, M.E.2
  • 39
    • 0028955936 scopus 로고
    • Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes
    • Vagner S, Gensac MC, Maret A, Bayard F, Amalric F, Prats H et al. (1995). Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol Cell Biol 15: 35-44.
    • (1995) Mol Cell Biol , vol.15 , pp. 35-44
    • Vagner, S.1    Gensac, M.C.2    Maret, A.3    Bayard, F.4    Amalric, F.5    Prats, H.6
  • 40
    • 33947578471 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (FGF-2): The high molecular weight forms come of age
    • Yu PJ, Ferrari G, Galloway AC, Mignatti P, Pintucci G. (2007). Basic fibroblast growth factor (FGF-2): the high molecular weight forms come of age. J Cell Biochem 100: 1100-1108.
    • (2007) J Cell Biochem , vol.100 , pp. 1100-1108
    • Yu, P.J.1    Ferrari, G.2    Galloway, A.C.3    Mignatti, P.4    Pintucci, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.